PIPA566293

PDE6B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA566293-Each-of-1 In Stock ₹ 47,015.22

PIPA566293 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

PDE6B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PDE6B

Gene Alias

cGMP-phosphodiesterase beta-subunit; CSNB3; CSNBAD2; GMP-PDE beta; Mpb; PDE6B; PDEB; phosphodiesterase 6B; phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; phosphodiesterase 6B, cGMP-specific, rod, beta; phosphodiesterase, cGMP, rod receptor, beta polypeptide; r; rd; rd1; rd-1; rd10; retinal degeneration 1; rod cGMP-phosphodiesterase beta-subunit; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; RP40

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5158

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P35913

Gene Symbols

PDE6B

Immunogen

Recombinant Human PDE6B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA567093

--

Img

Thermo Scientific

PIPA565973

--

Img

Thermo Scientific

PIPA567165

--

Img

Thermo Scientific

PIPA565904

--

Img

Thermo Scientific

PIPA566770

--

Img

Thermo Scientific

PIPA565986

--

Img

Thermo Scientific

PIPA566936

--

Img

Thermo Scientific

PIPA566788

--

Description

  • Immunogen sequence: MSLSEEQARSF LDQNPDFARQ YFGKKLSPEN VAAACEDGCP PDCDSLRDLC QVEEST Highest antigen sequence identity to the following orthologs - mouse 81%, rat 79%
  • The second messengers cAMP and cGMP are key regulatory molecules that are involved in a wide variety of signal transduction pathways
  • Levels of cAMP and cGMP are regulated by their rate of synthesis by nucleotide cyclases and by their rate of hydrolysis by cyclic nucleotide phosphodiesterases (PDEs)
  • PDEs form a superfamily of enzymes that catalyze the conversion of 3-prime, 5-prime-cyclic nucleotides to the corresponding nucleoside 5-prime-monophosphates
  • PDE6 is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system
  • There are five different subunits consisting of rod and cone specific catalytic subunits: alpha' (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family)
  • The catalytic core of the PDE6 system is comprised of alpha'/alpha' homodimers in the cone and alpha/beta heterodimers in the rod
  • The C-terminus of both the catalytic and inhibitory subunits is modified by methylation, myristyolation and prenylation which have been shown to be critical for proper complex assembly and membrane association.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA566293

--


Antigen:
PDE6B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDE6B

Gene Alias:
cGMP-phosphodiesterase beta-subunit; CSNB3; CSNBAD2; GMP-PDE beta; Mpb; PDE6B; PDEB; phosphodiesterase 6B; phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; phosphodiesterase 6B, cGMP-specific, rod, beta; phosphodiesterase, cGMP, rod receptor, beta polypeptide; r; rd; rd1; rd-1; rd10; retinal degeneration 1; rod cGMP-phosphodiesterase beta-subunit; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; RP40

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5158

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P35913

Gene Symbols:
PDE6B

Immunogen:
Recombinant Human PDE6B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA566296

--


Antigen:
ONECUT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ONECUT3

Gene Alias:
OC3; OC-3; One cut domain family member 3; one cut domain, family member 3; one cut homeobox 3; Onecut3; Transcription factor ONECUT-3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
390874

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O60422

Gene Symbols:
ONECUT3

Immunogen:
Recombinant Human ONECUT3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA566297

--


Antigen:
C5orf28

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM267

Gene Alias:
C5orf28; TMEM267; Transmembrane protein 267; transmembrane protein C5orf28

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64417

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q0VDI3

Gene Symbols:
TMEM267

Immunogen:
Recombinant Human C5orf28

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA566298

--


Antigen:
CNNM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNNM2

Gene Alias:
ACDP2; ancient conserved domain protein 2; ancient conserved domain-containing protein 2; AU015877; AW048635; Clp2; Cnnm2; cyclin and CBS domain divalent metal cation transport mediator 2; cyclin M2; cyclin-like protein 2; cyclin-M2; HOMG6; HOMGSMR; mACDP2; metal transporter CNNM2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54805

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H8M5

Gene Symbols:
CNNM2

Immunogen:
Recombinant Human CNNM2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG