PIPA567181
ITGB1BP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA567181-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA567181 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
ITGB1BP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ITGB1BP1
Gene Alias
AI449260; AU019480; bodenin; DKFZp686K08158; Icap1; ICAP-1; ICAP1A; ICAP-1A; ICAP-1alpha; ICAP1B; ICAP-1B; integrin beta 1 binding protein 1; integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1; integrin cytoplasmic domain-associated protein 1-alpha; integrin cytoplasmic domain-associated protein 1-beta; integrin subunit beta 1 binding protein 1; ITGB1BP1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9270
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O14713
Gene Symbols
ITGB1BP1
Immunogen
Recombinant Human ITGB1BP1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SRSSTVASLDT DSTKSSGQSN NNSDTCAEFR IKYVGAIEK Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%
- Key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1
- Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis
- Stimulates cellular proliferation in a fibronectin-dependent manner
- Involved in the regulation of beta-1 integrin-containing focal adhesion (FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with talin TLN1, and hence stimulates osteoblast spreading and migration in a fibronectin-and/or collagen-dependent manner
- Acts as a guanine nucleotide dissociation inhibitor (GDI) by regulating Rho family GTPases during integrin-mediated cell matrix adhesion; reduces the level of active GTP-bound form of both CDC42 and RAC1 GTPases upon cell adhesion to fibronectin
- Stimulates the release of active CDC42 from the membranes to maintain it in an inactive cytoplasmic pool
- Participates in the translocation of the Rho-associated protein kinase ROCK1 to membrane ruffles at cell leading edges of the cell membrane, leading to an increase of myoblast cell migration on laminin
- Plays a role in bone mineralization at a late stage of osteoblast differentiation; modulates the dynamic formation of focal adhesions into fibrillar adhesions, which are adhesive structures responsible for fibronectin deposition and fibrillogenesis
- Plays a role in blood vessel development; acts as a negative regulator of angiogenesis by attenuating endothelial cell proliferation and migration, lumen formation and sprouting angiogenesis by promoting AKT phosphorylation and inhibiting ERK1/2 phosphorylation through activation of the Notch signaling pathway
- Promotes transcriptional activity of the MYC promoter.
Compare Similar Items
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Antigen: ITGB1BP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ITGB1BP1
Gene Alias: AI449260; AU019480; bodenin; DKFZp686K08158; Icap1; ICAP-1; ICAP1A; ICAP-1A; ICAP-1alpha; ICAP1B; ICAP-1B; integrin beta 1 binding protein 1; integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1; integrin cytoplasmic domain-associated protein 1-alpha; integrin cytoplasmic domain-associated protein 1-beta; integrin subunit beta 1 binding protein 1; ITGB1BP1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9270
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O14713
Gene Symbols: ITGB1BP1
Immunogen: Recombinant Human ITGB1BP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ITGB1BP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ITGB1BP1
Gene Alias:
AI449260; AU019480; bodenin; DKFZp686K08158; Icap1; ICAP-1; ICAP1A; ICAP-1A; ICAP-1alpha; ICAP1B; ICAP-1B; integrin beta 1 binding protein 1; integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1; integrin cytoplasmic domain-associated protein 1-alpha; integrin cytoplasmic domain-associated protein 1-beta; integrin subunit beta 1 binding protein 1; ITGB1BP1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9270
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O14713
Gene Symbols:
ITGB1BP1
Immunogen:
Recombinant Human ITGB1BP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FAM59B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GAREM2
Gene Alias: FAM59B; family with sequence similarity 59, member B; Garem2; Gareml; Gm444; GRB2 associated regulator of MAPK1 2; GRB2 associated regulator of MAPK1 subtype 2; GRB2 associated, regulator of MAPK1-like; GRB2-associated and regulator of MAPK protein 2; GRB2-associated and regulator of MAPK protein-like; GRB2-associated and regulator of MAPK1-like; HRIHFB2063; KIAA2038; protein FAM59B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 150946
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q75VX8
Gene Symbols: GAREM2
Immunogen: Recombinant Human FAM59B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FAM59B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GAREM2
Gene Alias:
FAM59B; family with sequence similarity 59, member B; Garem2; Gareml; Gm444; GRB2 associated regulator of MAPK1 2; GRB2 associated regulator of MAPK1 subtype 2; GRB2 associated, regulator of MAPK1-like; GRB2-associated and regulator of MAPK protein 2; GRB2-associated and regulator of MAPK protein-like; GRB2-associated and regulator of MAPK1-like; HRIHFB2063; KIAA2038; protein FAM59B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
150946
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q75VX8
Gene Symbols:
GAREM2
Immunogen:
Recombinant Human FAM59B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SLC25A46
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLC25A46
Gene Alias: 1200007B05Rik; AI325987; HMSN6B; RGD1305072; Slc25a46; Solute carrier family 25 member 46; solute carrier family 25, member 46; TB1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 91137
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q96AG3
Gene Symbols: SLC25A46
Immunogen: Recombinant Human SLC25A46
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SLC25A46
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLC25A46
Gene Alias:
1200007B05Rik; AI325987; HMSN6B; RGD1305072; Slc25a46; Solute carrier family 25 member 46; solute carrier family 25, member 46; TB1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
91137
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q96AG3
Gene Symbols:
SLC25A46
Immunogen:
Recombinant Human SLC25A46
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CHST14
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CHST14
Gene Alias: 2600016L03Rik; ATCS; carbohydrate (dermatan 4) sulfotransferase 14; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; carbohydrate sulfotransferase 14; CHST14; D4ST1; D4ST-1; dermatan 4 sulfotransferase 1; dermatan 4-sulfotransferase 1; dermatan-4-sulfotransferase-1; EDSMC1; hD4ST1; HNK1ST; UNQ1925/PRO4400
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 113189
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8NCH0
Gene Symbols: CHST14
Immunogen: Recombinant Human CHST14
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CHST14
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CHST14
Gene Alias:
2600016L03Rik; ATCS; carbohydrate (dermatan 4) sulfotransferase 14; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; carbohydrate sulfotransferase 14; CHST14; D4ST1; D4ST-1; dermatan 4 sulfotransferase 1; dermatan 4-sulfotransferase 1; dermatan-4-sulfotransferase-1; EDSMC1; hD4ST1; HNK1ST; UNQ1925/PRO4400
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
113189
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8NCH0
Gene Symbols:
CHST14
Immunogen:
Recombinant Human CHST14
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG