PIPA568232
MPP8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA568232-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA568232 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MPP8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MPHOSPH8
Gene Alias
1500035L22Rik; 4930548G07Rik; Ab2-008; AU040635; HSMPP8; M-phase phosphoprotein 8; M-phase phosphoprotein, mpp; M-phase phosphoprotein, mpp8; Mphosph8; MPP8; RGD1305133; TWA3; Two hybrid-associated protein 3 with RanBPM
Host Species
Rabbit
Purification Method
affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
290270, 54737, 75339
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
G3V8T1, Q3TYA6, Q99549
Gene Symbols
MPHOSPH8
Immunogen
Synthesized peptide derived from human MPP8.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Predicted to react with Mouse and Rat samples
- Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416)
- Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2 (PubMed:26022416, PubMed:28581500)
- Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592)
- Mediates down-regulation of CDH1 expression (PubMed:20871592)
- Also represses L1 retrotransposons in collaboration with MORC2 and, probably, SETDB1, the silencing is dependent of repressive epigenetic modifications, such as H3K9me3 mark
- Silencing events often occur within introns of transcriptionally active genes, and lead to the down-regulation of host gene expression (PubMed:29211708)
- The HUSH complex is also involved in the silencing of unintegrated retroviral DNA by being recruited by ZNF638: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed (PubMed:30487602)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: MPP8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MPHOSPH8
Gene Alias: 1500035L22Rik; 4930548G07Rik; Ab2-008; AU040635; HSMPP8; M-phase phosphoprotein 8; M-phase phosphoprotein, mpp; M-phase phosphoprotein, mpp8; Mphosph8; MPP8; RGD1305133; TWA3; Two hybrid-associated protein 3 with RanBPM
Host Species: Rabbit
Purification Method: affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 290270, 54737, 75339
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: G3V8T1, Q3TYA6, Q99549
Gene Symbols: MPHOSPH8
Immunogen: Synthesized peptide derived from human MPP8.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MPP8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MPHOSPH8
Gene Alias:
1500035L22Rik; 4930548G07Rik; Ab2-008; AU040635; HSMPP8; M-phase phosphoprotein 8; M-phase phosphoprotein, mpp; M-phase phosphoprotein, mpp8; Mphosph8; MPP8; RGD1305133; TWA3; Two hybrid-associated protein 3 with RanBPM
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
290270, 54737, 75339
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
G3V8T1, Q3TYA6, Q99549
Gene Symbols:
MPHOSPH8
Immunogen:
Synthesized peptide derived from human MPP8.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MEGF6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MEGF6
Gene Alias: 2600001P17Rik; Egfl3; EGF-like domain-containing protein 3; EGF-like protein 3; EGF-like-domain, multiple 3; Epidermal growth factor-like protein 3; KIAA0815; MEGF6; multiple EGF like domains 6; multiple EGF-like domain protein 3; multiple EGF-like domains protein 6; multiple EGF-like-domains 6; multiple epidermal growth factor-like domains 6; multiple epidermal growth factor-like domains protein 6
Host Species: Rabbit
Purification Method: affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1953, 230971, 65049
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O75095, O88281, Q80V70
Gene Symbols: MEGF6
Immunogen: Synthesized peptide derived from human MEGF6.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MEGF6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MEGF6
Gene Alias:
2600001P17Rik; Egfl3; EGF-like domain-containing protein 3; EGF-like protein 3; EGF-like-domain, multiple 3; Epidermal growth factor-like protein 3; KIAA0815; MEGF6; multiple EGF like domains 6; multiple EGF-like domain protein 3; multiple EGF-like domains protein 6; multiple EGF-like-domains 6; multiple epidermal growth factor-like domains 6; multiple epidermal growth factor-like domains protein 6
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1953, 230971, 65049
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O75095, O88281, Q80V70
Gene Symbols:
MEGF6
Immunogen:
Synthesized peptide derived from human MEGF6.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MYH3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYH3
Gene Alias: DA2A; DA2B; DA8; embryonic skeletal myosin heavy chain isoform; HEMHC; Muscle embryonic myosin heavy chain; MYH3; MyHC-emb; Myhse; Myhs-e; MYHSE1; myosin heavy chain 3; Myosin heavy chain, fast skeletal muscle, embryonic; myosin heavy polypeptide 3; myosin, heavy chain 3, skeletal muscle, embryonic; myosin, heavy polypeptide 3, skeletal muscle, embryonic; myosin, skeletal, heavy chain, embryonic 1; myosin-3; RNMHCG; SMHCE
Host Species: Rabbit
Purification Method: affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17883, 24583, 4621
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P11055, P12847, P13541
Gene Symbols: MYH3
Immunogen: Synthesized peptide derived from human MYH3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MYH3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYH3
Gene Alias:
DA2A; DA2B; DA8; embryonic skeletal myosin heavy chain isoform; HEMHC; Muscle embryonic myosin heavy chain; MYH3; MyHC-emb; Myhse; Myhs-e; MYHSE1; myosin heavy chain 3; Myosin heavy chain, fast skeletal muscle, embryonic; myosin heavy polypeptide 3; myosin, heavy chain 3, skeletal muscle, embryonic; myosin, heavy polypeptide 3, skeletal muscle, embryonic; myosin, skeletal, heavy chain, embryonic 1; myosin-3; RNMHCG; SMHCE
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17883, 24583, 4621
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P11055, P12847, P13541
Gene Symbols:
MYH3
Immunogen:
Synthesized peptide derived from human MYH3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MYO1A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYO1A
Gene Alias: BBMI; BBM-I; brush border myosin 1; brush border myosin I; brush border myosin-I; DFNA48; MIHC; Myh1; MYHL; Myo1a; myosin heavy polypeptide 1 skeletal muscle adult; myosin I heavy chain; myosin IA; myosin, heavy polypeptide-like (100kD); myosin, heavy polypeptide-like (110kD); myosin-Ia; unconventional myosin-Ia
Host Species: Rabbit
Purification Method: affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 299509, 432516, 4640
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O88329, Q62774, Q9UBC5
Gene Symbols: MYO1A
Immunogen: Synthesized peptide derived from human MYO1A.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MYO1A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYO1A
Gene Alias:
BBMI; BBM-I; brush border myosin 1; brush border myosin I; brush border myosin-I; DFNA48; MIHC; Myh1; MYHL; Myo1a; myosin heavy polypeptide 1 skeletal muscle adult; myosin I heavy chain; myosin IA; myosin, heavy polypeptide-like (100kD); myosin, heavy polypeptide-like (110kD); myosin-Ia; unconventional myosin-Ia
Host Species:
Rabbit
Purification Method:
affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
299509, 432516, 4640
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O88329, Q62774, Q9UBC5
Gene Symbols:
MYO1A
Immunogen:
Synthesized peptide derived from human MYO1A.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG