Phospho-PAK4/6/7 (Ser474) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA564495-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA564495 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
Phospho-PAK4/6/7 (Ser474)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pak4
Gene Alias
2900083L08Rik; 4732456M09; 5730488L07Rik; 6430627N20; AW555722; KIAA1142; KIAA1264; mKIAA1142; p21 (CDKN1A)-activated kinase 4; p21 (CDKN1A)-activated kinase 6; p21 (CDKN1A)-activated kinase 7; p21 (RAC1) activated kinase 4; p21 (RAC1) activated kinase 5; p21 (RAC1) activated kinase 6; p21 (RAC1) activated kinase 7; p21 protein (Cdc42/Rac)-activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 7; p21(CDKN1A)-activated kinase 4; p21(CDKN1A)-activated kinase 6; p21(CDKN1A)-activated kinase 7; p21-activated kinase 4; p21-activated kinase 5; p21-activated kinase 6; p21-activated kinase 7; p21CDKN1A-activated kinase 7; PAK4; PAK-4; PAK5; PAK-5; PAK6; PAK-6; Pak7; PAK-7; protein kinase PAK5; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; serine/threonine-protein kinase PAK 4; Serine/threonine-protein kinase PAK 5; serine/threonine-protein kinase PAK 6; serine/threonine-protein kinase PAK 6-like; serine/threonine-protein kinase PAK 7; serine/threonine-protein kinase PAK7
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10298, 214230, 241656, 292756, 296078, 311450, 56924, 57144, 70584
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
D4A280, O96013, Q3ULB5, Q8BTW9, Q8C015, Q9NQU5, Q9P286
Gene Symbols
Pak4, PAK5, PAK6, Pak7
Immunogen
A synthesized peptide derived from human PAK4/5/6 (Phospho-Ser474)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Phospho-PAK4/PAK5/PAK6 (Ser474) Polyclonal Antibody detects endogenous levels of PAK4/PAK5/PAK6 only when phosphorylated at Ser474
- PAK4 is highly expressed in prostate, testis and colon
- PAK4 interacts tightly with GTP-bound but not GDP-bound CDC42 and weakly with RAC
- PAK4 phosphorylates and autophosphorylates and also activates the JNK pathway
- PAK5, a member of the PAK family of protein kinases contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus
- PAK5 preferentially binds to CDC42 in the presence of GTP and the CRIB motif is essential for this interaction
- PAK6 protein cotranslocates into the nucleus with androgen receptor, which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development, in response to androgen
- PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues
- Later experiments have shown it to be activated by MAP kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.
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Antigen: Phospho-PAK4/6/7 (Ser474)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pak4
Gene Alias: 2900083L08Rik; 4732456M09; 5730488L07Rik; 6430627N20; AW555722; KIAA1142; KIAA1264; mKIAA1142; p21 (CDKN1A)-activated kinase 4; p21 (CDKN1A)-activated kinase 6; p21 (CDKN1A)-activated kinase 7; p21 (RAC1) activated kinase 4; p21 (RAC1) activated kinase 5; p21 (RAC1) activated kinase 6; p21 (RAC1) activated kinase 7; p21 protein (Cdc42/Rac)-activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 7; p21(CDKN1A)-activated kinase 4; p21(CDKN1A)-activated kinase 6; p21(CDKN1A)-activated kinase 7; p21-activated kinase 4; p21-activated kinase 5; p21-activated kinase 6; p21-activated kinase 7; p21CDKN1A-activated kinase 7; PAK4; PAK-4; PAK5; PAK-5; PAK6; PAK-6; Pak7; PAK-7; protein kinase PAK5; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; serine/threonine-protein kinase PAK 4; Serine/threonine-protein kinase PAK 5; serine/threonine-protein kinase PAK 6; serine/threonine-protein kinase PAK 6-like; serine/threonine-protein kinase PAK 7; serine/threonine-protein kinase PAK7
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10298, 214230, 241656, 292756, 296078, 311450, 56924, 57144, 70584
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: D4A280, O96013, Q3ULB5, Q8BTW9, Q8C015, Q9NQU5, Q9P286
Gene Symbols: Pak4, PAK5, PAK6, Pak7
Immunogen: A synthesized peptide derived from human PAK4/5/6 (Phospho-Ser474)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: Phospho-PKC beta (Ser660)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRKCB
Gene Alias: A130082F03Rik; PKCB; PKC-B; PKC-beta; PRKCB; PRKCB1; PRKCB2; protein kinase C beta; protein kinase C beta I; protein kinase C beta II; protein kinase C beta type; protein kinase C beta-II; protein kinase C, beta; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18751
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P68404
Gene Symbols: PRKCB
Immunogen: A synthesized peptide derived from human PKC beta (Phospho-Ser660)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen: Phospho-TLK1 (Ser764)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TLK1
Gene Alias: 4930545J15Rik; E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG; ESG1; GRG1; KIAA0137; PKU beta; PKU-beta; serine threonine protein kinase; serine/threonine-protein kinase tousled-like 1; SNAK; SNARE protein kinase SNAK; TLE1; TLK1; TLK-1; TLK1B; tousled like kinase 1; tousled-like kinase 1; transducin like enhancer of split 1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer protein 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 228012, 9874
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8C0V0, Q9UKI8
Gene Symbols: TLK1
Immunogen: A synthesized peptide derived from human TLK1 (Phospho-Ser764)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG