PIPA564805
Phospho-MYPT1/MYPT2 (Ser668, Ser618) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA564805-Each-of-1 | In Stock | ₹ 44,961.78 |
PIPA564805 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
Phospho-MYPT1/MYPT2 (Ser668, Ser618)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPP1R12A
Gene Alias
1200015F06Rik; 1810037O03Rik; 5730577I22Rik; 9530009M10Rik; AA792106; AI132431; AV099298; D10Ertd625e; hHS-M21A; M110; M130; MBS; MBSP; myosin binding subunit; myosin phosphatase target subunit 1; Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 1; myosin phosphatase, target subunit 2; myosin phosphatase-targeting subunit 1; Myosin phosphatase-targeting subunit 2; MYPT1; Mypt2; PP1bp55; PP-1M; PPP1R12A; Ppp1r12b; Protein phosphatase 1 regulatory subunit 12A; protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12A; protein phosphatase 1, regulatory (inhibitor) subunit 12B; protein phosphatase 1, regulatory subunit 12A; protein phosphatase 1, regulatory subunit 12B; protein phosphatase myosin-binding subunit; Protein phosphatase subunit 1M; serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110; smooth muscle myosin phosphatase myosin-binding subunit
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116670, 17931, 304813, 329251, 4659, 4660
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O14974, O60237, Q10728, Q8BG95, Q9DBR7
Gene Symbols
PPP1R12A, PPP1R12B
Immunogen
A synthesized peptide derived from human MYPT1/2 (Phospho-Ser668/Ser618)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Phospho-MYPT1/MYPT2 (Ser668, Ser618) Polyclonal Antibody detects endogenous levels of MYPT1/MYPT2 only when phosphorylated at Ser668, Ser618
- Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase
- Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho
- The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells
- The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC
- Rho-associated kinase (Rho-kinase), which is activated by GTP
- RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase
- Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC
- Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase
- Several transcript variants encoding different isoforms have been found for this gene.
Compare Similar Items
Show Difference
Antigen: Phospho-MYPT1/MYPT2 (Ser668, Ser618)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP1R12A
Gene Alias: 1200015F06Rik; 1810037O03Rik; 5730577I22Rik; 9530009M10Rik; AA792106; AI132431; AV099298; D10Ertd625e; hHS-M21A; M110; M130; MBS; MBSP; myosin binding subunit; myosin phosphatase target subunit 1; Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 1; myosin phosphatase, target subunit 2; myosin phosphatase-targeting subunit 1; Myosin phosphatase-targeting subunit 2; MYPT1; Mypt2; PP1bp55; PP-1M; PPP1R12A; Ppp1r12b; Protein phosphatase 1 regulatory subunit 12A; protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12A; protein phosphatase 1, regulatory (inhibitor) subunit 12B; protein phosphatase 1, regulatory subunit 12A; protein phosphatase 1, regulatory subunit 12B; protein phosphatase myosin-binding subunit; Protein phosphatase subunit 1M; serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110; smooth muscle myosin phosphatase myosin-binding subunit
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116670, 17931, 304813, 329251, 4659, 4660
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O14974, O60237, Q10728, Q8BG95, Q9DBR7
Gene Symbols: PPP1R12A, PPP1R12B
Immunogen: A synthesized peptide derived from human MYPT1/2 (Phospho-Ser668/Ser618)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MYPT1/MYPT2 (Ser668, Ser618)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP1R12A
Gene Alias:
1200015F06Rik; 1810037O03Rik; 5730577I22Rik; 9530009M10Rik; AA792106; AI132431; AV099298; D10Ertd625e; hHS-M21A; M110; M130; MBS; MBSP; myosin binding subunit; myosin phosphatase target subunit 1; Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 1; myosin phosphatase, target subunit 2; myosin phosphatase-targeting subunit 1; Myosin phosphatase-targeting subunit 2; MYPT1; Mypt2; PP1bp55; PP-1M; PPP1R12A; Ppp1r12b; Protein phosphatase 1 regulatory subunit 12A; protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12A; protein phosphatase 1, regulatory (inhibitor) subunit 12B; protein phosphatase 1, regulatory subunit 12A; protein phosphatase 1, regulatory subunit 12B; protein phosphatase myosin-binding subunit; Protein phosphatase subunit 1M; serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110; smooth muscle myosin phosphatase myosin-binding subunit
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116670, 17931, 304813, 329251, 4659, 4660
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O14974, O60237, Q10728, Q8BG95, Q9DBR7
Gene Symbols:
PPP1R12A, PPP1R12B
Immunogen:
A synthesized peptide derived from human MYPT1/2 (Phospho-Ser668/Ser618)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CD31 (Tyr690)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pecam1
Gene Alias: C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5175
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P16284
Gene Symbols: Pecam1
Immunogen: A synthesized peptide derived from human PECAM-1 (Phospho-Tyr690)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CD31 (Tyr690)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pecam1
Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5175
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P16284
Gene Symbols:
Pecam1
Immunogen:
A synthesized peptide derived from human PECAM-1 (Phospho-Tyr690)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-ROR1 (Tyr786)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ROR1
Gene Alias: 2810404D04Rik; dJ537F10.1; Inactive tyrosine-protein kinase transmembrane receptor ROR1; MGC99659; mRor1; neurotrophic tyrosine kinase, receptor related 1; neurotrophic tyrosine kinase, receptor-related 1; Ntrkr1; receptor tyrosine kinase like orphan receptor 1; receptor tyrosine kinase-like orphan receptor 1; RGD1559469; ROR1; T-ROR1; tyrosine-protein kinase transmembrane receptor ROR1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4919
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q01973
Gene Symbols: ROR1
Immunogen: A synthesized peptide derived from human ROR1 (Phospho-Tyr786)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ROR1 (Tyr786)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ROR1
Gene Alias:
2810404D04Rik; dJ537F10.1; Inactive tyrosine-protein kinase transmembrane receptor ROR1; MGC99659; mRor1; neurotrophic tyrosine kinase, receptor related 1; neurotrophic tyrosine kinase, receptor-related 1; Ntrkr1; receptor tyrosine kinase like orphan receptor 1; receptor tyrosine kinase-like orphan receptor 1; RGD1559469; ROR1; T-ROR1; tyrosine-protein kinase transmembrane receptor ROR1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4919
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q01973
Gene Symbols:
ROR1
Immunogen:
A synthesized peptide derived from human ROR1 (Phospho-Tyr786)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-ROR2 (Ser449)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ROR2
Gene Alias: BDB; BDB1; mRor2; neurotrophic tyrosine kinase receptor-related 2; neurotrophic tyrosine kinase, receptor related 2; neurotrophic tyrosine kinase, receptor-related 2; NTRKR2; receptor tyrosine kinase like orphan receptor 2; receptor tyrosine kinase-like orphan receptor 2; ROR2; Tyrosine-protein kinase transmembrane receptor ROR2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26564, 4920
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q01974, Q9Z138
Gene Symbols: ROR2
Immunogen: A synthesized peptide derived from human ROR2 (Phospho-Ser449)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ROR2 (Ser449)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ROR2
Gene Alias:
BDB; BDB1; mRor2; neurotrophic tyrosine kinase receptor-related 2; neurotrophic tyrosine kinase, receptor related 2; neurotrophic tyrosine kinase, receptor-related 2; NTRKR2; receptor tyrosine kinase like orphan receptor 2; receptor tyrosine kinase-like orphan receptor 2; ROR2; Tyrosine-protein kinase transmembrane receptor ROR2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26564, 4920
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q01974, Q9Z138
Gene Symbols:
ROR2
Immunogen:
A synthesized peptide derived from human ROR2 (Phospho-Ser449)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG