PIPA564599

Phospho-ARK5 (Ser600) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA564599-Each-of-1 In Stock ₹ 44,705.10

PIPA564599 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-ARK5 (Ser600)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NUAK1

Gene Alias

AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

77976, 9891

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O60285, Q641K5

Gene Symbols

NUAK1

Immunogen

A synthesized peptide derived from human NuaK1 (Phospho-Ser600)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Phospho-ARK5 (Ser600) Polyclonal Antibody detects endogenous levels of ARK5 only when phosphorylated at Ser600
  • NUAK1 (ARK5) is a serine/threonine kinase that plays a role in many cellular functions
  • The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm)
  • Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability
  • Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex
  • Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1
  • May be involved in DNA damage response: phosphorylates p53/TP53 at 'Ser-15' and 'Ser-392' and is recruited to the CDKN1A/WAF1 promoter to participate in transcription activation by p53/TP53
  • May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1
  • Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR
  • Regulates UV radiation-induced DNA damage response mediated by CDKN1A
  • In association with STK11, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA564599

--


Antigen:
Phospho-ARK5 (Ser600)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUAK1

Gene Alias:
AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
77976, 9891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60285, Q641K5

Gene Symbols:
NUAK1

Immunogen:
A synthesized peptide derived from human NuaK1 (Phospho-Ser600)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA564604

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Antigen:
Phospho-PDGFRB (Tyr579, Tyr581)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdgfrb

Gene Alias:
AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18596, 24629, 5159

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P05622, P09619, Q05030

Gene Symbols:
Pdgfrb

Immunogen:
A synthesized peptide derived from human PDGFRb (Phospho-Tyr579+Tyr581)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA564607

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Antigen:
Phospho-SIK2 (Thr175, Thr163)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIK2

Gene Alias:
G630080D20Rik; KIAA0781; LOH11CR1I; QIK; Qin-induced kinase; RGD1559698; salt induceable kinase 2; salt inducible kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; SIK-2; SNF1-like kinase 2; SNF1LK2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23235, 235344, 315649

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8CFH6, Q9H0K1

Gene Symbols:
SIK2

Immunogen:
A synthesized peptide derived from human QIK/QSK (Phospho-Thr182/Thr175/Thr221).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA564610

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Antigen:
Phospho-SIK1 (Thr182)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIK1

Gene Alias:
EIEE30; HRT-20; Kid2; MSK; Myocardial SNF1-like kinase; Probable serine/threonine protein kinase SNF1LK (HRT-20) (Myocardial SNF1-like kinase); protein kinase KID2; salt inducible kinase 1; salt-inducible kinase 1; salt-inducible protein kinase 1; serine/threonine protein kinase; serine/threonine-protein kinase SIK1; Serine/threonine-protein kinase SNF1-like kinase 1; serine/threonine-protein kinase SNF1LK; SIK; Sik1; SIK-1; SNF1-like kinase; SNF1LK

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
150094, 59329

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P57059, Q9R1U5

Gene Symbols:
SIK1

Immunogen:
A synthesized peptide derived from human SIK (Phospho-Thr182)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG