PIPA563689

SKA2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA563689-Each-of-1 In Stock ₹ 47,015.22

PIPA563689 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SKA2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SKA2

Gene Alias

1110001A07Rik; C78640; FAM33A; family with sequence similarity 33, member A; Protein FAM33A; RGD1307084; Ska2; spindle and kinetochore associated complex subunit 2; spindle and kinetochore-associated protein 2; spindle and KT (kinetochore) associated 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

348235

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8WVK7

Gene Symbols

SKA2

Immunogen

Recombinant protein corresponding to Human SKA2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: EAEVDKLELM FQKAESDLDY IQYRLEYEIK TNHPDSASEK NPVTLLKELS VIKS Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 81%
  • Upon entry into mitosis, the cell’s microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes
  • Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs
  • A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset
  • Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure
  • Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing
  • SKA2 has also been shown to interact with glucocorticoid receptors and to be involved in glucocorticoid signaling and cell proliferation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA563689

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Antigen:
SKA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKA2

Gene Alias:
1110001A07Rik; C78640; FAM33A; family with sequence similarity 33, member A; Protein FAM33A; RGD1307084; Ska2; spindle and kinetochore associated complex subunit 2; spindle and kinetochore-associated protein 2; spindle and KT (kinetochore) associated 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
348235

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8WVK7

Gene Symbols:
SKA2

Immunogen:
Recombinant protein corresponding to Human SKA2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563690

--


Antigen:
PSD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSD

Gene Alias:
1110007H17Rik; A930015K15; EFA6; EFA6A; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6; Exchange factor for ARF6; Exchange factor for ARF6 A; KIAA2011; mKIAA2011; PH and SEC7 domain-containing protein 1; pleckstrin and Sec7 domain containing; pleckstrin and Sec7 domain containing homolog; pleckstrin homology and SEC7 domain-containing protein 1; pleckstrin-Sec7 domains-containing; Psd; Psd1; Psdl; TYL

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5662

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
A5PKW4

Gene Symbols:
PSD

Immunogen:
Recombinant protein corresponding to Human PSD

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA563693

--


Antigen:
NDUFA7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ndufa7

Gene Alias:
14.5kDa; 2400007M02Rik; B14.5a; CI-B14.5a; complex I B14.5a subunit; complex I-B14.5a; NADH dehydrogenase; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7; NADH:ubiquinone oxidoreductase subunit A7; NADH-ubiquinone oxidoreductase subunit B14.5a; Ndufa7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4701

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O95182

Gene Symbols:
Ndufa7

Immunogen:
Recombinant protein corresponding to Human NDUFA7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563696

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Antigen:
ABHD16B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABHD16B

Gene Alias:
ABHD16B; abhydrolase domain containing 16B; abhydrolase domain-containing protein 16B; Alpha/beta hydrolase domain-containing protein 16B; C20orf135; dJ591C20.1; protein ABHD16B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140701

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H3Z7

Gene Symbols:
ABHD16B

Immunogen:
Recombinant protein corresponding to Human ABHD16B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG