PIPA567076
TIN2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA567076-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA567076 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
TIN2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Tinf2
Gene Alias
AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26277
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9BSI4
Gene Symbols
Tinf2
Immunogen
Recombinant Human TIN2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: FEYLCQLEKAL PTPQAQQLQD VLSWMQPGVS ITSSLAWRQY GVDMGWLLPE CSVTDSVNLA EPMEQNPPQQ QRL Highest antigen sequence identity to the following orthologs - mouse 66%, rat 61%
- TRF1 is a negative regulator of telomere length maintenance
- Recently two proteins, tankyrase and Tin2, which bind to mammalian TRF1, have been identified
- Tankyrase is a protein with homology to ankyrins as well as to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP)
- Tankyrase localizes to telomeres by binding to the telomeric repeat binding factor 1 (TRF1) through its ankyrin repeats
- Tankyrase exhibits PARP activity functioning as acceptors for adenosine diphosphate (ADP)-ribosylation
- Since ADP-ribosylation of TRF1 diminishes its ability to bind to telomeric DNA, this suggests that telomere function in human cells is regulated by poly (ADP)-ribosylation
- Both the cell cycle and TRF1 may regulate the subcellular localization of tankyrase
- The cDNA coding for TIN2 protein was isolated as interacting partner of TRF1 from a yeast two-hybrid cDNA library screening
- Tin2 localizes to telomeres and is essential for proper regulation of telomere length
- TIN2, like TRF1, is widely and constitutively expressed, suggesting that these proteins act together to counterbalance telomere elongation by telomerase
- However, endogenous TIN2, like endogenousTRF1, is not highly expressed, and therefore may be difficult to visualize by immunostaining in certain cell systems.
Compare Similar Items
Show Difference
Antigen: TIN2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tinf2
Gene Alias: AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26277
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9BSI4
Gene Symbols: Tinf2
Immunogen: Recombinant Human TIN2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TIN2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tinf2
Gene Alias:
AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26277
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9BSI4
Gene Symbols:
Tinf2
Immunogen:
Recombinant Human TIN2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TMEM92
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM92
Gene Alias: TMEM92; Transmembrane protein 92; UNQ5801/PRO19608
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 162461
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q6UXU6
Gene Symbols: TMEM92
Immunogen: Recombinant Human TMEM92
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM92
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM92
Gene Alias:
TMEM92; Transmembrane protein 92; UNQ5801/PRO19608
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
162461
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q6UXU6
Gene Symbols:
TMEM92
Immunogen:
Recombinant Human TMEM92
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SACM1L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Sacm1l
Gene Alias: Kiaa0851; mKIAA0851; phosphatidylinositide phosphatase SAC1; phosphatidylinositol-3-phosphatase SAC1; phosphatidylinositide phosphatase SAC1; phosphatidylinositol-4-phosphate phosphatase; polyphosphatidylinositol phosphatase; SAC1; SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae); SAC1 like phosphatidylinositide phosphatase; SAC1 suppressor of actin mutations 1 like; SAC1 suppressor of actin mutations 1-like (yeast); Sac1p; SACM1L; suppressor of actin 1; suppressor of actin mutations 1-like protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22908
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9NTJ5
Gene Symbols: Sacm1l
Immunogen: Recombinant Human SACM1L
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SACM1L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Sacm1l
Gene Alias:
Kiaa0851; mKIAA0851; phosphatidylinositide phosphatase SAC1; phosphatidylinositol-3-phosphatase SAC1; phosphatidylinositide phosphatase SAC1; phosphatidylinositol-4-phosphate phosphatase; polyphosphatidylinositol phosphatase; SAC1; SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae); SAC1 like phosphatidylinositide phosphatase; SAC1 suppressor of actin mutations 1 like; SAC1 suppressor of actin mutations 1-like (yeast); Sac1p; SACM1L; suppressor of actin 1; suppressor of actin mutations 1-like protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22908
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9NTJ5
Gene Symbols:
Sacm1l
Immunogen:
Recombinant Human SACM1L
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZFYVE27
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZFYVE27
Gene Alias: 2210011N02Rik; 9530077C24Rik; AI426636; AI593546; AI835681; im:7137347; LOW QUALITY PROTEIN: protrudin; PROTRUDIN; RP11-459F3.2; Spastic paraplegia 33 protein; SPG33; zfyve27; zgc:153156; zinc finger FYVE domain containing 27; zinc finger FYVE domain-containing protein 27; zinc finger FYVE-type containing 27; zinc finger, FYVE domain containing 27; zinc finger, FYVE domain containing 27 isoform c
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 118813
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q5T4F4
Gene Symbols: ZFYVE27
Immunogen: Recombinant Human ZFYVE27
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZFYVE27
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZFYVE27
Gene Alias:
2210011N02Rik; 9530077C24Rik; AI426636; AI593546; AI835681; im:7137347; LOW QUALITY PROTEIN: protrudin; PROTRUDIN; RP11-459F3.2; Spastic paraplegia 33 protein; SPG33; zfyve27; zgc:153156; zinc finger FYVE domain containing 27; zinc finger FYVE domain-containing protein 27; zinc finger FYVE-type containing 27; zinc finger, FYVE domain containing 27; zinc finger, FYVE domain containing 27 isoform c
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
118813
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q5T4F4
Gene Symbols:
ZFYVE27
Immunogen:
Recombinant Human ZFYVE27
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG