PIPA567508

Phospho-JAK2/JAK3 (Tyr966, Tyr939) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA567508-Each-of-1 In Stock ₹ 44,705.10

PIPA567508 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-JAK2/JAK3 (Tyr966, Tyr939)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

Breast-JAK3; fae; Fd17; JAK2; JAK-2; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; JTK10; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; THCYT3; tyrosine-protein kinase JAK2; Tyrosine-protein kinase JAK3; wil

Host Species

Rabbit

Purification Method

affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16452, 16453, 24514, 25326, 3717, 3718

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O60674, P52333, Q62120, Q62137, Q62689, Q63272

Gene Symbols

JAK2, JAK3

Immunogen

Synthesized peptide derived from human JAK2/JAK3 around the phosphorylation site of Tyr966/939.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Predicted to react with Rat samples
  • Janus Activating Kinase 2 and 3 (JAK2/JAK3) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • However, active JAK1 may be required for complex responses
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.

Compare Similar Items

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Thermo Scientific

PIPA567508

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Antigen:
Phospho-JAK2/JAK3 (Tyr966, Tyr939)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
Breast-JAK3; fae; Fd17; JAK2; JAK-2; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; JTK10; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; THCYT3; tyrosine-protein kinase JAK2; Tyrosine-protein kinase JAK3; wil

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16452, 16453, 24514, 25326, 3717, 3718

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60674, P52333, Q62120, Q62137, Q62689, Q63272

Gene Symbols:
JAK2, JAK3

Immunogen:
Synthesized peptide derived from human JAK2/JAK3 around the phosphorylation site of Tyr966/939.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA567514

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Antigen:
Phospho-Beclin 1 (Ser93, Ser96)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BECN1

Gene Alias:
4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114558, 56208, 8678

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O88597, Q14457, Q91XJ1

Gene Symbols:
BECN1

Immunogen:
Synthesized peptide derived from human Beclin 1 around the phosphorylation site of Ser93/96.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA567515

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Antigen:
Phospho-Catenin alpha-1 (Ser655, Thr658)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNNA1

Gene Alias:
[a]E-catenin; 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI988031; alpha E catenin; alpha E-catenin; alpha(E)-catenin; alpha-E-catenin; cadherin associated protein; Cadherin-associated protein; CAP102; catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha; catenin (cadherin-associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha 1; catenin alpha 1 S homeolog; catenin alpha-1; catenin, alpha 1; Catna1; cell-adhesion protein alphaE catenin; ctnna; ctnna1; ctnna1.S; MDPT2; Renal carcinoma antigen NY-REN-13; XELAEV_18020018mg

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12385, 1495

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P26231, P35221

Gene Symbols:
CTNNA1

Immunogen:
Synthesized peptide derived from human alpha Catenin around the phosphorylation site of Ser655/Thr658.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA567517

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Antigen:
Phospho-SAMHD1 (Thr592)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SAMHD1

Gene Alias:
CHBL2; DCIP; Dendritic cell-derived IFNG-induced protein; deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; E330031J07Rik; EGK_02438; HDDC1; hSAMHD1; IFN-gamma induced; interferon-gamma-inducible protein Mg11; Mg11; Mg21; Monocyte protein 5; MOP5; MOP-5; mSAMHD1; RP1-132F21.1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1; SAM domain and HD domain 1; SAM domain and HD domain, 1; SAM domain and HD domain-containing protein 1; Samhd1; SBBI88

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25939

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9Y3Z3

Gene Symbols:
SAMHD1

Immunogen:
Synthesized peptide derived from human SAMHD1 around the phosphorylation site of Thr592.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG