PIPA560717
SHARPIN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560717-Each-of-1 | In Stock | ₹ 50,309.28 |
PIPA560717 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,309.28
GST (18%): ₹ 9,055.67
Total Price: ₹ 59,364.95
Antigen
SHARPIN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SHARPIN
Gene Alias
0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
81858
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9H0F6
Gene Symbols
SHARPIN
Immunogen
Recombinant protein corresponding to Human SHARPIN
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KSNSPPALGP EACPVSLPSP PEASTLKGPP PEADLPRSPG NLTEREELAG SLARAIAGGD EKGAAQVAAV LAQHRVALSV QLQEACFPPG Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 57%
- Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
- LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways
- Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation
- LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex
- Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.
Compare Similar Items
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Antigen: SHARPIN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SHARPIN
Gene Alias: 0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81858
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9H0F6
Gene Symbols: SHARPIN
Immunogen: Recombinant protein corresponding to Human SHARPIN
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SHARPIN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SHARPIN
Gene Alias:
0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81858
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9H0F6
Gene Symbols:
SHARPIN
Immunogen:
Recombinant protein corresponding to Human SHARPIN
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TMEM62
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM62
Gene Alias: TMEM62; Transmembrane protein 62
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 80021
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q0P6H9
Gene Symbols: TMEM62
Immunogen: Recombinant protein corresponding to Human TMEM62
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM62
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM62
Gene Alias:
TMEM62; Transmembrane protein 62
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
80021
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q0P6H9
Gene Symbols:
TMEM62
Immunogen:
Recombinant protein corresponding to Human TMEM62
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MROH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MROH1
Gene Alias: D330001F17Rik; HEAT repeat containing 7A; HEAT repeat-containing protein 7A; HEATR7A; KIAA1833; maestro heat like repeat family member 1; maestro heat-like repeat family member 1; maestro heat-like repeat-containing protein family member 1; MROH1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 727957
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8NDA8
Gene Symbols: MROH1
Immunogen: Recombinant protein corresponding to Human MROH1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MROH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MROH1
Gene Alias:
D330001F17Rik; HEAT repeat containing 7A; HEAT repeat-containing protein 7A; HEATR7A; KIAA1833; maestro heat like repeat family member 1; maestro heat-like repeat family member 1; maestro heat-like repeat-containing protein family member 1; MROH1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
727957
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8NDA8
Gene Symbols:
MROH1
Immunogen:
Recombinant protein corresponding to Human MROH1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MYST2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Kat7
Gene Alias: EC 2.3.1.48; HBO1; HBOa; histone acetyltransferase binding to ORC1; Histone acetyltransferase KAT7; histone acetyltransferase MYST2; K (lysine) acetyltransferase 7; K(lysine) acetyltransferase 7; Kat7; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST histone acetyltransferase 2; MYST protein 2; MYST2; MYST-2; ZC2HC7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11143, 217127, 303470
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.4 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O95251, Q5SVQ0, Q810T5
Gene Symbols: Kat7
Immunogen: Recombinant protein corresponding to Human MYST2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MYST2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Kat7
Gene Alias:
EC 2.3.1.48; HBO1; HBOa; histone acetyltransferase binding to ORC1; Histone acetyltransferase KAT7; histone acetyltransferase MYST2; K (lysine) acetyltransferase 7; K(lysine) acetyltransferase 7; Kat7; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST histone acetyltransferase 2; MYST protein 2; MYST2; MYST-2; ZC2HC7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11143, 217127, 303470
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.4 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O95251, Q5SVQ0, Q810T5
Gene Symbols:
Kat7
Immunogen:
Recombinant protein corresponding to Human MYST2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG