PIPA563855

NUDT16 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA563855-Each-of-1 In Stock ₹ 47,015.22

PIPA563855 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

NUDT16

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NUDT16

Gene Alias

2310041H06Rik; 2810047L04Rik; 2900006H04Rik; AI851783; IDP phosphatase; IDPase; inosine diphosphate phosphatase; LOC100718706; m7GpppN-mRNA hydrolase; nucleoside diphosphate-linked moiety X motif 16; nudix; nudix (nucleoside diphosphate linked moiety X)-type motif 16; nudix hydrolase 16; Nudix motif 16; nudix-type motif 16; NUDT16; RGD1311387; testicular tissue protein Li 129; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

131870

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96DE0

Gene Symbols

NUDT16

Immunogen

Recombinant protein corresponding to Human NUDT16

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA563613

--

Img

Thermo Scientific

PIPA563579

--

Img

Thermo Scientific

PIPA563087

--

Img

Thermo Scientific

PIPA562822

--

Img

Thermo Scientific

PIPA563127

--

Img

Thermo Scientific

PIPA562425

--

Img

Thermo Scientific

PIPA563340

--

Img

Thermo Scientific

PIPA563616

--

Description

  • Immunogen sequence: VERPDYRSSH AGSRPRVVAH FYAKSL Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 73%
  • RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner
  • Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA
  • Has diphosphatase activity and removes m7G and/or m227G caps from U8 snoRNA and leaves a 5'monophosphate on the RNA
  • Catalyzes also the cleavage of the cap structure on mRNAs
  • Does not hydrolyze cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG)
  • Also hydrolysis m7G- and m227G U3-capped RNAs but with less efficiencies
  • Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species
  • Binds to the U8 snoRNA; metal is not required for RNA-binding
  • May play a role in the regulation of snoRNAs and mRNAs degradation
  • Acts also as a phosphatase; hydrolyzes the non-canonical purine nucleotides inosine diphosphate (IDP) and deoxyinosine diphosphate (dITP) as well as guanosine diphosphate (GDP), deoxyguanosine diphosphate (dGDP), xanthine diphosphate (XDP), inosine triphosphate (ITP) and deoxyinosine triphosphate (ITP) to their respective monophosphate derivatives and does not distinguish between the deoxy- and ribose forms (PubMed:20385596, PubMed:26121039)
  • The order of activity with different substrates is IDP > dIDP >> GDP = dGDP > XDP = ITP = dITP (PubMed:20385596)
  • Binds strongly to GTP, ITP and XTP
  • Participates in the hydrolysis of dIDP/IDP and probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions (PubMed:20385596)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA563855

--


Antigen:
NUDT16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUDT16

Gene Alias:
2310041H06Rik; 2810047L04Rik; 2900006H04Rik; AI851783; IDP phosphatase; IDPase; inosine diphosphate phosphatase; LOC100718706; m7GpppN-mRNA hydrolase; nucleoside diphosphate-linked moiety X motif 16; nudix; nudix (nucleoside diphosphate linked moiety X)-type motif 16; nudix hydrolase 16; Nudix motif 16; nudix-type motif 16; NUDT16; RGD1311387; testicular tissue protein Li 129; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
131870

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96DE0

Gene Symbols:
NUDT16

Immunogen:
Recombinant protein corresponding to Human NUDT16

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563856

--


Antigen:
VSIG10L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VSIG10L

Gene Alias:
V-set and immunoglobulin domain containing 10 like; V-set and immunoglobulin domain-containing protein 10-like; VSIG10L; VSIG10-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
147645

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q86VR7

Gene Symbols:
VSIG10L

Immunogen:
Recombinant protein corresponding to Human VSIG10L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563857

--


Antigen:
FKRP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FKRP

Gene Alias:
A830029B19Rik; AI842067; AI847300; FKRP; fukutin related protein; fukutin-related protein; LGMD1I; LGMD2I; MDC1C; MDDGA5; MDDGB5; MDDGC5; Ribitol-5-phosphate transferase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79147

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H9S5

Gene Symbols:
FKRP

Immunogen:
Recombinant protein corresponding to Human FKRP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563859

--


Antigen:
NALP13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NLRP13

Gene Alias:
CLR19.7; NACHT, leucine rich repeat and PYD containing 13; NACHT, LRR and PYD containing protein 13; NACHT, LRR and PYD domains-containing protein 13; NALP13; NLR family pyrin domain containing 13; NLR family, pyrin domain containing 13; NLRP13; NOD14; Nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13; PAN13

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126204

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q86W25

Gene Symbols:
NLRP13

Immunogen:
Recombinant protein corresponding to Human NALP13

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG