PIPA564515

Phospho-SMAD2 (Ser245) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA564515-Each-of-1 In Stock ₹ 44,705.10

PIPA564515 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-SMAD2 (Ser245)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SMAD2

Gene Alias

7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17126, 29357, 4087

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O70436, Q15796, Q62432

Gene Symbols

SMAD2

Immunogen

A synthesized peptide derived from human Smad2 (Phospho-Ser245)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Phospho-SMAD2 (Ser245) Polyclonal Antibody detects endogenous levels of SMAD2 only when phosphorylated at Ser245
  • SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
  • SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
  • Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
  • In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
  • The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
  • The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
  • SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
  • Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA564515

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Antigen:
Phospho-SMAD2 (Ser245)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17126, 29357, 4087

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70436, Q15796, Q62432

Gene Symbols:
SMAD2

Immunogen:
A synthesized peptide derived from human Smad2 (Phospho-Ser245)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA564516

--


Antigen:
Phospho-Syndecan 4 (Ser179)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Sdc4

Gene Alias:
AA959608; Amphiglycan; AW108331; MGC22217; RATRYUDOCA; RYUDOCA; ryudocan; ryudocan amphiglycan; ryudocan core protein; Ryudocan/syndecan 4; S4; SDC4; Synd4; syndecan 4; syndecan 4 (amphiglycan, ryudocan); syndecan proteoglycan 4; syndecan-4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20971, 24771, 6385

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O35988, P31431, P34901

Gene Symbols:
Sdc4

Immunogen:
A synthesized peptide derived from human Syndecan4 (Phospho-Ser179)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA564518

--


Antigen:
Phospho-HAND1 (Ser98)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HAND1

Gene Alias:
bHLHa27; Class A basic helix-loop-helix protein 27; eHAND; Ehand1; extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1; HAND1; heart and neural crest derivatives expressed 1; heart and neural crest derivatives expressed transcript 1; heart- and neural crest derivatives-expressed protein 1; Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast; Hxt; Th1; Thing1; thing-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15110, 59112, 9421

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O96004, P97832, Q64279

Gene Symbols:
HAND1

Immunogen:
A synthesized peptide derived from human HAND1 (Phospho-Ser98)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA564519

--


Antigen:
Phospho-HIC5 (Tyr60)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tgfb1i1

Gene Alias:
Androgen receptor coactivator 55 kDa protein; androgen receptor coactivator ARA55; androgen receptor-associated protein of 55 kDa; Ara55; Hic5; hic-5; hydrogen peroxide-inducible clone 5 protein; hydrogen peroxide-inducible clone-5; TGF beta-stimulated clone 5; Tgfb1i1; transforming growth factor beta 1 induced transcript 1; transforming growth factor beta-1-induced transcript 1 protein; TSC-5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21804, 7041, 84574

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43294, Q62219, Q99PD6

Gene Symbols:
Tgfb1i1

Immunogen:
A synthesized peptide derived from human Hic-5 (Phospho-Tyr60)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG