PIPA568153
MCU Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA568153-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA568153 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
MCU
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MCU
Gene Alias
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species
Rabbit
Purification Method
affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
215999, 90550
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q3UMR5, Q8NE86
Gene Symbols
MCU
Immunogen
Synthesized peptide derived from human MCU.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- Predicted to react with Mouse samples
- Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria
- Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex)
- Activity is regulated by MICU1 and MICU2
- At low Ca(2+) levels MCU activity is down-regulated by MICU1 and MICU2; at higher Ca(2+) levels MICU1 increases MCU activity
- Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways
- Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes
- While dispensable for baseline homeostatic cardiac function, acts as a key regulator of short-term mitochondrial calcium loading underlying a 'fight-or-flight' response during acute stress: acts by mediating a rapid increase of mitochondrial calcium in pacemaker cells
- participates in mitochondrial permeability transition during ischemia-reperfusion injury
- Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake
- Mitochondrial calcium uptake in skeletal muscle cells is involved in muscle size in adults
- Regulates synaptic vesicle endocytosis kinetics in central nerve terminal
- Involved in antigen processing and presentation.
Compare Similar Items
Show Difference
Antigen: MCU
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MCU
Gene Alias: 2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species: Rabbit
Purification Method: affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 215999, 90550
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q3UMR5, Q8NE86
Gene Symbols: MCU
Immunogen: Synthesized peptide derived from human MCU.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MCU
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MCU
Gene Alias:
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
215999, 90550
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q3UMR5, Q8NE86
Gene Symbols:
MCU
Immunogen:
Synthesized peptide derived from human MCU.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: C1QL3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C1QL3
Gene Alias: 1110065A22Rik; AI661623; C1q and tumor necrosis factor-related protein 13; C1q/TNF-related protein 13; C1ql; C1ql3; C1q-like 3; C1qtnf13; complement C1q like 3; complement C1q-like protein 3; complement component 1, q subcomponent-like 3; CTRP13; Gliacolin; K100
Host Species: Rabbit
Purification Method: affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 227580, 389941
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5VWW1, Q9ESN4
Gene Symbols: C1QL3
Immunogen: Synthesized peptide derived from human C1QL3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
C1QL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C1QL3
Gene Alias:
1110065A22Rik; AI661623; C1q and tumor necrosis factor-related protein 13; C1q/TNF-related protein 13; C1ql; C1ql3; C1q-like 3; C1qtnf13; complement C1q like 3; complement C1q-like protein 3; complement component 1, q subcomponent-like 3; CTRP13; Gliacolin; K100
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
227580, 389941
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5VWW1, Q9ESN4
Gene Symbols:
C1QL3
Immunogen:
Synthesized peptide derived from human C1QL3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: C1QL4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C1QL4
Gene Alias: C1q and tumor necrosis factor-related protein 11; C1q/TNF-related protein 11; C1ql4; C1qtnf11; complement C1q like 4; complement C1q-like protein 4; complement component 1, q subcomponent like 4; complement component 1, q subcomponent-like 4; Ctrp11
Host Species: Rabbit
Purification Method: affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 239659, 300220, 338761
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q4ZJM9, Q86Z23
Gene Symbols: C1QL4
Immunogen: Synthesized peptide derived from human C1QL4.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
C1QL4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C1QL4
Gene Alias:
C1q and tumor necrosis factor-related protein 11; C1q/TNF-related protein 11; C1ql4; C1qtnf11; complement C1q like 4; complement C1q-like protein 4; complement component 1, q subcomponent like 4; complement component 1, q subcomponent-like 4; Ctrp11
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
239659, 300220, 338761
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q4ZJM9, Q86Z23
Gene Symbols:
C1QL4
Immunogen:
Synthesized peptide derived from human C1QL4.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: DOCK7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DOCK7
Gene Alias: 3110056M06Rik; dedicator of cytokinesis 7; dedicator of cytokinesis protein 7; Dock7; EIEE23; Gm430; KIAA1771; m; protein moonlight; ZIR2
Host Species: Rabbit
Purification Method: affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 67299, 85440
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8R1A4, Q96N67
Gene Symbols: DOCK7
Immunogen: Synthesized peptide derived from human DOCK7.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
DOCK7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DOCK7
Gene Alias:
3110056M06Rik; dedicator of cytokinesis 7; dedicator of cytokinesis protein 7; Dock7; EIEE23; Gm430; KIAA1771; m; protein moonlight; ZIR2
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
67299, 85440
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8R1A4, Q96N67
Gene Symbols:
DOCK7
Immunogen:
Synthesized peptide derived from human DOCK7.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG