PIPA565405

ALKBH2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA565405-Each-of-1 In Stock ₹ 47,015.22

PIPA565405 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

ALKBH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALKBH2

Gene Alias

2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

121642

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6NS38

Gene Symbols

ALKBH2

Immunogen

Recombinant Human ALKBH2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: DDERELAPGSP IASVSFGACR DFVFRHKDSR GKSPSRRVAV VRLPLAHGSL LMMNHPTNTH WYHSLPVRKK VLAPRVNLTF RK Highest antigen sequence identity to the following orthologs - mouse 89%, rat 88%
  • The E
  • coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA; ALKBH2 and ALKBH3 are mammalian homologs of AlkB that catalyze the removal of 1-methyladenine and 3-methylcytosine, modifications that left unchecked could lead to cancerous cells
  • Mutations in both ALKBH2 and ALKBH3 have been observed in pediatric brain tumors indicating that these proteins are important in the prevention of cancer formation
  • Like the histone demethylase JMJD1A, ALKBH2 is a non-heme iron enzyme that is inhibited by Nickel ions, suggesting that inhibition of ALKBH2 by Nickel ions may play a role in the development of cancer
  • Conversely, ALKBH2 mRNA and protein levels are increased glioma cells following Photofrin-mediated photodynamic therapy, an adjuvant therapy in cancer treatment, suggesting that down-regulating ALKBH2 expression in cancer cells may enhance the anti-cancer effectiveness of this treatment.

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Thermo Scientific

PIPA565405

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Antigen:
ALKBH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALKBH2

Gene Alias:
2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121642

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6NS38

Gene Symbols:
ALKBH2

Immunogen:
Recombinant Human ALKBH2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA565407

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Antigen:
SCAF11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCAF11

Gene Alias:
1110061H03Rik; 17D9; 2610510E10Rik; AI462454; CASP11; Caspase11; Caspase-11; CTD-associated SR protein 11; mKIAA3013; p30 subunit; protein SCAF11; Renal carcinoma antigen NY-REN-40; SC35-interacting protein 1; Scaf11; serine/arginine-rich splicing factor 2, interacting protein; serine/arginine-rich splicing factor 2-interacting protein; SFRS2-interacting protein; SFRS2IP; SIP1; splicing factor, arginine/serine-rich 2, interacting protein; splicing factor, arginine/serine-rich 2-interacting protein; Splicing regulatory protein 129; SR-related and CTD-associated factor 11; SR-related CTD associated factor 11; SR-related CTD-associated factor 11; SRrp129; SRSF2-interacting protein; SRSF2IP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9169

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q99590

Gene Symbols:
SCAF11

Immunogen:
Recombinant Human SCAF11

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA565409

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Antigen:
DGKA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dgka

Gene Alias:
80 kDa diacylglycerol kinase; 80kDa; AW146112; DAG kinase alpha; Dagk; Dagk1; Dgka; DGK-alpha; diacylglycerol kinase; diacylglycerol kinase alpha; diacylglycerol kinase alpha Flt2-Pr2; diacylglycerol kinase, alpha; diacylglycerol kinase, alpha 80kDa; Diglyceride kinase; diglyceride kinase alpha; MGC12821; MGC42356; truncated diacylglycerol kinase alpha Flt1-Pr1; truncated diacylglycerol kinase alpha Flt1-Pr2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1606

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.08 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P23743

Gene Symbols:
Dgka

Immunogen:
Recombinant Human DGKA

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA565411

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Antigen:
FAM172A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FAM172A

Gene Alias:
1110033M05Rik; 2610318O14Rik; 53-E6; 9430037D06Rik; AF064782; C5orf21; Cotranscriptional regulator FAM172A; Fam172a; family with sequence similarity 172 member A; family with sequence similarity 172, member A; LOW QUALITY PROTEIN: protein FAM172A; pEN87; Protein FAM172A; RGD1305526

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
83989

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8WUF8

Gene Symbols:
FAM172A

Immunogen:
Recombinant Human FAM172A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG