PIPA566706

TMEM8A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA566706-Each-of-1 In Stock ₹ 47,015.22

PIPA566706 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

TMEM8A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TMEM8A

Gene Alias

five-span transmembrane protein M83; GPI processing phospholipase A2; GPI-PLA2; M83; PGAP6; Post-GPI attachment to proteins factor 6; Protein M83; TMEM6; TMEM8; TMEM8A; Transmembrane protein 6; Transmembrane protein 8; transmembrane protein 8 (five membrane-spanning domains); transmembrane protein 8A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

58986

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9HCN3

Gene Symbols

TMEM8A

Immunogen

Recombinant Human TMEM8A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PFLGFNTSLNC TTAFFQGYPL SLSAWSRRAN LIIPYPETDN WYLSLQLMCP ENAEDCEQAV VHVETTLYLV PC Highest antigen sequence identity to the following orthologs - mouse 81%, rat 82%
  • Involved in the lipid remodeling steps of GPI-anchor maturation
  • Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchor proteins (GPI-AP)
  • Has phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI
  • Required for the shedding of the GPI-AP TDGF1, but not CFC1, at the cell surface
  • Shedding of TDGF1 modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714)
  • Also indirectly involved in the translocation of RAC1 from the cytosol to the plasma membrane by maintaining the steady state amount of CAV1-enriched plasma membrane subdomains, stabilizing RAC1 at the plasma membrane (PubMed:27835684)
  • In contrast to myomaker (TMEM8C), has no fusogenic activity (PubMed:26858401)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA566706

--


Antigen:
TMEM8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM8A

Gene Alias:
five-span transmembrane protein M83; GPI processing phospholipase A2; GPI-PLA2; M83; PGAP6; Post-GPI attachment to proteins factor 6; Protein M83; TMEM6; TMEM8; TMEM8A; Transmembrane protein 6; Transmembrane protein 8; transmembrane protein 8 (five membrane-spanning domains); transmembrane protein 8A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
58986

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9HCN3

Gene Symbols:
TMEM8A

Immunogen:
Recombinant Human TMEM8A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA566707

--


Antigen:
POLI

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Poli

Gene Alias:
DNA polymerase iota; eta2; Poli; polymerase (DNA directed) iota; polymerase (DNA directed), iota; polymerase (DNA) iota; polymerase (DNA-directed), iota; RAD 30B; RAD30; RAD30 homolog B; RAD30B; RAD3OB

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11201

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9UNA4

Gene Symbols:
Poli

Immunogen:
Recombinant Human POLI

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA566708

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Antigen:
PHF16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JADE3

Gene Alias:
5730598B06; AI851988; AW544806; jade family PHD finger 3; jade family PHD finger protein 3; JADE3; JADE-3; KIAA0215; mKIAA0215; PHD finger protein 16; PHF16; Protein Jade-3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9767

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q92613

Gene Symbols:
JADE3

Immunogen:
Recombinant Human PHF16

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA566709

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Antigen:
C20orf3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APMAP

Gene Alias:
C20orf3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57136

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9HDC9

Gene Symbols:
APMAP

Immunogen:
Recombinant Human C20orf3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG