PIPA566453

SLFN11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA566453-Each-of-1 In Stock ₹ 47,015.22

PIPA566453 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SLFN11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SLFN11

Gene Alias

schlafen family member 11; SLFN11; SLFN8/9

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

91607

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q7Z7L1

Gene Symbols

SLFN11

Immunogen

Recombinant Human SLFN11

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: ETSVRSMDSRE AFCFLKTKRK PKILEEGPFH KIHKGVYQEL PNSDPADPNS DPADLIFQKD YLEYGEILP Highest antigen sequence identity to the following orthologs - mouse 41%, rat 39%
  • Inhibitor of DNA replication that promotes cell death in response to DNA damage (PubMed:22927417, PubMed:26658330, PubMed:29395061)
  • Acts as a guardian of the genome by killing cells with defective replication (PubMed:29395061)
  • Persistently blocks stressed replication forks by opening chromatin across replication initiation sites at stressed replication forks, possibly leading to unwind DNA ahead of the MCM helicase and block fork progression, μgtimately leading to cell death (PubMed:29395061)
  • Acts independently of ATR (PubMed:29395061)
  • Also acts as an interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis (PubMed:23000900)
  • Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner (PubMed:23000900)
  • Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides (PubMed:23000900)
  • The exact inhibition mechanism is unclear: may either sequester tRNAs, prevent their maturation via post-transcriptional processing or may accelerate their deacylation (PubMed:23000900)
  • Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA (PubMed:23000900)
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA566453

--


Antigen:
SLFN11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLFN11

Gene Alias:
schlafen family member 11; SLFN11; SLFN8/9

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
91607

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q7Z7L1

Gene Symbols:
SLFN11

Immunogen:
Recombinant Human SLFN11

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA566455

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Antigen:
FAM167B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FAM167B

Gene Alias:
C1orf90; FAM167B; family with sequence similarity 167 member B; family with sequence similarity 167, member B; protein FAM167B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84734

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BTA0

Gene Symbols:
FAM167B

Immunogen:
Recombinant Human FAM167B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA566456

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Antigen:
TEPP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TEPP

Gene Alias:
TEPP; testicular tissue protein Li 196; testis, prostate and placenta expressed; testis, prostate and placenta-expressed protein; testis/prostate/placenta-expressed protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
374739

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6URK8

Gene Symbols:
TEPP

Immunogen:
Recombinant Human TEPP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA566458

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Antigen:
FAM84B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FAM84B

Gene Alias:
BCMP101; BF642811; breast cancer membrane protein 101; breast cancer membrane-associated protein 101; D330050I23Rik; FAM84B; family with sequence similarity 84 member B; family with sequence similarity 84, member B; LRAT domain-containing 2; LRATD2; neurological/sensory 2; NSE2; Protein FAM84B; Protein LRATD2; Protein NSE2; RGD1562236

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
157638

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96KN1

Gene Symbols:
FAM84B

Immunogen:
Recombinant Human FAM84B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG