PIPA566355

FAM21A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA566355-Each-of-1 In Stock ₹ 47,015.22

PIPA566355 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

FAM21A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WASHC2A

Gene Alias

alternative protein FAM21B; bA56A21.1; bA98I6.1; FAM21A; FAM21B; family with sequence similarity 21 member A; family with sequence similarity 21, member A; family with sequence similarity 21, member B; WASH complex subunit 2A; WASH complex subunit FAM21A; WASH complex subunit FAM21B; WASHC2A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

387680

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q641Q2

Gene Symbols

WASHC2A

Immunogen

Recombinant Human FAM21A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SVERTKPKAKI AENPANPPVG GKAKSPMFPA LGEASSDDDL FQSAKPKPAK KTNPFPLLED EDDLFTDQKV KKNE Highest antigen sequence identity to the following orthologs - mouse 51%, rat 59%
  • Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes inhibits WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization and is involved in the fission of tubules that serve as transport intermediates during endosome sorting
  • Mediates the recruitment of the WASH core complex to endosome membranes via binding to phospholipids and VPS35 of the retromer CSC
  • Mediates the recruitment of the F-actin-capping protein dimer to the WASH core complex probably promoting localized F-actin polymerization needed for vesicle scission
  • Via its C-terminus binds various phospholipids, most strongly phosphatidylinositol 4-phosphate (PtdIns-(4)P), phosphatidylinositol 5-phosphate (PtdIns-(5)P) and phosphatidylinositol 3,5-bisphosphate (PtdIns-(3,5)P2)
  • Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1
  • Required for the association of DNAJC13, ENTR1, ANKRD50 with retromer CSC subunit VPS35
  • Required for the endosomal recruitment of CCC complex subunits COMMD1 and CCDC93 as well as the retriever complex subunit VPS35L
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA566355

--


Antigen:
FAM21A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WASHC2A

Gene Alias:
alternative protein FAM21B; bA56A21.1; bA98I6.1; FAM21A; FAM21B; family with sequence similarity 21 member A; family with sequence similarity 21, member A; family with sequence similarity 21, member B; WASH complex subunit 2A; WASH complex subunit FAM21A; WASH complex subunit FAM21B; WASHC2A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
387680

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q641Q2

Gene Symbols:
WASHC2A

Immunogen:
Recombinant Human FAM21A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA566356

--


Antigen:
GDF11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GDF11

Gene Alias:
BMP11; BMP-11; bone morphogenetic protein 11; GDF11; GDF-11; growth differentiation factor 11; growth/differentiation factor 11

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10220

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O95390

Gene Symbols:
GDF11

Immunogen:
Recombinant Human GDF11

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA566360

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Antigen:
FOXL2NB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXL2NB

Gene Alias:
C3orf72; FLJ43329 protein; FOXL2 neighbor; FOXL2 neighbor protein; FOXL2NB

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
401089

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6ZUU3

Gene Symbols:
FOXL2NB

Immunogen:
Recombinant Human FOXL2NB

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA566362

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Antigen:
FAM63A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MINDY1

Gene Alias:
1810005H09Rik; 4930504E06Rik; AA562754; AA960384; AW561904; cI-40; Deubiquitinating enzyme MINDY-1; FAM63A; family with sequence similarity 63 member A; family with sequence similarity 63, member A; KIAA1390; Mindy1; mKIAA1390; NF-E2 inducible protein; Ni; Protein FAM63A; RP11-316M1.5; Ubiquitin carboxyl-terminal hydrolase MINDY-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55793

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8N5J2

Gene Symbols:
MINDY1

Immunogen:
Recombinant Human FAM63A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG