PIPA565843

PDE6B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA565843-Each-of-1 In Stock ₹ 47,528.58

PIPA565843 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

PDE6B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PDE6B

Gene Alias

cGMP-phosphodiesterase beta-subunit; CSNB3; CSNBAD2; GMP-PDE beta; Mpb; PDE6B; PDEB; phosphodiesterase 6B; phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; phosphodiesterase 6B, cGMP-specific, rod, beta; phosphodiesterase, cGMP, rod receptor, beta polypeptide; r; rd; rd1; rd-1; rd10; retinal degeneration 1; rod cGMP-phosphodiesterase beta-subunit; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; RP40

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5158

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P35913

Gene Symbols

PDE6B

Immunogen

Recombinant Human PDE6B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: DRDEIQLILPT RARLGKEPAD CDEDELGEIL KEELPGPTTF DIYEFHFSDL Highest antigen sequence identity to the following orthologs - mouse 88%, rat 88%
  • The second messengers cAMP and cGMP are key regulatory molecules that are involved in a wide variety of signal transduction pathways
  • Levels of cAMP and cGMP are regulated by their rate of synthesis by nucleotide cyclases and by their rate of hydrolysis by cyclic nucleotide phosphodiesterases (PDEs)
  • PDEs form a superfamily of enzymes that catalyze the conversion of 3-prime, 5-prime-cyclic nucleotides to the corresponding nucleoside 5-prime-monophosphates
  • PDE6 is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system
  • There are five different subunits consisting of rod and cone specific catalytic subunits: alpha' (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family)
  • The catalytic core of the PDE6 system is comprised of alpha'/alpha' homodimers in the cone and alpha/beta heterodimers in the rod
  • The C-terminus of both the catalytic and inhibitory subunits is modified by methylation, myristyolation and prenylation which have been shown to be critical for proper complex assembly and membrane association.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA565843

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Antigen:
PDE6B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDE6B

Gene Alias:
cGMP-phosphodiesterase beta-subunit; CSNB3; CSNBAD2; GMP-PDE beta; Mpb; PDE6B; PDEB; phosphodiesterase 6B; phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; phosphodiesterase 6B, cGMP-specific, rod, beta; phosphodiesterase, cGMP, rod receptor, beta polypeptide; r; rd; rd1; rd-1; rd10; retinal degeneration 1; rod cGMP-phosphodiesterase beta-subunit; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; RP40

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5158

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P35913

Gene Symbols:
PDE6B

Immunogen:
Recombinant Human PDE6B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565844

--


Antigen:
CCHCR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCHCR1

Gene Alias:
alpha-helical coiled-coil rod protein; C6orf18; CCHCR1; Coiled-coil alpha-helical rod protein 1; HCR; HCR (a-helix coiled-coil rod homologue); pg8; Putative gene 8 protein; SBP; StAR-binding protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54535

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8TD31

Gene Symbols:
CCHCR1

Immunogen:
Recombinant Human CCHCR1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565845

--


Antigen:
MTHFS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mthfs

Gene Alias:
1110034I12Rik; 2310020H23Rik; 5, 10-methenyltetrahydrofolate synthetase; 5,10-methenyl-tetrahydrofolate synthetase; 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase); 5-formyltetrahydrofolate cyclo-ligase; AI119695; FLJ30410; HsT19268; methenyl-THF synthetase; Mthfs

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10588

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P49914

Gene Symbols:
Mthfs

Immunogen:
Recombinant Human MTHFS

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565846

--


Antigen:
ZNF212

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF212

Gene Alias:
C2H2-150; Zinc finger protein 212; Zinc finger protein C2H2-150; ZNF182; ZNF212; ZNFC150

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7988

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9UDV6

Gene Symbols:
ZNF212

Immunogen:
Recombinant Human ZNF212

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG