PIPA565605

SPEN Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA565605-Each-of-1 In Stock ₹ 47,528.58

PIPA565605 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

SPEN

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPEN

Gene Alias

HIAA0929; KIAA0929; MINT; Msx2 interacting nuclear target (MINT) homolog; msx2-interacting protein; nuclear receptor transcription cofactor; RBM15C; SHARP; SMART/HDAC1-associated repressor protein; SPEN; spen family transcriptional repressor; SPEN homolog; spen homolog, transcriptional regulator

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23013

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96T58

Gene Symbols

SPEN

Immunogen

Recombinant Human SPEN

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: GEAVENQEVQS KKPIPSKPQL KQLQVLDDQG PEREDVRKNY CSLRDETPER KSGQEKSHSV NTEEKIGIDI DHTQSYRKQM EQSRRKQQME MEIAKSEKFG SPKKDVDEYE RRSLVHEVGK PPQDVTDDSP PSK Highest antigen sequence identity to the following orthologs - mouse 78%, rat 82%
  • May serve as a nuclear matrix platform that organizes and integrates transcriptional responses
  • In osteoblasts, supports transcription activation: synergizes with RUNX2 to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE)
  • Has also been shown to be an essential corepressor protein, which probably regulates different key pathways such as the Notch pathway
  • Negative regulator of the Notch pathway via its interaction with RBPSUH, which prevents the association between NOTCH1 and RBPSUH, and therefore suppresses the transactivation activity of Notch signaling
  • Blocks the differentiation of precursor B-cells into marginal zone B-cells
  • Probably represses transcription via the recruitment of large complexes containing histone deacetylase proteins
  • May bind both to DNA and RNA.

Compare Similar Items

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Img

Thermo Scientific

PIPA565605

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Antigen:
SPEN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPEN

Gene Alias:
HIAA0929; KIAA0929; MINT; Msx2 interacting nuclear target (MINT) homolog; msx2-interacting protein; nuclear receptor transcription cofactor; RBM15C; SHARP; SMART/HDAC1-associated repressor protein; SPEN; spen family transcriptional repressor; SPEN homolog; spen homolog, transcriptional regulator

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23013

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96T58

Gene Symbols:
SPEN

Immunogen:
Recombinant Human SPEN

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565609

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Antigen:
C11orf84

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C11orf84

Gene Alias:
C11orf84; chromosome 11 open reading frame 84; hypothetical protein BC007540; SPIN1-docking protein; Spindlin interactor and repressor of chromatin-binding protein; SPINDOC; SPIN-DOC; uncharacterized protein C11orf84

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
144097

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BUA3

Gene Symbols:
C11orf84

Immunogen:
Recombinant Human C11orf84

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA565611

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Antigen:
WDR88

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WDR88

Gene Alias:
PQQ repeat and WD repeat domain containing; PQQ repeat and WD repeat-containing protein; PQWD; WD repeat domain 88; WD repeat-containing protein 88; WDR88

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126248

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6ZMY6

Gene Symbols:
WDR88

Immunogen:
Recombinant Human WDR88

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA565612

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Antigen:
IRGQ

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRGQ

Gene Alias:
AF322649; FKSG27; immunity related GTPase Q; immunity-related GTPase family Q protein; immunity-related GTPase family, Q; immunity-related GTPase family, Q1; immunity-related GTPase Q; Irgq; IRGQ1; RGD1309409

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126298

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.08 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8WZA9

Gene Symbols:
IRGQ

Immunogen:
Recombinant Human IRGQ

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG