PIPA565216

PKC lambda/iota Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA565216-Each-of-1 In Stock ₹ 47,015.22

PIPA565216 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

PKC lambda/iota

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRKCI

Gene Alias

2310021H13Rik; AI427505; aPKClambda; aPKC-lambda/iota; atypical protein kinase C-lambda/iota; DXS1179E; hypothetical protein; mKIAA4165; nPKC-iota; Pkci; Pkcl; PKClambda; PRKCI; Prkcl; PRKC-lambda/iota; protein kinase C iota; protein kinase C iota type; protein kinase C, iota; protein kinase C, lambda

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5584

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P41743

Gene Symbols

PRKCI

Immunogen

Recombinant Human PKC lambda/iota

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: STMSHTVAGGG SGDHSHQVRV KAYYRGDIMI THFEPSISFE GLCNEVRDMC SFDNEQLFTM KWIDEEGDPC TVSSQLEL Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%
  • The PKC family of serine/threonine kinases, including PRKCI (PKC iota), is activated intracellularly by signal transduction pathways
  • In humans, at least 12 different PKC polypeptides have been identified
  • These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
  • PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
  • The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes
  • This protein kinase is calcium-independent and phospholipid-dependent
  • It is not activated by phorbolesters or diacylglycerol
  • This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway
  • This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis
  • There is a single exon pseudogene mapped on chromosome X.

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Img

Thermo Scientific

PIPA565216

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Antigen:
PKC lambda/iota

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKCI

Gene Alias:
2310021H13Rik; AI427505; aPKClambda; aPKC-lambda/iota; atypical protein kinase C-lambda/iota; DXS1179E; hypothetical protein; mKIAA4165; nPKC-iota; Pkci; Pkcl; PKClambda; PRKCI; Prkcl; PRKC-lambda/iota; protein kinase C iota; protein kinase C iota type; protein kinase C, iota; protein kinase C, lambda

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5584

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P41743

Gene Symbols:
PRKCI

Immunogen:
Recombinant Human PKC lambda/iota

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565219

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Antigen:
IKBIP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IKBIP

Gene Alias:
1200009F10Rik; 1700023M03Rik; D18354; I kappa B kinase interacting protein; i kappa-B kinase interacting protein; i kappa-B kinase-interacting protein; Ikbip; IKBKB interacting protein; IKBKB-interacting protein; Ikip; IKK interacting protein; IKK-interacting protein; inhibitor of nuclear factor kappa-B kinase-interacting protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121457

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q70UQ0

Gene Symbols:
IKBIP

Immunogen:
Recombinant Human IKBIP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565220

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Antigen:
KIN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kin

Gene Alias:
antigenic determinant of rec-A protein; antigenic determinant of rec-A protein homolog; binding to curved DNA; Btcd; DNA/RNA-binding protein KIN17; HsKin17 protein; KIN; KIN, antigenic determinant of recA protein; KIN, antigenic determinant of recA protein homolog; KIN17; Kin17 DNA and RNA binding protein; Rts2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22944

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O60870

Gene Symbols:
Kin

Immunogen:
Recombinant Human KIN

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565221

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Antigen:
PWP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PWP1

Gene Alias:
2310058A11Rik; 2610205J09Rik; AI098170; AL022879; AV083409; AW550690; C20orf152; endonuclein; IEF-SSP-9502; Keratinocyte protein IEF SSP 9502; nuclear phosphoprotein similar to S. cerevisiae PWP1; periodic tryptophan protein 1 homolog; Pwp1; PWP1 homolog (S. cerevisiae); PWP1 homolog, endonuclein; RGD1310705

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11137

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q13610

Gene Symbols:
PWP1

Immunogen:
Recombinant Human PWP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG