PIPA562266

C10orf99 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA562266-Each-of-1 In Stock ₹ 50,651.52

PIPA562266 - Each of 1

₹ 50,651.52

In Stock

Quantity

1

Base Price: ₹ 50,651.52

GST (18%): ₹ 9,117.274

Total Price: ₹ 59,768.794

Antigen

C10orf99

Classification

Polyclonal

Conjugate

Unconjugated

Gene

C10orf99

Gene Alias

Antimicrobial peptide with 57 amino acid residues; anti-microbial peptide with 57 amino acid residues; antimicrobial peptide-57; AP-57; C10orf99; chromosome 10 open reading frame 99; colon-derived SUSD2 binding factor; CSBF; GPR15L; Protein GPR15L; RLLV1833; secreted protein C10orf99; UNQ1833; UNQ1833/PRO3446

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

387695

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.15 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6UWK7

Gene Symbols

C10orf99

Immunogen

Recombinant protein corresponding to Human C10orf99

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: KRRPAKAWSG RRTRLCCHRV PSPNSTNLKG HHVRLCKPCK LEPEPRLWVV PGALPQV Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 46%
  • GPR15L is a newly identified ligand for GPR15, a member of the G protein-coupled receptor (GPCR) family
  • Upon ligation, GPR15L acts as a potent chemoattractant for GPR15-expressing T cells and together they mediate lymphocyte recruitment to the large intestine and skin
  • GPR15L is constitutively expressed by colon epithelial cells where its expression is minimally altered by intestinal inflammation
  • Conversely, GPR15L is nearly undetectable in adult epidermis but highly upregulated during wound healing and inflammation, particularly in psoriasis
  • Significant expression of GPR15L is also seen in additional mucosal epithelial cells, including those of the stomach, esophagus, and urinary tract
  • While maintaining similar expression patterns and intramolecular disulfide cysteine bridges found in members of the CC chemokine family, GPR15L differs from classic CC and CXC chemokines, whose active sites are found on the N-terminus, in that it relies on its C-terminus for receptor interaction
  • GPR15L was first identified as an antimicrobial peptide (AMP) due to its broad spectrum of antimicrobial activity, a property shared with many chemokines
  • GPR15L binds to an additional receptor, SUSD2, and early studies have indicated that both are downregulated in colon cancer tissue resulting in inhibited colon cancer growth.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA562266

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Antigen:
C10orf99

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C10orf99

Gene Alias:
Antimicrobial peptide with 57 amino acid residues; anti-microbial peptide with 57 amino acid residues; antimicrobial peptide-57; AP-57; C10orf99; chromosome 10 open reading frame 99; colon-derived SUSD2 binding factor; CSBF; GPR15L; Protein GPR15L; RLLV1833; secreted protein C10orf99; UNQ1833; UNQ1833/PRO3446

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
387695

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.15 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6UWK7

Gene Symbols:
C10orf99

Immunogen:
Recombinant protein corresponding to Human C10orf99

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562267

--


Antigen:
C14orf140

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZC2HC1C

Gene Alias:
2810002I04Rik; AV046379; C14orf140; FAM164C; family with sequence similarity 164, member C; protein FAM164C; RGD1307122; ZC2HC1C; Zinc finger C2HC domain-containing protein 1C; zinc finger C2HC-type containing 1C; zinc finger, C2HC-type containing 1C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79696

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q53FD0

Gene Symbols:
ZC2HC1C

Immunogen:
Recombinant protein corresponding to Human C14orf140

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562269

--


Antigen:
CYSTM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYSTM1

Gene Alias:
C5orf32; cysteine rich transmembrane module containing 1; cysteine-rich and transmembrane domain-containing protein 1; cysteine-rich transmembrane module containing 1; CYSTM1; ORF1-FL49; putative nuclear protein ORF1-FL49; UPF0467 protein C5orf32

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84418

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H1C7

Gene Symbols:
CYSTM1

Immunogen:
Recombinant protein corresponding to Human CYSTM1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562270

--


Antigen:
RNF170

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNF170

Gene Alias:
6720407G21Rik; ADSA; AI481227; E3 ubiquitin-protein ligase RNF170; putative LAG1-interacting protein; RING finger protein 170; RING finger protein 170; E3 ubiquitin-protein ligase RNF170; RING-type E3 ubiquitin transferase RNF170; Rnf170; SNAX1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
81790

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96K19

Gene Symbols:
RNF170

Immunogen:
Recombinant protein corresponding to Human RNF170

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG