PIPA565967

EXOSC5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA565967-Each-of-1 In Stock ₹ 47,015.22

PIPA565967 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

EXOSC5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EXOSC5

Gene Alias

Chronic myelogenous leukemia tumor antigen 28; CML28; D7Wsu180e; EXOSC5; Exosome complex component RRP46; exosome complex exonuclease RRP46; exosome complex exonuclease RRP46; exosome complex component RRP46; exosome component 5; exosome component Rrp46; hRrp46p; p12B; Ribosomal RNA-processing protein 46; RRP41B; RRP46; Rrp46p; si:ch211-194n6.2; Unknown (protein for MGC:153707); zgc:153707

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56915

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NQT4

Gene Symbols

EXOSC5

Immunogen

Recombinant Human EXOSC5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MEEETHTDAKI RAENGTGSSP RGPGCSLRHF ACEQNLLSRP DGSASFLQGD TSVLAGVYGP AEVKVSKEI Highest antigen sequence identity to the following orthologs - mouse 80%, rat 81%
  • Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events
  • In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm
  • The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates
  • In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs
  • It seems to be involved in degradation of histone mRNA
  • The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA565967

--


Antigen:
EXOSC5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EXOSC5

Gene Alias:
Chronic myelogenous leukemia tumor antigen 28; CML28; D7Wsu180e; EXOSC5; Exosome complex component RRP46; exosome complex exonuclease RRP46; exosome complex exonuclease RRP46; exosome complex component RRP46; exosome component 5; exosome component Rrp46; hRrp46p; p12B; Ribosomal RNA-processing protein 46; RRP41B; RRP46; Rrp46p; si:ch211-194n6.2; Unknown (protein for MGC:153707); zgc:153707

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56915

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NQT4

Gene Symbols:
EXOSC5

Immunogen:
Recombinant Human EXOSC5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA565968

--


Antigen:
PLEKHG4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLEKHG4

Gene Alias:
4931414L13Rik; AI448583; ARHGEF44; mFLJ00068; PH domain-containing family G member 4; pleckstrin homology and RhoGEF domain containing G4; pleckstrin homology domain containing, family G (with RhoGef domain) member 4; Pleckstrin homology domain-containing family G member 4; PLEKHG4; PRTPHN1; Puratrophin-1; Purkinje cell atrophy associated protein 1; Purkinje cell atrophy-associated protein 1; RGD1310790; SCA4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25894

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q58EX7

Gene Symbols:
PLEKHG4

Immunogen:
Recombinant Human PLEKHG4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565969

--


Antigen:
LHX4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LHX4

Gene Alias:
A330062J17Rik; CPHD4; Gsh4; Gsh-4; Lhx4; LIM homeo box protein 4; LIM homeobox 4; LIM homeobox protein 4; LIM/homeobox protein Lhx4; LXH4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
89884

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q969G2

Gene Symbols:
LHX4

Immunogen:
Recombinant Human LHX4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA565970

--


Antigen:
PLAGL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plagl1

Gene Alias:
Lost on transformation 1; LOT1; LOT-1; PLAG1 like zinc finger 1; PLAGL1; PLAG-like 1; pleiomorphic adenoma gene-like 1; Pleiomorphic adenoma-like protein 1; Tumor suppressor ZAC; ZAC; Zac1; zinc finger protein PLAGL1; zinc finger protein regulator of apoptosis and cell cycle arrest; zinc finger protein Zac 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5325

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9UM63

Gene Symbols:
Plagl1

Immunogen:
Recombinant Human PLAGL1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG