PIPA564773

Phospho-ATM (Ser1987) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA564773-Each-of-1 In Stock ₹ 44,705.10

PIPA564773 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-ATM (Ser1987)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATM

Gene Alias

AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11920

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q62388

Gene Symbols

ATM

Immunogen

A synthesized peptide derived from human ATM (Phospho-Ser1987)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Phospho-ATM (Ser1987) Polyclonal Antibody detects endogenous levels of ATM only when phosphorylated at Ser1987
  • Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
  • Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
  • The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
  • ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
  • The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
  • The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
  • Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
  • AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
  • Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
  • Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA564773

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Antigen:
Phospho-ATM (Ser1987)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATM

Gene Alias:
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11920

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q62388

Gene Symbols:
ATM

Immunogen:
A synthesized peptide derived from human ATM (Phospho-Ser1987)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA564777

--


Antigen:
Phospho-Connexin 43 (Ser279)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GJA1

Gene Alias:
alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2697

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17302

Gene Symbols:
GJA1

Immunogen:
A synthesized peptide derived from human Connexin 43 (Phospho-Ser279)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA564779

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Antigen:
Phospho-DAPK1 (Ser308)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAPK1

Gene Alias:
D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1612, 69635

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P53355, Q80YE7

Gene Symbols:
DAPK1

Immunogen:
A synthesized peptide derived from human DAPK1 (Phospho-Ser308)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA564780

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Antigen:
Phospho-MCK10 (Tyr796)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDR1

Gene Alias:
6030432F18; AI323681; Cak; CD167; CD167 antigen-like family member A; CD167a; Cell adhesion kinase; DAAP-278B20.1; DDR; DDR1; DDR1d; discoidin domain receptor family, member 1; discoidin domain receptor tyrosine kinase 1; discoidin receptor tyrosine kinase; Drd1; Eddr1; Epithelial discoidin domain receptor 1; epithelial discoidin domain-containing receptor 1; HGK2; mammary carcinoma kinase 10; MCK10; MCK-10; Mpk6; NEP; neuroepithelial tyrosine kinase; neurotrophic tyrosine kinase receptor type 4; neurotrophic tyrosine kinase, receptor, type 4; NTRK4; protein-tyrosine kinase 3; Protein-tyrosine kinase 3A; Protein-tyrosine kinase MPK-6; protein-tyrosine kinase PTK-3; protein-tyrosine kinase RTK-6; PTK3; PTK3A; PTK3A protein tyrosine kinase 3A; PTK3D; RTK6; TRK E; TRKE; Tyrosine kinase DDR; tyrosine-protein kinase CAK

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12305, 25678, 780

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q03146, Q08345, Q63474

Gene Symbols:
DDR1

Immunogen:
A synthesized peptide derived from human DDR1 (Phospho-Tyr796)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG