PIPA566232
CPEB3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA566232-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA566232 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
CPEB3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cpeb3
Gene Alias
4831444O18Rik; CPEB3; CPE-binding protein 3; CPE-BP3; cytoplasmic polyadenylation element binding protein 3; cytoplasmic polyadenylation element-binding protein 3; hCPEB-3; KIAA0940; mKIAA0940; RGD1564670
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22849
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.3 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8NE35
Gene Symbols
Cpeb3
Immunogen
Recombinant Human CPEB3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: FNLHSLENSLM DMIRTDHEPL KGKHYPPSGP PMSFADIMWR NHFAGRMGIN FHHPGTDNIM ALNSRSSLFP FEDAFLDDSH GDQ Highest antigen sequence identity to the following orthologs - mouse 100%, rat 65%
- Sequence-specific RNA-binding protein which acts as a translational repressor in the basal unstimulated state but, following neuronal stimulation, acts as a translational activator
- In contrast to CPEB1, does not bind to the cytoplasmic polyadenylation element (CPE), a uridine-rich sequence element within the mRNA 3'-UTR, but binds to a U-rich loop within a stem-loop structure
- Required for the consolidation and maintenance of hippocampal-based long term memory
- In the basal state, binds to the mRNA 3'-UTR of the glutamate receptors GRIA2/GLUR2 mRNA and negatively regulates their translation
- Also represses the translation of DLG4, GRIN1, GRIN2A and GRIN2B
- When activated, acts as a translational activator of GRIA1 and GRIA2
- In the basal state, suppresses SUMO2 translation but activates it following neuronal stimulation
- Binds to the 3'-UTR of TRPV1 mRNA and represses TRPV1 translation which is required to maintain normal thermoception
- Binds actin mRNA, leading to actin translational repression in the basal state and to translational activation following neuronal stimulation
- Negatively regulates target mRNA levels by binding to TOB1 which recruits CNOT7/CAF1 to a ternary complex and this leads to target mRNA deadenylation and decay (PubMed:21336257)
- In addition to its role in translation, binds to and inhibits the transcriptional activation activity of STAT5B without affecting its dimerization or DNA-binding activity
- This, in turn, represses transcription of the STAT5B target gene EGFR which has been shown to play a role in enhancing learning and memory performance (PubMed:20639532)
- In contrast to CPEB1, CPEB2 and CPEB4, not required for cell cycle progression (PubMed:26398195)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: CPEB3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cpeb3
Gene Alias: 4831444O18Rik; CPEB3; CPE-binding protein 3; CPE-BP3; cytoplasmic polyadenylation element binding protein 3; cytoplasmic polyadenylation element-binding protein 3; hCPEB-3; KIAA0940; mKIAA0940; RGD1564670
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22849
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8NE35
Gene Symbols: Cpeb3
Immunogen: Recombinant Human CPEB3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CPEB3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cpeb3
Gene Alias:
4831444O18Rik; CPEB3; CPE-binding protein 3; CPE-BP3; cytoplasmic polyadenylation element binding protein 3; cytoplasmic polyadenylation element-binding protein 3; hCPEB-3; KIAA0940; mKIAA0940; RGD1564670
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22849
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8NE35
Gene Symbols:
Cpeb3
Immunogen:
Recombinant Human CPEB3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZNF7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZNF7
Gene Alias: C2-H2 type zinc finger protein; HF.16; KOX4; zf30; zinc finger protein 7; zinc finger protein 7 (KOX 4, clone HF.16); zinc finger protein HF.16; Zinc finger protein KOX4; zinc finger protein zfp30; Zinc finger protein-7 (KOX4); ZNF7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7553
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P17097
Gene Symbols: ZNF7
Immunogen: Recombinant Human ZNF7
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZNF7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZNF7
Gene Alias:
C2-H2 type zinc finger protein; HF.16; KOX4; zf30; zinc finger protein 7; zinc finger protein 7 (KOX 4, clone HF.16); zinc finger protein HF.16; Zinc finger protein KOX4; zinc finger protein zfp30; Zinc finger protein-7 (KOX4); ZNF7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7553
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P17097
Gene Symbols:
ZNF7
Immunogen:
Recombinant Human ZNF7
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: EXOC6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Exoc6
Gene Alias: 4833405E05Rik; AW413330; C430002C19; DKFZp761I2124; Exoc6; EXOC6A; Exocyst complex component 6; exocyst complex component Sec15A; FLJ1125; FLJ11251; hbd; MGC33397; msec15; rSec15; rsec15-like protein; Sec15; SEC15 homolog; SEC15A; SEC15L; SEC15L1; SEC15L3; SEC15-like 1; SEC15-like protein 1; SEC15-like protein 3; Sec15p; zgc:77548
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54536
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8TAG9
Gene Symbols: Exoc6
Immunogen: Recombinant Human EXOC6
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
EXOC6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Exoc6
Gene Alias:
4833405E05Rik; AW413330; C430002C19; DKFZp761I2124; Exoc6; EXOC6A; Exocyst complex component 6; exocyst complex component Sec15A; FLJ1125; FLJ11251; hbd; MGC33397; msec15; rSec15; rsec15-like protein; Sec15; SEC15 homolog; SEC15A; SEC15L; SEC15L1; SEC15L3; SEC15-like 1; SEC15-like protein 1; SEC15-like protein 3; Sec15p; zgc:77548
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54536
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8TAG9
Gene Symbols:
Exoc6
Immunogen:
Recombinant Human EXOC6
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NOD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLRC5
Gene Alias: AI451557; AK220210; Caterpiller protein 16.1; CLR16.1; copine II; Cpne2; NLR family CARD domain containing 5; NLR family, CARD domain containing 5; Nlrc5; NOD27; NOD4; NOD-like receptor C5; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5; nucleotide-binding oligomerization domains 27; protein NLRC5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84166
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q86WI3
Gene Symbols: NLRC5
Immunogen: Recombinant Human NOD4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NOD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLRC5
Gene Alias:
AI451557; AK220210; Caterpiller protein 16.1; CLR16.1; copine II; Cpne2; NLR family CARD domain containing 5; NLR family, CARD domain containing 5; Nlrc5; NOD27; NOD4; NOD-like receptor C5; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5; nucleotide-binding oligomerization domains 27; protein NLRC5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84166
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q86WI3
Gene Symbols:
NLRC5
Immunogen:
Recombinant Human NOD4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG