PIPA564733
Phospho-ACK1 (Tyr857, Tyr858) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA564733-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA564733 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
Phospho-ACK1 (Tyr857, Tyr858)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TNK2
Gene Alias
ACK; ACK1; Ack-1; Activated CDC42 kinase 1; activated Cdc42-associated kinase 1; activated p21cdc42Hs kinase; Cdc42 GTPase-inhibiting protein; Cdgip; Non-receptor protein tyrosine kinase Ack; p21cdc42Hs; P21cdc42Hs kinase; Pyk1; Tnk2; tnk2 {ECO:0000250; tyrosine kinase non receptor 2; tyrosine kinase non-receptor protein 2; tyrosine kinase, non-receptor, 2; UniProtKB:Q07912}
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10188
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q07912
Gene Symbols
TNK2
Immunogen
A synthesized peptide derived from human Ack1 (Phospho-Tyr857+Tyr858)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Phospho-ACK1 (Tyr857, Tyr858) Polyclonal Antibody detects endogenous levels of ACK1 only when phosphorylated at Tyr857, Tyr858
- TNK2 (ACK) (activated Cdc42-associated kinase) is a non-receptor tyrosine kinase that signals downstream of Cdc42
- TNK2 is known to be involved in tumorigenesis and metastasis, particularly in prostate cancer
- Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1
- May be involved both in adult synaptic function and plasticity and in brain development
- Activates AKT1 by phosphorylating it on 'Tyr-176'
- Phosphorylates AR on 'Tyr-267' and 'Tyr-363' thereby promoting its recruitment to androgen-responsive enhancers (AREs)
- Phosphorylates WWOX on 'Tyr-287'
- Phosphorylates MCF2, thereby enhancing its activity as a guanine nucleotide exchange factor (GEF) toward Rho family proteins
- Contributes to the control of AXL receptor levels
- Confers metastatic properties on cancer cells and promotes tumor growth by negatively regulating tumor suppressor such as WWOX and positively regulating pro-survival factors such as AKT1 and AR
- Phosphorylates WASP.
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Antigen: Phospho-ACK1 (Tyr857, Tyr858)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TNK2
Gene Alias: ACK; ACK1; Ack-1; Activated CDC42 kinase 1; activated Cdc42-associated kinase 1; activated p21cdc42Hs kinase; Cdc42 GTPase-inhibiting protein; Cdgip; Non-receptor protein tyrosine kinase Ack; p21cdc42Hs; P21cdc42Hs kinase; Pyk1; Tnk2; tnk2 {ECO:0000250; tyrosine kinase non receptor 2; tyrosine kinase non-receptor protein 2; tyrosine kinase, non-receptor, 2; UniProtKB:Q07912}
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10188
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q07912
Gene Symbols: TNK2
Immunogen: A synthesized peptide derived from human Ack1 (Phospho-Tyr857+Tyr858)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ACK1 (Tyr857, Tyr858)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TNK2
Gene Alias:
ACK; ACK1; Ack-1; Activated CDC42 kinase 1; activated Cdc42-associated kinase 1; activated p21cdc42Hs kinase; Cdc42 GTPase-inhibiting protein; Cdgip; Non-receptor protein tyrosine kinase Ack; p21cdc42Hs; P21cdc42Hs kinase; Pyk1; Tnk2; tnk2 {ECO:0000250; tyrosine kinase non receptor 2; tyrosine kinase non-receptor protein 2; tyrosine kinase, non-receptor, 2; UniProtKB:Q07912}
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10188
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q07912
Gene Symbols:
TNK2
Immunogen:
A synthesized peptide derived from human Ack1 (Phospho-Tyr857+Tyr858)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-IP3 Receptor 1 (Tyr353)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Itpr1
Gene Alias: ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3<R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16438, 25262, 3708
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P11881, P29994, Q14643
Gene Symbols: Itpr1
Immunogen: A synthesized peptide derived from human IP3 Receptor (Phospho-Tyr353)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-IP3 Receptor 1 (Tyr353)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Itpr1
Gene Alias:
ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3<R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16438, 25262, 3708
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P11881, P29994, Q14643
Gene Symbols:
Itpr1
Immunogen:
A synthesized peptide derived from human IP3 Receptor (Phospho-Tyr353)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-DOK2 (Tyr345)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Dok2; Dok-2; DokR; Dok-R; dok-related protein; Downstream of tyrosine kinase 2; Frip; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; LOW QUALITY PROTEIN: docking protein 2; docking protein 2; p56 dok-2; p56(dok-2); p56DOK; p56dok-2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13449, 9046
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O60496, O70469
Gene Symbols: DOK2
Immunogen: A synthesized peptide derived from human p56 Dok-2 (Phospho-Tyr345)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-DOK2 (Tyr345)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Dok2; Dok-2; DokR; Dok-R; dok-related protein; Downstream of tyrosine kinase 2; Frip; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; LOW QUALITY PROTEIN: docking protein 2; docking protein 2; p56 dok-2; p56(dok-2); p56DOK; p56dok-2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13449, 9046
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O60496, O70469
Gene Symbols:
DOK2
Immunogen:
A synthesized peptide derived from human p56 Dok-2 (Phospho-Tyr345)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Raptor (Ser792)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RPTOR
Gene Alias: 4932417H02Rik; KIAA1303; KOG1; Mip1; mKIAA1303; p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Rap; RAPTOR; regulatory associated protein of MTOR complex 1; regulatory associated protein of MTOR, complex 1; regulatory-associated protein of mTOR; RGD1311784; RPTOR
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 57521
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8N122
Gene Symbols: RPTOR
Immunogen: A synthesized peptide derived from human Raptor (Phospho-Ser792)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Raptor (Ser792)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RPTOR
Gene Alias:
4932417H02Rik; KIAA1303; KOG1; Mip1; mKIAA1303; p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Rap; RAPTOR; regulatory associated protein of MTOR complex 1; regulatory associated protein of MTOR, complex 1; regulatory-associated protein of mTOR; RGD1311784; RPTOR
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
57521
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8N122
Gene Symbols:
RPTOR
Immunogen:
A synthesized peptide derived from human Raptor (Phospho-Ser792)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG