PIPA563970

GRF-1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA563970-Each-of-1 In Stock ₹ 47,015.22

PIPA563970 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

GRF-1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARHGAP35

Gene Alias

6430596G11Rik; AI841135; ARHGAP35; GAP-associated protein p190; glucocorticoid receptor DNA binding factor 1; Glucocorticoid receptor DNA-binding factor 1; Glucocorticoid receptor repression factor 1; GRF1; GRF-1; GRLF1; KIAA1722; LOW QUALITY PROTEIN: rho GTPase-activating protein 35; MGC10745; mKIAA1722; P190 RhoGAP; P190A; p190-A; p190ARHOGAP; p190RhoGAP; rho GAP p190A; Rho GTPase activating protein 35; rho GTPase-activating protein 35; Rho-GAP protein; p190-A; GRLF1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2909

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NRY4

Gene Symbols

ARHGAP35

Immunogen

Recombinant protein corresponding to Human p190-A RhoGAP

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PNDHNVVSMP PAADVKHTYT SWDLEDMEKY RMQSIRRESR ARQKVKGPVM SQYDNMTPAV QDDLGGIYVI HLRSKSDPGK TGLLSVAEGK Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 94%
  • RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division
  • Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes
  • The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in malignant cells in vivo, such as ovarian carcinomas
  • TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of malignant cells
  • The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (TFIIIB90, BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells
  • In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA563970

--


Antigen:
GRF-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGAP35

Gene Alias:
6430596G11Rik; AI841135; ARHGAP35; GAP-associated protein p190; glucocorticoid receptor DNA binding factor 1; Glucocorticoid receptor DNA-binding factor 1; Glucocorticoid receptor repression factor 1; GRF1; GRF-1; GRLF1; KIAA1722; LOW QUALITY PROTEIN: rho GTPase-activating protein 35; MGC10745; mKIAA1722; P190 RhoGAP; P190A; p190-A; p190ARHOGAP; p190RhoGAP; rho GAP p190A; Rho GTPase activating protein 35; rho GTPase-activating protein 35; Rho-GAP protein; p190-A; GRLF1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2909

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NRY4

Gene Symbols:
ARHGAP35

Immunogen:
Recombinant protein corresponding to Human p190-A RhoGAP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA563971

--


Antigen:
ENO4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ENO4

Gene Alias:
2-phospho-D-glycerate hydro-lyase; 6430537H07Rik; C10orf134; Eno4; Enolase 4; enolase family member 4; enolase-like protein C10orf134 homolog; enolase-like protein ENO4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
387712

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
A6NNW6

Gene Symbols:
ENO4

Immunogen:
Recombinant protein corresponding to Human ENO4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA563973

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Antigen:
RANBP3L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RANBP3L

Gene Alias:
C130037N17Rik; RAN binding protein 3 like; RAN binding protein 3-like; ran-binding protein 3-like; Ranbp3l

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
202151

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q86VV4

Gene Symbols:
RANBP3L

Immunogen:
Recombinant protein corresponding to Human RANBP3L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA563975

--


Antigen:
PPP1R3E

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPP1R3E

Gene Alias:
PPP1R3E; Protein phosphatase 1 regulatory subunit 3E; protein phosphatase 1, regulatory (inhibitor) subunit 3E; protein phosphatase 1, regulatory subunit 3E

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
90673

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H7J1

Gene Symbols:
PPP1R3E

Immunogen:
Recombinant protein corresponding to Human PPP1R3E

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG