PIPA562438

MEPCE Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA562438-Each-of-1 In Stock ₹ 47,015.22

PIPA562438 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

MEPCE

Classification

Polyclonal

Conjugate

Unconjugated

Gene

mepce

Gene Alias

7SK snRNA methylphosphate capping enzyme; BCDIN3; Bicoid-interacting protein 3 homolog; bin3 homolog; bin3, bicoid-interacting 3; bin3, bicoid-interacting 3, homolog; Bipl1; D5Wsu46e; fc59f06; FLJ20257; Mepce; methylphosphate capping enzyme; si:ch211-283h6.1; wu:fc59f06; zBCDIN3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56257

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q7L2J0

Gene Symbols

mepce

Immunogen

Recombinant protein corresponding to Human MEPCE

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: AQTPEYDVVL CLSLTKWVHL NWGDEGLKRM FRRIYRHLRP GGILVLEPQP WSSYGKRKTL TETIYKNYYR IQLKPEQFSS YLTSPDVGFS SYELVATPHN TSKGFQRPVY Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%
  • S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA (7SK RNA), leading to stabilize it (PubMed:17643375, PubMed:19906723, PubMed:30559425)
  • Also has a non-enzymatic function as part of the 7SK RNP complex: the 7SK RNP complex sequesters the positive transcription elongation factor b (P-TEFb) in a large inactive 7SK RNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:17643375)
  • The 7SK RNP complex also promotes snRNA gene transcription by RNA polymerase II via interaction with the little elongation complex (LEC) (PubMed:28254838)
  • In the 7SK RNP complex, MEPCE is required to stabilize 7SK RNA and facilitate the assembly of 7SK RNP complex (PubMed:19906723)
  • MEPCE has a non-enzymatic function in the 7SK RNP complex; interaction with LARP7 within the 7SK RNP complex occluding its catalytic center (PubMed:19906723)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA562438

--


Antigen:
MEPCE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
mepce

Gene Alias:
7SK snRNA methylphosphate capping enzyme; BCDIN3; Bicoid-interacting protein 3 homolog; bin3 homolog; bin3, bicoid-interacting 3; bin3, bicoid-interacting 3, homolog; Bipl1; D5Wsu46e; fc59f06; FLJ20257; Mepce; methylphosphate capping enzyme; si:ch211-283h6.1; wu:fc59f06; zBCDIN3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56257

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q7L2J0

Gene Symbols:
mepce

Immunogen:
Recombinant protein corresponding to Human MEPCE

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562439

--


Antigen:
FRAS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FRAS1

Gene Alias:
bl; blebbed; E130113P14Rik; extracellular matrix protein FRAS1; FLJ14927; FLJ22031; FRAS1; Fraser extracellular matrix complex subunit 1; Fraser syndrome 1; Fraser syndrome 1 homolog (human); Fraser syndrome 1 protein; Kiaa1500; mKIAA1500

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80144

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q86XX4

Gene Symbols:
FRAS1

Immunogen:
Recombinant protein corresponding to Human FRAS1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562440

--


Antigen:
PPP1R35

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPP1R35

Gene Alias:
2010007H12Rik; 2010011D20Rik; AL024004; C7orf47; PPP1R35; Protein phosphatase 1 regulatory subunit 35; protein phosphatase 1, regulatory subunit 35; UPF0683 protein C7orf47; UPF0683 protein C7orf47 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
221908

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8TAP8

Gene Symbols:
PPP1R35

Immunogen:
Recombinant protein corresponding to Human PPP1R35

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA562441

--


Antigen:
GTF3C1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTF3C1

Gene Alias:
DKFZp686A111; general transcription factor 3C polypeptide 1; general transcription factor IIIC subunit 1; general transcription factor IIIC, polypeptide 1 (alpha subunit); general transcription factor IIIC, polypeptide 1, alpha 220kDa; GTF3C1; TF3C-alpha; TFIIIC; TFIIIC 220 kDa subunit; TFIIIC box B-binding subunit; TFIIIC220; TFIIICalpha; transcription factor IIIC 220 kDa subunit; Transcription factor IIIC subunit alpha

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2975

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q12789

Gene Symbols:
GTF3C1

Immunogen:
Recombinant protein corresponding to Human GTF3C1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG