PIPA565569
GLTSCR2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA565569-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA565569 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
GLTSCR2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NOP53
Gene Alias
5330430H08Rik; 9430097C02Rik; AU041936; AW536441; glioma tumor suppressor candidate region gene 2; glioma tumor suppressor candidate region gene 2 protein; GLT; GLTSCR2; LOW QUALITY PROTEIN: glioma tumor suppressor candidate region gene 2 protein; NOP53; NOP53 ribosome biogenesis factor; p60; PICT1; PICT-1; preS1 binding protein; PreS1-binding protein; Protein interacting with carboxyl terminus 1; R74911; Ribosome biogenesis protein NOP53
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29997
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9NZM5
Gene Symbols
NOP53
Immunogen
Recombinant Human GLTSCR2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: LFFVDTGSKEK GLTKKRTKVQ KKSLLLKKPL RVDLILENTS KVPAPKDVLA HQVPNAKKLR RKEQLWEKLA Highest antigen sequence identity to the following orthologs - mouse 80%, rat 80%
- Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis
- In ribosome biogenesis, may also play a role in rRNA transcription
- Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions
- DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and allow p53/TP53 activation
- It may also positively regulate the function of p53/TP53 in cell cycle arrest and apoptosis through direct interaction, preventing its MDM2-dependent ubiquitin-mediated proteasomal degradation
- Originally identified as a tumor suppressor, it may also play a role in cell proliferation and apoptosis by positively regulating the stability of PTEN, thereby antagonizing the PI3K-AKT/PKB signaling pathway
- May also inhibit cell proliferation and increase apoptosis through its interaction with NF2
- May negatively regulate NPM1 by regulating its nucleoplasmic localization, oligomerization and ubiquitin-mediated proteasomal degradation
- Thereby, may prevent NPM1 interaction with MYC and negatively regulate transcription mediated by the MYC-NPM1 complex
- May also regulate cellular aerobic respiration
- In the cellular response to viral infection, may play a role in the attenuation of interferon-beta through the inhibition of DDX58/RIG-1.
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Antigen: GLTSCR2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NOP53
Gene Alias: 5330430H08Rik; 9430097C02Rik; AU041936; AW536441; glioma tumor suppressor candidate region gene 2; glioma tumor suppressor candidate region gene 2 protein; GLT; GLTSCR2; LOW QUALITY PROTEIN: glioma tumor suppressor candidate region gene 2 protein; NOP53; NOP53 ribosome biogenesis factor; p60; PICT1; PICT-1; preS1 binding protein; PreS1-binding protein; Protein interacting with carboxyl terminus 1; R74911; Ribosome biogenesis protein NOP53
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29997
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9NZM5
Gene Symbols: NOP53
Immunogen: Recombinant Human GLTSCR2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GLTSCR2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NOP53
Gene Alias:
5330430H08Rik; 9430097C02Rik; AU041936; AW536441; glioma tumor suppressor candidate region gene 2; glioma tumor suppressor candidate region gene 2 protein; GLT; GLTSCR2; LOW QUALITY PROTEIN: glioma tumor suppressor candidate region gene 2 protein; NOP53; NOP53 ribosome biogenesis factor; p60; PICT1; PICT-1; preS1 binding protein; PreS1-binding protein; Protein interacting with carboxyl terminus 1; R74911; Ribosome biogenesis protein NOP53
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29997
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9NZM5
Gene Symbols:
NOP53
Immunogen:
Recombinant Human GLTSCR2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TPP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TPP2
Gene Alias: TPP2; TPP-2; TppII; TPP-II; Tripeptidyl aminopeptidase; tripeptidyl peptidase 2; tripeptidyl peptidase II; tripeptidyl-peptidase 2; Tripeptidyl-peptidase II
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7174
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P29144
Gene Symbols: TPP2
Immunogen: Recombinant Human TPP2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TPP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TPP2
Gene Alias:
TPP2; TPP-2; TppII; TPP-II; Tripeptidyl aminopeptidase; tripeptidyl peptidase 2; tripeptidyl peptidase II; tripeptidyl-peptidase 2; Tripeptidyl-peptidase II
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7174
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P29144
Gene Symbols:
TPP2
Immunogen:
Recombinant Human TPP2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: C7orf25
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C7orf25
Gene Alias: C7orf25; chromosome 7 open reading frame 25; UPF0415 protein; UPF0415 protein C7orf25
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79020
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9BPX7
Gene Symbols: C7orf25
Immunogen: Recombinant Human C7orf25
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
C7orf25
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C7orf25
Gene Alias:
C7orf25; chromosome 7 open reading frame 25; UPF0415 protein; UPF0415 protein C7orf25
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79020
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9BPX7
Gene Symbols:
C7orf25
Immunogen:
Recombinant Human C7orf25
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SLC18B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLC18B1
Gene Alias: 1110021L09Rik; C6orf192; dJ55C23.6; MFS-type transporter C6orf192; MFS-type transporter C6orf192 homolog; MFS-type transporter SLC18B1; RGD1306962; SLC18B1; Solute carrier family 18 member B1; solute carrier family 18, subfamily B, member 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116843
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.4 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q6NT16
Gene Symbols: SLC18B1
Immunogen: Recombinant Human SLC18B1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SLC18B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLC18B1
Gene Alias:
1110021L09Rik; C6orf192; dJ55C23.6; MFS-type transporter C6orf192; MFS-type transporter C6orf192 homolog; MFS-type transporter SLC18B1; RGD1306962; SLC18B1; Solute carrier family 18 member B1; solute carrier family 18, subfamily B, member 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116843
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.4 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q6NT16
Gene Symbols:
SLC18B1
Immunogen:
Recombinant Human SLC18B1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG