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PIPA561672

SIK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA561672-Each-of-1 In Stock ₹ 47,528.58

PIPA561672 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

SIK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SIK3

Gene Alias

5730525O22Rik; 9030204A07Rik; AI447252; AI846254; AI849445; Kiaa0999; L19; mKIAA0999; QSK; Salt-inducible kinase 3; serine/threonine-protein kinase QSK; Serine/threonine-protein kinase SIK3; SIK family kinase 3; SIK3; SIK-3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23387

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9Y2K2

Gene Symbols

SIK3

Immunogen

Recombinant protein corresponding to Human SIK3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: QQEYQELFRH MNQGDAGSLA PSLGGQSMTE RQALSYQNAD SYHHHTSPQH LLQIRAQECV SQASSPTPPH GYAHQPALMH SESMEEDCSC EGAKDGFQD Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 80%
  • SIK3 (QSK) is a serine/threonine-protein kinase, belongs to QIK subfamily
  • The phosphorylation of SIK3 by LKB1 through the 14-3-3 binding enhances its catalytic activity and leads its localization to punctate structures within the cytoplasm
  • Overexpression of SIK3 promotes G1/S cell cycle progression with ovarian cancer
  • There are two sites (H331L and A1103V) were mutated at significant frequency in breast cancer
  • SIK3 is a novel tumor-associated antigen (TAA)
  • SIK3 is a positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor
  • Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis
  • Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3.

Compare Similar Items

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Img

Thermo Scientific

PIPA561672

--

Antigen:
SIK3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SIK3
Gene Alias:
5730525O22Rik; 9030204A07Rik; AI447252; AI846254; AI849445; Kiaa0999; L19; mKIAA0999; QSK; Salt-inducible kinase 3; serine/threonine-protein kinase QSK; Serine/threonine-protein kinase SIK3; SIK family kinase 3; SIK3; SIK-3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23387
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9Y2K2
Gene Symbols:
SIK3
Immunogen:
Recombinant protein corresponding to Human SIK3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA561673

--

Antigen:
APOA1BP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NAXE
Gene Alias:
AA087124; AIBP; AI-BP; AI-BP {ECO:0000255; Apoa1bp; Apoa1ip; apoA-I binding protein; apolipoprotein A-I binding protein; apolipoprotein A-I interacting protein; apolipoprotein A-I-binding protein; apolipoprotein A-I-binding protein {ECO:0000255; ESTM37; HAMAP-Rule:MF_03159}; MGC119143; MGC119144; MGC119145; NAD(P)H-hydrate epimerase; NAD(P)H-hydrate epimerase {ECO:0000255; NAD(P)HX epimerase; NAD(P)HX epimerase {ECO:0000255; NAXE; YjeF N-terminal domain-containing protein 1; yjeF_N1; YJEFN1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
128240
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8NCW5
Gene Symbols:
NAXE
Immunogen:
Recombinant protein corresponding to Human APOA1BP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA561674

--

Antigen:
CCDC140
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCDC140
Gene Alias:
CCDC140; coiled-coil domain containing 140; coiled-coil domain-containing protein 140
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
151278
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q96MF4
Gene Symbols:
CCDC140
Immunogen:
Recombinant protein corresponding to Human CCDC140
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA561676

--

Antigen:
TBC1D2B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBC1D2B
Gene Alias:
KIAA1055; TBC1 domain family member 2B; TBC1 domain family, member 2B; TBC1D2B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23102
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9UPU7
Gene Symbols:
TBC1D2B
Immunogen:
Recombinant protein corresponding to Human TBC1D2B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG