PIPA568016

MTCO1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA568016-Each-of-1 In Stock ₹ 44,705.10

PIPA568016 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MTCO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

mt-Co1

Gene Alias

Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1

Host Species

Rabbit

Purification Method

affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17708, 4512

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P00395, P00397

Gene Symbols

mt-Co1

Immunogen

Synthesized peptide derived from human COX1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Predicted to react with Mouse samples
  • Cytochrome c oxidase subunit I (CO1 or MTCO1) is 1 of 3 mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV
  • Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation
  • It is composed of 13 polypeptides
  • Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded
  • The cytochrome c oxidase family of enzymes have 4 redox centers, 2 hemes and 2 copper centers
  • In mitochondrial Complex IV, the 2 hemes are a and a3 and the 2 coppers are CuA and CuB
  • The 2 hemes and CuB are bound to subunit I
  • Acin-Perez et al
  • (2003) identified a cell line containing single and double missense mutations in the cytochrome c oxidase (COX) subunit I gene of mouse mitochondrial DNA
  • And they hypothesized that deleterious mutations can arise and become predominant; cultured cells can maintain several mtDNA haplotypes at stable frequencies; the respiratory chain has little spare COX capacity; and that the size of a cavity in the vicinity of val421 in MTCO1I of animal COX may affect the function of the enzyme.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA568016

--


Antigen:
MTCO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
mt-Co1

Gene Alias:
Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17708, 4512

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P00395, P00397

Gene Symbols:
mt-Co1

Immunogen:
Synthesized peptide derived from human COX1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA568017

--


Antigen:
CYP27C1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYP27C1

Gene Alias:
All-trans retinol 3,4-desaturase; CYP27C1; Cytochrome P450 27C1; cytochrome P450 family 27 subfamily C member 1; cytochrome P450, family 27, subfamily C, polypeptide 1; cytochrome P450, family 27, subfamily C, polypeptide 13

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
339761

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q4G0S4

Gene Symbols:
CYP27C1

Immunogen:
Synthesized peptide derived from human CYP27C1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA568018

--


Antigen:
COX7C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COX7C

Gene Alias:
COX7C; Cox7c1; COXVIIc; Cytochrome c oxidase polypeptide VIIc; Cytochrome c oxidase polypeptide VIIIA; cytochrome c oxidase subunit 7C; cytochrome c oxidase subunit 7C, mitochondrial; cytochrome c oxidase subunit VIIc; cytochrome c oxidase, subunit VIIc; cytochrome-c oxidase chain VIIc

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100188937, 12867, 1350

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P15954, P17665, P80432

Gene Symbols:
COX7C

Immunogen:
Synthesized peptide derived from human COX7C.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA568021

--


Antigen:
CYP46A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYP46A1

Gene Alias:
CH24H; Cholesterol 24-hydroxylase; Cholesterol 24-monooxygenase; Cholesterol 24S-hydroxylase; cholestrol 24-hydroxylase; CP46; CYP46; CYP46A1; Cytochrome P450 46A1; cytochrome P450 family 46 subfamily A member 1; cytochrome P450, 46 (cholesterol 24-hydroxylase); cytochrome P450, 46a1 (cholesterol 24-hydroxylase); cytochrome P450, family 46, subfamily A, polypeptide 1; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)

Host Species:
Rabbit

Purification Method:
affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10858, 13116

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.01% sodium azide, pH 7.3

Gene Accession No.:
Q9WVK8, Q9Y6A2

Gene Symbols:
CYP46A1

Immunogen:
Synthesized peptide derived from human CYP46A1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG