PIPA567393

RFWD3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA567393-Each-of-1 In Stock ₹ 47,015.22

PIPA567393 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

RFWD3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RFWD3

Gene Alias

BC027246; E3 ubiquitin-protein ligase RFWD3; Rfwd3; RGD1305243; ring finger and WD repeat domain 3; RING finger and WD repeat domain-containing protein 3; RING finger protein 201; Rnf201

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55159

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6PCD5

Gene Symbols

RFWD3

Immunogen

Recombinant Human RFWD3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: NHTIPASSLHS MTNFISGLQR LHGMLEFLRP SSSNHSVGPM RTRRRVSASR RARAGGSQRT DSARLRAPLD AYFQVSRTQP DLPATTYDSE TRNPVSE Highest antigen sequence identity to the following orthologs - mouse 60%, rat 26%
  • E3 ubiquitin-protein ligase required for the repair of DNA interstrand cross-links (ICL) in response to DNA damage (PubMed:21504906, PubMed:21558276, PubMed:26474068, PubMed:28575657, PubMed:28575658)
  • Plays a key role in RPA-mediated DNA damage signaling and repair (PubMed:21504906, PubMed:21558276, PubMed:26474068, PubMed:28575657, PubMed:28575658, PubMed:28691929)
  • Acts by mediating ubiquitination of the RPA complex (RPA1, RPA2 and RPA3 subunits) and RAD51 at stalled replication forks, leading to remove them from DNA damage sites and promote homologous recombination (PubMed:26474068, PubMed:28575657, PubMed:28575658)
  • Also mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint (PubMed:20173098)
  • May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome (PubMed:20173098)
  • In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53 (PubMed:20173098)
  • [UniProt]

Compare Similar Items

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Thermo Scientific

PIPA567393

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Antigen:
RFWD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RFWD3

Gene Alias:
BC027246; E3 ubiquitin-protein ligase RFWD3; Rfwd3; RGD1305243; ring finger and WD repeat domain 3; RING finger and WD repeat domain-containing protein 3; RING finger protein 201; Rnf201

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55159

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6PCD5

Gene Symbols:
RFWD3

Immunogen:
Recombinant Human RFWD3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA567395

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Antigen:
CLTCL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLTCL1

Gene Alias:
CHC22; clathrin heavy chain 2; clathrin heavy chain like 1; clathrin heavy chain on chromosome 22; clathrin, heavy chain-like 1; Clathrin, heavy polypeptide D; clathrin, heavy polypeptide-like 1; CLH22; CLH-22; CLTCL; CLTCL1; CLTD

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8218

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P53675

Gene Symbols:
CLTCL1

Immunogen:
Recombinant Human CLTCL1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA567396

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Antigen:
ATP2C2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATP2C2

Gene Alias:
1810010G06Rik; Atp2c2; ATPase 2C2; ATPase secretory pathway Ca2+ transporting 2; ATPase, Ca++ transporting, type 2C, member 2; calcium-transporting ATPase type 2C member 2; Kiaa0703; mKIAA0703; Secretory pathway Ca(2+)-ATPase 2; secretory pathway Ca2+-ATPase; secretory pathway calcium ATPase 2; Spca2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9914

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O75185

Gene Symbols:
ATP2C2

Immunogen:
Recombinant Human ATP2C2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA567397

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Antigen:
STEAP4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STEAP4

Gene Alias:
1110021O17Rik; Ab1-219; AI481214; DKFZp666D049; dudulin 4; dudulin-4; FLJ23153; Metalloreductase STEAP4; six transmembrane prostate protein 2; six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP2; STEAP family member 4; STEAP4; STEAP4 metalloreductase; TIARP; Tnfa-induced adipose-related protein; Tnfaip9; Tumor necrosis factor, alpha-induced protein 9; tumor necrosis factor-alpha-induced adipose-related protein; tumor necrosis-alpha-induced adipose-related protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79689

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q687X5

Gene Symbols:
STEAP4

Immunogen:
Recombinant Human STEAP4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG