PIPA564996
DENND3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA564996-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA564996 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
DENND3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DENND3
Gene Alias
AI447457; DENN domain containing 3; DENN domain-containing protein 3; DENN/MADD domain containing 3; Dennd3; E030003N15Rik; KIAA0870
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22898
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
A2RUS2
Gene Symbols
DENND3
Immunogen
Recombinant Human DENND3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: PTSFLMGCHLD HFEEVSKEAD GLVLINIDHG SITYSKSTDD NVDIPDVPLL AAQTFIQRVQ SLQLHHELHA AHLLSSTDLK EGRAHRRSWQ QKLNCQIQQT T Highest antigen sequence identity to the following orthologs - mouse 81%, rat 78%
- Guanine nucleotide exchange factor (GEF) activating RAB12
- Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form (PubMed:20937701)
- Regulates autophagy in response to starvation through RAB12 activation
- Starvation leads to ULK1/2-dependent phosphorylation of Ser-472 and Ser-490, which in turn allows recruitment of 14-3-3 adapter proteins and leads to up-regulation of GEF activity towards RAB12
- Also plays a role in protein transport from recycling endosomes to lysosomes, regulating, for instance, the degradation of the transferrin receptor and of the amino acid transporter PAT4 (PubMed:20937701)
- Starvation also induces phosphorylation at Tyr-858, which leads to up-regulated GEF activity and initiates autophagy
- [UniProt]
Compare Similar Items
Show Difference
Antigen: DENND3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DENND3
Gene Alias: AI447457; DENN domain containing 3; DENN domain-containing protein 3; DENN/MADD domain containing 3; Dennd3; E030003N15Rik; KIAA0870
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22898
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: A2RUS2
Gene Symbols: DENND3
Immunogen: Recombinant Human DENND3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DENND3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DENND3
Gene Alias:
AI447457; DENN domain containing 3; DENN domain-containing protein 3; DENN/MADD domain containing 3; Dennd3; E030003N15Rik; KIAA0870
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22898
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
A2RUS2
Gene Symbols:
DENND3
Immunogen:
Recombinant Human DENND3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TEC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tec
Gene Alias: cytoplasmic tyrosine kinase, Dscr28C related; MGC126760; MGC126762; PSCTK4; TEC; tec protein tyrosine kinase; tyrosine-protein kinase Tec
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100124696, 7006
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P42680
Gene Symbols: Tec
Immunogen: Recombinant Human TEC
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TEC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tec
Gene Alias:
cytoplasmic tyrosine kinase, Dscr28C related; MGC126760; MGC126762; PSCTK4; TEC; tec protein tyrosine kinase; tyrosine-protein kinase Tec
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100124696, 7006
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P42680
Gene Symbols:
Tec
Immunogen:
Recombinant Human TEC
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RP1L1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RP1L1
Gene Alias: DCDC4B; retinitis pigmentosa 1-like 1; retinitis pigmentosa 1-like 1 protein; RP1L1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 94137
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8IWN7
Gene Symbols: RP1L1
Immunogen: Recombinant Human RP1L1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RP1L1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RP1L1
Gene Alias:
DCDC4B; retinitis pigmentosa 1-like 1; retinitis pigmentosa 1-like 1 protein; RP1L1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
94137
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8IWN7
Gene Symbols:
RP1L1
Immunogen:
Recombinant Human RP1L1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: EMC4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EMC4
Gene Alias: 2610318K02Rik; Cell proliferation-inducing gene 17 protein; EMC4; ER membrane protein complex subunit 4; HSPC184; PIG17; TMEM85; Transmembrane protein 85
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51234
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q5J8M3
Gene Symbols: EMC4
Immunogen: Recombinant Human EMC4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
EMC4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EMC4
Gene Alias:
2610318K02Rik; Cell proliferation-inducing gene 17 protein; EMC4; ER membrane protein complex subunit 4; HSPC184; PIG17; TMEM85; Transmembrane protein 85
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51234
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q5J8M3
Gene Symbols:
EMC4
Immunogen:
Recombinant Human EMC4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG