PIPA567526

DEDD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA567526-Each-of-1 In Stock ₹ 44,705.10

PIPA567526 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DEDD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dedd2

Gene Alias

2410050E11Rik; death effector domain containing 2; death effector domain-containing DNA binding protein 2; death effector domain-containing DNA-binding protein 2; death effector domain-containingDNA binding protein 2; DED-containing protein FLAME-3; DEDD2; DNA-binding death effector domain-containing protein 2; FADD-like anti-apoptotic molecule 3; FLAME3; FLAME-3; PSEC0004

Host Species

Rabbit

Purification Method

affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

162989

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.6 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q8WXF8

Gene Symbols

Dedd2

Immunogen

Fusion protein of human DEDD2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA560654

--

Img

Thermo Scientific

PIPA551815

--

Img

Thermo Scientific

PIPA551778

--

Img

Thermo Scientific

PIPA568399

--

Img

Thermo Scientific

PIPA551354

--

Img

Thermo Scientific

PIPA536235

--

Img

Thermo Scientific

PIPA530744

--

Img

Thermo Scientific

PIPA578260

--

Description

  • Apoptotic signals are often triggered by cell surface death receptors through protein-protein interactions mediated by conserved domains such as the death effector domain
  • A novel death effector domain (DED)-containing protein, DEDD2, has been recently identified
  • Over-expression of DEDD2 in transfected cells induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas, TRAIL, and FADD
  • More recently, it has been shown that DEDD2 can bind caspase-8 and -10 in addition to FLIP but not FADD
  • Like the related protein DEDD, DEDD2 translocates from the cytosol to the nucleus upon induction of apoptosis, and it has been suggested that DEDD2 may target caspase-8 to the nucleus and that DEDD2 thus plays a critical role in death receptor-induced apoptosis
  • At least two alternatively spliced transcript variants encoding distinct isoforms have been found for DEDD2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA567526

--


Antigen:
DEDD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dedd2

Gene Alias:
2410050E11Rik; death effector domain containing 2; death effector domain-containing DNA binding protein 2; death effector domain-containing DNA-binding protein 2; death effector domain-containingDNA binding protein 2; DED-containing protein FLAME-3; DEDD2; DNA-binding death effector domain-containing protein 2; FADD-like anti-apoptotic molecule 3; FLAME3; FLAME-3; PSEC0004

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
162989

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q8WXF8

Gene Symbols:
Dedd2

Immunogen:
Fusion protein of human DEDD2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA567527

--


Antigen:
POT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POT1

Gene Alias:
1500031H18Rik; AI505244; AI851169; CMM10; DKFZp586D211; Dolichyl-phosphate-mannose--protein mannosyltransferase 1; GLM9; HPOT1; mPot1; Pomt1; POT 1; POT1; POT-1; Pot1a; POT1-like telomere end-binding protein; protection of telomeres 1; protection of telomeres 1 homolog; protection of telomeres 1A; protection of telomeres protein 1; protein O-mannosyltransferase 1; Protein O-mannosyl-transferase 1; protein-O-mannosyltransferase 1

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25913

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9NUX5

Gene Symbols:
POT1

Immunogen:
Fusion protein of human POT1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA567528

--


Antigen:
PRL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTP4A1

Gene Alias:
AA415290; AU019864; C130021B01; DKFZp779M0721; HH72; PRL1; Prl-1; protein tyrosine phosphatase 4a1; protein tyrosine phosphatase type IVA 1; protein tyrosine phosphatase type IVA protein 1; protein tyrosine phosphatase type IVA, member 1; protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PTP(CAAX1); PTP(CAAXI); PTP4A1; PTP4A1 protein; PTP4A2; PTPCAAX1; RP5-1148A21.2

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19243, 29463, 7803

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q63739, Q78EG7, Q93096

Gene Symbols:
PTP4A1

Immunogen:
Fusion protein of human PRL1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA567530

--


Antigen:
SAA4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Saa4

Gene Alias:
amyloid A-5 protein; Constitutively expressed serum amyloid A protein; CSAA; C-SAA; Saa4; Saa-4; Saa5; Saa-5; serum amyloid A 4; serum amyloid A-4 protein; serum amyloid A4, constitutive

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6291

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.8 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P35542

Gene Symbols:
Saa4

Immunogen:
Full length Fusion protein of human SAA4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG