PIPA561019

SKA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA561019-Each-of-1 In Stock ₹ 50,309.28

PIPA561019 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

SKA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SKA1

Gene Alias

2810433K01Rik; AV117428; C18orf24; RGD1310784; SKA1; spindle and kinetochore associated complex subunit 1; spindle and kinetochore-associated protein 1; spindle and KT (kinetochore) associated 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

220134

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96BD8

Gene Symbols

SKA1

Immunogen

Recombinant protein corresponding to Human SKA1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: ELLNKLELEI QYQEQTNNSL KELCESLEED YKDIEHLKEN IPSHLPQVTV TQSCVKGSDL DPEEPIKVEE PEPVKKPPKE QRSIKEM Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 76%
  • Upon entry into mitosis, the cell's microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes
  • Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs
  • A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset
  • Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure
  • Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing.

Compare Similar Items

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Img

Thermo Scientific

PIPA561019

--


Antigen:
SKA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKA1

Gene Alias:
2810433K01Rik; AV117428; C18orf24; RGD1310784; SKA1; spindle and kinetochore associated complex subunit 1; spindle and kinetochore-associated protein 1; spindle and KT (kinetochore) associated 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
220134

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96BD8

Gene Symbols:
SKA1

Immunogen:
Recombinant protein corresponding to Human SKA1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA561020

--


Antigen:
SLC24A3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC24A3

Gene Alias:
Na(+)/K(+)/Ca(2+)-exchange protein 3; NCKX3; Slc24a3; sodium calcium exchanger; sodium/potassium/calcium exchanger 3; solute carrier family 24 (sodium/potassium/calcium exchanger), member 3; solute carrier family 24 member 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57419

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9HC58

Gene Symbols:
SLC24A3

Immunogen:
Recombinant protein corresponding to Human SLC24A3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA561021

--


Antigen:
KCTD18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCTD18

Gene Alias:
4932411A20Rik; 6530404F10Rik; BTB/POZ domain-containing protein KCTD18; KCTD18; potassium channel tetramerisation domain containing 18; potassium channel tetramerization domain containing 18; RGD1564820; similar to potassium channel tetramerisation domain containing 18

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
130535

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6PI47

Gene Symbols:
KCTD18

Immunogen:
Recombinant protein corresponding to Human KCTD18

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA561023

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Antigen:
EFHA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MICU2

Gene Alias:
09C01; 1110008L20Rik; 4833427E09Rik; AU041871; Calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF hand domain family, member A1; EFHA1; EF-hand domain family member A1; EF-hand domain family, member A1; EF-hand domain-containing family member A1; Micu2; mitochondrial calcium uptake 2; RGD1309934; Smhs2; Smhs2 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
221154

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8IYU8

Gene Symbols:
MICU2

Immunogen:
Recombinant protein corresponding to Human EFHA1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG