PIPA562197

FPGS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA562197-Each-of-1 In Stock ₹ 47,015.22

PIPA562197 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

FPGS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FPGS

Gene Alias

AA408187; folylpoly-gamma-glutamate synthetase; folylpolyglutamate synthase; folylpolyglutamate synthase, mitochondrial; folylpolyglutamyl synthetase; FPGS; Tetrahydrofolate synthase; tetrahydrofolylpolyglutamate synthase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2356

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.5 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q05932

Gene Symbols

FPGS

Immunogen

Recombinant protein corresponding to Human FPGS

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RVLLFNATGD RDPAALLKLL QPCQFDYAVF CPNLTEVSST GNADQQNFTV TLDQVLLRCL EHQQHWNHLD EEQASPDLWS APSPEPGGSA SLLL Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 74%
  • Folylpoly-gamma-glutamate synthetase (FPGS) catalyzes the addition of several equivalents of glutamic acid to the gamma-carboxyl group in the side chain of folate cofactors and analogs
  • Folylpoly-gamma-glutamate synthetase has three functions in folate homeostasis in mammals: polyglutamation prevents efflux of folate cofactors from the cell, it increases the binding of folate cofactors to some of the enzymes of folate interconversion and biosynthesis, and it appears to allow the accumulation of folates in the mitochondria that are required for glycine synthesis
  • Folylpoly-gamma-glutamate synthetase is widely expressed in human tumors and is tightly linked either to proliferation or to a lack of differentiation
  • The cytotoxicity of both thymidylate synthase and purine inhibitors requires continued inhibition of target for greater than one generation time, so that the integrative function of FPGS adds considerably to the efficiency of folate antimetabolites.

Compare Similar Items

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Thermo Scientific

PIPA562197

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Antigen:
FPGS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FPGS

Gene Alias:
AA408187; folylpoly-gamma-glutamate synthetase; folylpolyglutamate synthase; folylpolyglutamate synthase, mitochondrial; folylpolyglutamyl synthetase; FPGS; Tetrahydrofolate synthase; tetrahydrofolylpolyglutamate synthase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2356

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q05932

Gene Symbols:
FPGS

Immunogen:
Recombinant protein corresponding to Human FPGS

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562200

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Antigen:
EPX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPX

Gene Alias:
eosinophil peroxidase; Eosinophil peroxidase heavy chain; Eosinophil peroxidase light chain; EPER; EPO; EPP; Epx; EPX PEN; EPXD; EPX-PEN; PERE

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8288

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.08 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P11678

Gene Symbols:
EPX

Immunogen:
Recombinant protein corresponding to Human EPX

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562201

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Antigen:
DPP6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DPP6

Gene Alias:
B930011P16Rik; D5Buc3; D5Buc4; D5Buc5; dipeptidyl aminopeptidase IV-related protein; dipeptidyl aminopeptidase-like protein 6; Dipeptidyl aminopeptidase-related protein; Dipeptidyl peptidase 6; Dipeptidyl peptidase IV-like protein; dipeptidyl peptidase IV-related protein; dipeptidyl peptidase like 6; dipeptidyl peptidase VI; dipeptidylpeptidase 6; dipeptidyl-peptidase 6; dipeptidylpeptidase VI; DPL1; DPP VI; Dpp6; Dpp-6; DPPX; Gm1377; In(5)6H p; In(5)6H-p; inversion, Chr 5, Harwell 6, proximal; MRD33; Peplb; Rw; VF2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13483, 1804

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.10 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P42658, Q9Z218

Gene Symbols:
DPP6

Immunogen:
Recombinant protein corresponding to Human DPP6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562204

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Antigen:
HSD3B7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HSD3B7

Gene Alias:
3 beta-hydroxy-delta 5-C27-steroid oxidoreductase; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; AI195443; BB098564; C(27) 3-beta-HSD; C(27)-3BETA-HSD; CBAS1; Cca2; cholest-5-ene-3-be; cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; Confluent 3Y1 cell-associated 2; HSD3B7; hsd3b7 {ECO:0000312; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; PFIC4; RGD:628727}; SDR11E3; short chain dehydrogenase/reductase family 11E, member 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80270

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H2F3

Gene Symbols:
HSD3B7

Immunogen:
Recombinant protein corresponding to Human HSD3B7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG