PIPA563928

ASAH2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA563928-Each-of-1 In Stock ₹ 47,100.78

PIPA563928 - Each of 1

₹ 47,100.78

In Stock

Quantity

1

Base Price: ₹ 47,100.78

GST (18%): ₹ 8,478.14

Total Price: ₹ 55,578.92

Antigen

ASAH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Asah2

Gene Alias

acylsphingosine deacylase 2; AI585898; Asah2; BCDase; hCD; HNAC1; LCDase; mitochondrial ceramidase; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; N-acylsphingosine amidohydrolase 2; NCDase; N-CDase; Neutral ceramidase; Neutral ceramidase soluble form; neutral/alkaline ceramidase; non-lysosomal ceramidase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56624

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NR71

Gene Symbols

Asah2

Immunogen

Recombinant protein corresponding to Human ASAH2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RTFGDVLQPA KPEYRVGEVA EVIFVGANPK NSVQNQNHQT Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%
  • Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids
  • These ceramidases are classified according to the pH range that supports their optimal activity
  • ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5
  • ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine
  • Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger
  • ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart
  • Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA563928

--


Antigen:
ASAH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Asah2

Gene Alias:
acylsphingosine deacylase 2; AI585898; Asah2; BCDase; hCD; HNAC1; LCDase; mitochondrial ceramidase; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; N-acylsphingosine amidohydrolase 2; NCDase; N-CDase; Neutral ceramidase; Neutral ceramidase soluble form; neutral/alkaline ceramidase; non-lysosomal ceramidase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56624

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NR71

Gene Symbols:
Asah2

Immunogen:
Recombinant protein corresponding to Human ASAH2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563929

--


Antigen:
EGFL8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EGFL8

Gene Alias:
C6orf8; EGF like domain multiple 8; EGFL8; EGF-like domain 8; EGF-like domain-containing protein 8; EGF-like protein 8; EGF-like-domain protein 8; EGF-like-domain, multiple 8; Epidermal growth factor-like protein 8; multiple EGF-like domain protein 8; NG3; NG3 protein; UNQ8752/PRO29920; Vascular endothelial statin-2; VE-statin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80864

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q99944

Gene Symbols:
EGFL8

Immunogen:
Recombinant protein corresponding to Human EGFL8

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563930

--


Antigen:
C4orf33

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C4orf33

Gene Alias:
C4orf33; chromosome 4 open reading frame 33; UPF0462 protein C4orf33

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
132321

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8N1A6

Gene Symbols:
C4orf33

Immunogen:
Recombinant protein corresponding to Human C4orf33

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563932

--


Antigen:
ZNF736

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF736

Gene Alias:
KRAB-containing zinc-finger repressor protein; zinc finger protein 736; ZNF736

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
728927

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.7 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
B4DX44

Gene Symbols:
ZNF736

Immunogen:
Recombinant protein corresponding to Human ZNF736

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG