PIPA564480
Phospho-BACE1 (Ser498) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA564480-Each-of-1 | In Stock | ₹ 45,218.46 |
PIPA564480 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
Phospho-BACE1 (Ser498)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BACE1
Gene Alias
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23621, 23821, 29392
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P56817, P56818, P56819
Gene Symbols
BACE1
Immunogen
A synthesized peptide derived from human BACE (Phospho-Ser498)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Phospho-BACE1 (Ser498) Polyclonal Antibody detects endogenous levels of BACE1 only when phosphorylated at Ser498
- BACE1 (beta-secretase) is a key enzyme involved in the production of amyloid beta-peptides (Abeta) found in extracellular amyloid plaques of Alzheimer's disease (AD)
- In some cases early onset familial AD can be attributed to a "Swedish" mutation in the amyloid precursor protein (APP), which dramatically enhances the cleavage of this protein by BACE1
- This and other genetic and pathological evidence has led to therapeutic approaches that have focused on the inhibition of BACE1 and other APP-cleaving enzymes, such as gamma-secretase stuff
- APP is first cleaved by b-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99)
- The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-b peptide, which is deposited in the brains of all sufferers of Alzheimer's disease
- The long-sought b-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2)
- bACE/Asp2 is a novel transmembrane aspartic protease and colocalizes with APP.
Compare Similar Items
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Antigen: Phospho-BACE1 (Ser498)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BACE1
Gene Alias: APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23621, 23821, 29392
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P56817, P56818, P56819
Gene Symbols: BACE1
Immunogen: A synthesized peptide derived from human BACE (Phospho-Ser498)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-BACE1 (Ser498)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BACE1
Gene Alias:
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23621, 23821, 29392
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P56817, P56818, P56819
Gene Symbols:
BACE1
Immunogen:
A synthesized peptide derived from human BACE (Phospho-Ser498)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CDK4 (Thr172)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cdk4
Gene Alias: Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1019, 12567, 94201
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P11802, P30285, P35426
Gene Symbols: Cdk4
Immunogen: A synthesized peptide derived from human CDK4 (Phospho-Thr172)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CDK4 (Thr172)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cdk4
Gene Alias:
Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1019, 12567, 94201
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P11802, P30285, P35426
Gene Symbols:
Cdk4
Immunogen:
A synthesized peptide derived from human CDK4 (Phospho-Thr172)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MYL9/MYL12 (Thr17, Ser18)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYL12B
Gene Alias: 1500001M02Rik; 20 kDa myosin light chain; 2900073G15Rik; AI327049; AI838292; brain specific myosin regulatory light chain; C77744; C80200; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC2; MLC-2; MLC20; MLC-2A; MLC-2B; MLC-2C; MLCB; MLC-B; MRCL3; MRLC1; Mrlc2; MRLC3; Mrlcb; Myl12a; MYL12B; MYL2B; MYL9; MYLC2B; Mylc2c; myosin light chain 12A; myosin light chain 12B; myosin light chain 9; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; myosin regulatory light chain RLC-A; myosin regulatory light chain-B; myosin regulatory light polypeptide 9; Myosin RLC; myosin RLC-A; Myosin RLC-B; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light chain 12B, regulatory; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); MYRL2; NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; RLC-B; RLC-C; SHUJUN-1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 103910, 10398, 10627, 296313, 501203, 50685, 67268, 67938, 98932
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O14950, P13832, P18666, P19105, P24844, Q3THE2, Q64122, Q9CQ19
Gene Symbols: MYL12A, MYL12B, MYL9
Immunogen: A synthesized peptide derived from human MLC-2 (Phospho-Thr17+Ser18)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MYL9/MYL12 (Thr17, Ser18)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYL12B
Gene Alias:
1500001M02Rik; 20 kDa myosin light chain; 2900073G15Rik; AI327049; AI838292; brain specific myosin regulatory light chain; C77744; C80200; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC2; MLC-2; MLC20; MLC-2A; MLC-2B; MLC-2C; MLCB; MLC-B; MRCL3; MRLC1; Mrlc2; MRLC3; Mrlcb; Myl12a; MYL12B; MYL2B; MYL9; MYLC2B; Mylc2c; myosin light chain 12A; myosin light chain 12B; myosin light chain 9; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; myosin regulatory light chain RLC-A; myosin regulatory light chain-B; myosin regulatory light polypeptide 9; Myosin RLC; myosin RLC-A; Myosin RLC-B; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light chain 12B, regulatory; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); MYRL2; NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; RLC-B; RLC-C; SHUJUN-1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
103910, 10398, 10627, 296313, 501203, 50685, 67268, 67938, 98932
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O14950, P13832, P18666, P19105, P24844, Q3THE2, Q64122, Q9CQ19
Gene Symbols:
MYL12A, MYL12B, MYL9
Immunogen:
A synthesized peptide derived from human MLC-2 (Phospho-Thr17+Ser18)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NFATC2 (Ser326)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NFATC2
Gene Alias: AI607462; IB-IXL; KIAA0611; NFAT pre-existing s; NFAT pre-existing subunit; NFAT transcription complex, preexisting component; Nfat1; NFAT1-D; Nfatc2; NF-ATc2; Nfatp; NF-ATp; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2; nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, preexisting component; OTTHUMP00000031291; preexisting nuclear factor of activated T-cells 2; T cell transcription factor NFAT1; T-cell transcription factor NFAT1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18019, 4773
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q13469, Q60591
Gene Symbols: NFATC2
Immunogen: A synthesized peptide derived from human NFAT1 (Phospho-Ser326)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NFATC2 (Ser326)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NFATC2
Gene Alias:
AI607462; IB-IXL; KIAA0611; NFAT pre-existing s; NFAT pre-existing subunit; NFAT transcription complex, preexisting component; Nfat1; NFAT1-D; Nfatc2; NF-ATc2; Nfatp; NF-ATp; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2; nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, preexisting component; OTTHUMP00000031291; preexisting nuclear factor of activated T-cells 2; T cell transcription factor NFAT1; T-cell transcription factor NFAT1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18019, 4773
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q13469, Q60591
Gene Symbols:
NFATC2
Immunogen:
A synthesized peptide derived from human NFAT1 (Phospho-Ser326)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG