PIPA567326
FAM175B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA567326-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA567326 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
FAM175B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ABRAXAS2
Gene Alias
AA589499; Abraxas brother; abraxas brother 1; abraxas brother protein 1; Abraxas2; Abro1; AI853413; BRISC complex subunit Abraxas 2; BRISC complex subunit Abro1; C430003P19Rik; Em:AC068896.4; FAM175B; family with sequence similarity 175 member B; family with sequence similarity 175, member B; KIAA0157; Protein FAM175B; RGD1308918
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23172
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q15018
Gene Symbols
ABRAXAS2
Immunogen
Recombinant Human FAM175B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: VPDLVFLLFSF ISTANNSTHA LEYVLFRPNR RYNQRISLAI PNLGNTSQQE YKVSSVPNTS QSYAKVIKEH GTDFFDKDGV MKDIRAIYQV YNALQE Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%
- Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates (PubMed:19214193, PubMed:20032457, PubMed:20656690, PubMed:24075985)
- May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (PubMed:20656690)
- Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins
- Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed:26195665)
- Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression (PubMed:24075985, PubMed:26344097)
- Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed:24075985)
- Required for normal induction of p53/TP53 in response to DNA damage (PubMed:25283148)
- Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage (PubMed:25283148)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: FAM175B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABRAXAS2
Gene Alias: AA589499; Abraxas brother; abraxas brother 1; abraxas brother protein 1; Abraxas2; Abro1; AI853413; BRISC complex subunit Abraxas 2; BRISC complex subunit Abro1; C430003P19Rik; Em:AC068896.4; FAM175B; family with sequence similarity 175 member B; family with sequence similarity 175, member B; KIAA0157; Protein FAM175B; RGD1308918
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23172
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q15018
Gene Symbols: ABRAXAS2
Immunogen: Recombinant Human FAM175B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FAM175B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABRAXAS2
Gene Alias:
AA589499; Abraxas brother; abraxas brother 1; abraxas brother protein 1; Abraxas2; Abro1; AI853413; BRISC complex subunit Abraxas 2; BRISC complex subunit Abro1; C430003P19Rik; Em:AC068896.4; FAM175B; family with sequence similarity 175 member B; family with sequence similarity 175, member B; KIAA0157; Protein FAM175B; RGD1308918
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23172
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q15018
Gene Symbols:
ABRAXAS2
Immunogen:
Recombinant Human FAM175B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Astrotactin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Astn1
Gene Alias: Astn; Astn1; astrotactin 1; astrotactin-1; GC14; KIAA0289; mKIAA0289; neuronal migration protein GC14; synaptogenesis-related mRNA sequence 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 460
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O14525
Gene Symbols: Astn1
Immunogen: Recombinant Human Astrotactin
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Astrotactin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Astn1
Gene Alias:
Astn; Astn1; astrotactin 1; astrotactin-1; GC14; KIAA0289; mKIAA0289; neuronal migration protein GC14; synaptogenesis-related mRNA sequence 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
460
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O14525
Gene Symbols:
Astn1
Immunogen:
Recombinant Human Astrotactin
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CUZD1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CUZD1
Gene Alias: CUB and zona pellucida like domains 1; CUB and zona pellucida-like domain-containing protein 1; CUB and zona pellucida-like domains 1; CUB and ZP domain-containing protein 1; CUZD1; ERG1; ERG-1; estrogen regulated gene 1; ITMAP1; Transmembrane protein UO-44; UNQ224/PRO257; UO-44
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 50624
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q86UP6
Gene Symbols: CUZD1
Immunogen: Recombinant Human CUZD1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CUZD1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CUZD1
Gene Alias:
CUB and zona pellucida like domains 1; CUB and zona pellucida-like domain-containing protein 1; CUB and zona pellucida-like domains 1; CUB and ZP domain-containing protein 1; CUZD1; ERG1; ERG-1; estrogen regulated gene 1; ITMAP1; Transmembrane protein UO-44; UNQ224/PRO257; UO-44
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
50624
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q86UP6
Gene Symbols:
CUZD1
Immunogen:
Recombinant Human CUZD1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HYDIN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HYDIN
Gene Alias: CILD5; HYDIN; HYDIN, axonemal central pair apparatus protein; HYDIN1; HYDIN2; Hydrocephalus-inducing protein homolog; KIAA1864; PPP1R31; protein phosphatase 1, regulatory subunit 31
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54768
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q4G0P3
Gene Symbols: HYDIN
Immunogen: Recombinant Human HYDIN
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HYDIN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HYDIN
Gene Alias:
CILD5; HYDIN; HYDIN, axonemal central pair apparatus protein; HYDIN1; HYDIN2; Hydrocephalus-inducing protein homolog; KIAA1864; PPP1R31; protein phosphatase 1, regulatory subunit 31
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54768
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q4G0P3
Gene Symbols:
HYDIN
Immunogen:
Recombinant Human HYDIN
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG