PIPA565692

ALKBH2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA565692-Each-of-1 In Stock ₹ 47,015.22

PIPA565692 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

ALKBH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALKBH2

Gene Alias

2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

121642

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6NS38

Gene Symbols

ALKBH2

Immunogen

Recombinant Human ALKBH2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LVKGAQGGLLR KQEEQEPTGE EPAVLGGDKE STRKRPRREA PGNGGHSAGP SWRHIRAEGL DCSYTVLFGK AE Highest antigen sequence identity to the following orthologs - mouse 37%, rat 40%
  • The E
  • coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA; ALKBH2 and ALKBH3 are mammalian homologs of AlkB that catalyze the removal of 1-methyladenine and 3-methylcytosine, modifications that left unchecked could lead to cancerous cells
  • Mutations in both ALKBH2 and ALKBH3 have been observed in pediatric brain tumors indicating that these proteins are important in the prevention of cancer formation
  • Like the histone demethylase JMJD1A, ALKBH2 is a non-heme iron enzyme that is inhibited by Nickel ions, suggesting that inhibition of ALKBH2 by Nickel ions may play a role in the development of cancer
  • Conversely, ALKBH2 mRNA and protein levels are increased glioma cells following Photofrin-mediated photodynamic therapy, an adjuvant therapy in cancer treatment, suggesting that down-regulating ALKBH2 expression in cancer cells may enhance the anti-cancer effectiveness of this treatment.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA565692

--


Antigen:
ALKBH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALKBH2

Gene Alias:
2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121642

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6NS38

Gene Symbols:
ALKBH2

Immunogen:
Recombinant Human ALKBH2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565693

--


Antigen:
RPL19

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPL19

Gene Alias:
60S ribosomal protein L19; DKFZp779D216; FLJ27452; HGNC:10312; L19; Large ribosomal subunit protein eL19; MGC71997; ribosomal protein L19; RPL19

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6143

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P84098

Gene Symbols:
RPL19

Immunogen:
Recombinant Human RPL19

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565694

--


Antigen:
Cullin 9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CUL9

Gene Alias:
1810035I07Rik; CUL9; CUL-9; cullin 9; cullin-9; H7AP1; KIAA0708; mKIAA0708; p53-associated parkin-like cytoplasmic protein; PARC; parkin-like cytoplasmic p53 binding protein; RP3-330M21.2; UbcH7-associated protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23113

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8IWT3

Gene Symbols:
CUL9

Immunogen:
Recombinant Human Cullin 9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565695

--


Antigen:
RAMP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ramp2

Gene Alias:
calcitonin receptor-like receptor activity modifying protein 2; calcitonin-receptor-like receptor activity-modifying protein 2; CRLR activity-modifying protein 2; OTTMUSP00000002615; OTTMUSP00000037624; Ramp2; receptor (calcitonin) activity modifying protein 2; receptor (G protein-coupled) activity modifying protein 2; receptor activity modifying protein 2; receptor activity modifying protein 2 isoform; receptor activity-modifying protein 2; receptor-activity-modifying protein 2; RP23-281C18.6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10266

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O60895

Gene Symbols:
Ramp2

Immunogen:
Recombinant Human RAMP2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG