PIPA563025
LARP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA563025-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA563025 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
LARP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Larp1
Gene Alias
0031/08; 0225/29; 1810024J12Rik; 3110040D16Rik; BcDNA:LD02611; CG14065; CG14066; CG42551; CG42551-PA; CG42551-PB; CG42551-PD; CG42551-PE; CG42551-PF; CG42551-PG; CG42551-PH; dlarp; Dmel\CG42551; Dmel_CG42551; drosophila La related protein; KIAA0731; l(3)S003108; l(3)S022529; La related protein; La ribonucleoprotein domain family member 1; La ribonucleoprotein domain family, member 1; La-related protein; la-related protein 1; Larp; Larp1; larp-PA; larp-PB; larp-PD; larp-PE; larp-PF; larp-PG; larp-PH; lethal (3) S003108; lethal (3) S022529; meteor; mKIAA0731; RGD1306683
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23367
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q6PKG0
Gene Symbols
Larp1
Immunogen
Recombinant protein corresponding to Human LARP1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: PLQIDMKPEV PREKLASRPT RPPEPRHIPA NRGEIKGSES ATYVPVAPPT PAWQPEIKPE PAWHDQDETS SVKSDG Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 82%
- RNA-binding protein that regulates the translation of specific target mRNA species downstream of the mTORC1 complex, in function of growth signals and nutrient availability (PubMed:20430826, PubMed:23711370, PubMed:24532714, PubMed:25940091, PubMed:28650797, PubMed:28673543, PubMed:29244122)
- Interacts on the one hand with the 3' poly-A tails that are present in all mRNA molecules, and on the other hand with the 7-methylguanosine cap structure of mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding ribosomal proteins and several components of the translation machinery (PubMed:23711370, PubMed:25940091, PubMed:28650797, PubMed:29244122, PubMed:26206669, PubMed:28379136)
- The interaction with the 5' end of mRNAs containing a 5'TOP motif leads to translational repression by preventing the binding of EIF4G1 (PubMed:25940091, PubMed:28650797, PubMed:29244122, PubMed:28379136)
- When mTORC1 is activated, LARP1 is phosphorylated and dissociates from the 5' untranslated region (UTR) of mRNA (PubMed:25940091, PubMed:28650797)
- Does not prevent binding of EIF4G1 to mRNAs that lack a 5'TOP motif (PubMed:28379136)
- Interacts with the free 40S ribosome subunit and with ribosomes, both monosomes and polysomes (PubMed:20430826, PubMed:24532714, PubMed:25940091, PubMed:28673543)
- Under normal nutrient availability, interacts primarily with the 3' untranslated region (UTR) of mRNAs encoding ribosomal proteins and increases protein synthesis (PubMed:23711370, PubMed:28650797)
- Associates with actively translating ribosomes and stimulates translation of mRNAs containing a 5'TOP motif, thereby regulating protein synthesis, and as a consequence, cell growth and proliferation (PubMed:20430826, PubMed:24532714)
- Stabilizes mRNAs species with a 5'TOP motif, which is required to prevent apoptosis (PubMed:20430826, PubMed:23711370, PubMed:25940091, PubMed:28673543)
- [UniProt]
Compare Similar Items
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Antigen: LARP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Larp1
Gene Alias: 0031/08; 0225/29; 1810024J12Rik; 3110040D16Rik; BcDNA:LD02611; CG14065; CG14066; CG42551; CG42551-PA; CG42551-PB; CG42551-PD; CG42551-PE; CG42551-PF; CG42551-PG; CG42551-PH; dlarp; Dmel\CG42551; Dmel_CG42551; drosophila La related protein; KIAA0731; l(3)S003108; l(3)S022529; La related protein; La ribonucleoprotein domain family member 1; La ribonucleoprotein domain family, member 1; La-related protein; la-related protein 1; Larp; Larp1; larp-PA; larp-PB; larp-PD; larp-PE; larp-PF; larp-PG; larp-PH; lethal (3) S003108; lethal (3) S022529; meteor; mKIAA0731; RGD1306683
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23367
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q6PKG0
Gene Symbols: Larp1
Immunogen: Recombinant protein corresponding to Human LARP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
LARP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Larp1
Gene Alias:
0031/08; 0225/29; 1810024J12Rik; 3110040D16Rik; BcDNA:LD02611; CG14065; CG14066; CG42551; CG42551-PA; CG42551-PB; CG42551-PD; CG42551-PE; CG42551-PF; CG42551-PG; CG42551-PH; dlarp; Dmel\CG42551; Dmel_CG42551; drosophila La related protein; KIAA0731; l(3)S003108; l(3)S022529; La related protein; La ribonucleoprotein domain family member 1; La ribonucleoprotein domain family, member 1; La-related protein; la-related protein 1; Larp; Larp1; larp-PA; larp-PB; larp-PD; larp-PE; larp-PF; larp-PG; larp-PH; lethal (3) S003108; lethal (3) S022529; meteor; mKIAA0731; RGD1306683
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23367
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q6PKG0
Gene Symbols:
Larp1
Immunogen:
Recombinant protein corresponding to Human LARP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PTPRK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPRK
Gene Alias: AI853699; dJ480J14.2.1 (protein tyrosine phosphatase, receptor type, K (R-PTP-KAPPA, protein tyrosine phosphatase kappa , protein tyrosine phosphatase kappa; protein tyrosine phosphatase, receptor type K; protein tyrosine phosphatase, receptor type, K; protein tyrosine phosphatase, receptor type, K, extracellular region; protein-tyrosine phosphatase kappa; protein-tyrosine phosphatase, receptor type, kappa; Ptpk; PTPRK; receptor-like protein tyrosine phosphatase kappa extracellular region (RPTPK); receptor-type tyrosine-protein phosphatase kappa; Rptpk; R-PTPk; R-PTP-k; RPTPkappa; R-PTP-kappa
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5796
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q15262
Gene Symbols: PTPRK
Immunogen: Recombinant protein corresponding to Human PTPRK
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PTPRK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPRK
Gene Alias:
AI853699; dJ480J14.2.1 (protein tyrosine phosphatase, receptor type, K (R-PTP-KAPPA, protein tyrosine phosphatase kappa , protein tyrosine phosphatase kappa; protein tyrosine phosphatase, receptor type K; protein tyrosine phosphatase, receptor type, K; protein tyrosine phosphatase, receptor type, K, extracellular region; protein-tyrosine phosphatase kappa; protein-tyrosine phosphatase, receptor type, kappa; Ptpk; PTPRK; receptor-like protein tyrosine phosphatase kappa extracellular region (RPTPK); receptor-type tyrosine-protein phosphatase kappa; Rptpk; R-PTPk; R-PTP-k; RPTPkappa; R-PTP-kappa
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5796
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q15262
Gene Symbols:
PTPRK
Immunogen:
Recombinant protein corresponding to Human PTPRK
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ABCA9
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABCA9
Gene Alias: ABCA9; ATP binding cassette subfamily A member 9; ATP-binding cassette A9; ATP-binding cassette sub-family A member 9; ATP-binding cassette transporter sub-family A member 9; ATP-binding cassette, subfamily A (ABC1), member 9; ATP-binding cassette, sub-family A (ABC1), member 9; D630040K07Rik; DKFZp686F2450; EST640918; MGC75415
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10350
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.4 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8IUA7
Gene Symbols: ABCA9
Immunogen: Recombinant protein corresponding to Human ABCA9
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ABCA9
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABCA9
Gene Alias:
ABCA9; ATP binding cassette subfamily A member 9; ATP-binding cassette A9; ATP-binding cassette sub-family A member 9; ATP-binding cassette transporter sub-family A member 9; ATP-binding cassette, subfamily A (ABC1), member 9; ATP-binding cassette, sub-family A (ABC1), member 9; D630040K07Rik; DKFZp686F2450; EST640918; MGC75415
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10350
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.4 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8IUA7
Gene Symbols:
ABCA9
Immunogen:
Recombinant protein corresponding to Human ABCA9
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TIGD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TIGD2
Gene Alias: 3632410O17Rik; epididymis luminal protein 106; HEL106; LOC100912924; Tigd2; tigger transposable element derived 2; tigger transposable element derived 2 homolog; tigger transposable element-derived protein 2; uncharacterized LOC100912924
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 166815
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q4W5G0
Gene Symbols: TIGD2
Immunogen: Recombinant protein corresponding to Human TIGD2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TIGD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TIGD2
Gene Alias:
3632410O17Rik; epididymis luminal protein 106; HEL106; LOC100912924; Tigd2; tigger transposable element derived 2; tigger transposable element derived 2 homolog; tigger transposable element-derived protein 2; uncharacterized LOC100912924
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
166815
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q4W5G0
Gene Symbols:
TIGD2
Immunogen:
Recombinant protein corresponding to Human TIGD2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG