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PIPA568119

CABIN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA568119-Each-of-1 In Stock ₹ 44,705.10

PIPA568119 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CABIN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CABIN1

Gene Alias

A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor

Host Species

Rabbit

Purification Method

affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

104248, 23523, 94165

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 30% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O88480, Q9Y6J0

Gene Symbols

CABIN1

Immunogen

Synthesized peptide derived from human CABIN1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Predicted to react with Mouse and Rat samples
  • Calcineurin binding protein (Cabin-1) and the corresponding rat homolog, designated Cain, are widely expressed nuclear phosphoproteins that regulate the serine/threonine phosphotase activity of calcineurin and influence T cell signaling and apoptosis
  • Calcineurin is required for the transcriptional activation of cytokines and the activation of various transcription factors, including NFAT, NFκB and AP-1, involved in T cell receptor (TCR)-mediated signaling
  • The regulation of calcineurin depends on the changes in intracellular calcium concentrations and the activity of protein kinase C
  • TCR activation results in PKC inducing the hyperphosphorylation of Cabin-1, which facilitates the high affinity binding of Cabin-1 to calcineurin
  • This complex formation, in turn, inhibits calcineurin activity and attenuates TCR-mediated signaling
  • Cabin-1 also associates directly with MEF-2 proteins, a family of transcription factors that regulate apoptosis signaling in T cells
  • This association between Cabin-1 and MEF-2 leads to the inhibition of MEF-2-mediated gene transcription and the inhibition of apoptosis.

Compare Similar Items

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Img

Thermo Scientific

PIPA568119

--

Antigen:
CABIN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CABIN1
Gene Alias:
A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
104248, 23523, 94165
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O88480, Q9Y6J0
Gene Symbols:
CABIN1
Immunogen:
Synthesized peptide derived from human CABIN1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA568120

--

Antigen:
CABP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CABP1
Gene Alias:
Cabp1; Calbrain; calcium binding protein 1; calcium binding protein 5; calcium-binding protein 1; Caldendrin; HCALB_BR
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
171051, 29867, 9478
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O88751, Q9JLK7, Q9NZU7
Gene Symbols:
CABP1
Immunogen:
Synthesized peptide derived from human CABP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA568123

--

Antigen:
CADPS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CADPS2
Gene Alias:
A230044C21Rik; Ca++-dependent secretion activator 2; Ca2+ dependent secretion activator 2; Ca2+-dependent activator protein for secretion 2; Cadps2; calcium dependent secretion activator 2; calcium-dependent activator protein for secretion 2; Calcium-dependent secretion activator 2; calcyphosin-2; calcyphosine 2; Calcyphosine-2; calcyphosphine 2; Caps2; CAPS-2; cerebellum postnatal development associated protein 2; Cpd2; KIAA1591; RGD1559440; UG0636c06
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
93664
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q86UW7
Gene Symbols:
CADPS2
Immunogen:
Synthesized peptide derived from human CAPS2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA568124

--

Antigen:
CAMTA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CAMTA2
Gene Alias:
calmodulin binding transcription activator 2; calmodulin-binding transcription activator 2; Camta2; Kiaa0909; Kiaa0909-hp; mKIAA0909
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
216874, 23125
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O94983, Q80Y50
Gene Symbols:
CAMTA2
Immunogen:
Synthesized peptide derived from human CAMTA2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG