PIPA568760

CIITA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA568760-Each-of-1 In Stock ₹ 44,277.30

PIPA568760 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

CIITA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CIITA

Gene Alias

C2ta; CIITA; CIITAIV; class II major histocompatibility complex transactivator; class II transactivator; class II, major histocompatibility complex, transactivator; EG669998; Gm9475; MH NLRA; MHC class II transactivator; MHC class II transactivator type I; MHC class II transactivator type III; MHC class II transactivator type IV; MHC2TA; NLR family, acid domain containing; NLRA; nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12265

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

P79621

Gene Symbols

CIITA

Immunogen

synthetic peptide directed towards the C terminal region of mouse CIITA

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This target displays homology in the following species: Dog: 100%; Human: 79%; Mouse: 100%; Rat: 93% CIITA contains an acidic transcriptional activation domain, four LRRs (leucine-rich repeats) and a GTP binding domain
  • It is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the &quotemaster control factor&quote for the expression of these genes
  • CIITA also binds GTP and uses GTP binding to facilitate its own transport into the nucleus
  • Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion
  • Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA568760

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Antigen:
CIITA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIITA

Gene Alias:
C2ta; CIITA; CIITAIV; class II major histocompatibility complex transactivator; class II transactivator; class II, major histocompatibility complex, transactivator; EG669998; Gm9475; MH NLRA; MHC class II transactivator; MHC class II transactivator type I; MHC class II transactivator type III; MHC class II transactivator type IV; MHC2TA; NLR family, acid domain containing; NLRA; nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12265

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P79621

Gene Symbols:
CIITA

Immunogen:
synthetic peptide directed towards the C terminal region of mouse CIITA

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA568761

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Antigen:
ESX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Esx1

Gene Alias:
ESX homeobox 1; ESX1; ESX1L; ESX1R; ESX1-related protein; ESXR1; extraembryonic spermatogenesis homeobox 1; extraembryonic, spermatogenesis, homeobox 1; extraembryonic, spermatogenesis, homeobox 1 homolog; homeobox protein ESX1; Homeobox protein ESX1-C; Homeobox protein ESX1-N; RP3-513M9.1; Spx1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
80712

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8N693

Gene Symbols:
Esx1

Immunogen:
synthetic peptide directed towards the N terminal region of mouse ESX1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA568762

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Antigen:
ETV2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ETV2

Gene Alias:
ER71; ets related protein 71; ETS translocation variant 2; ETS variant 2; ets variant gene 2; ETS variant transcription factor 2; ets-related protein 71; Etsrp71; ETV2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14008

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P41163

Gene Symbols:
ETV2

Immunogen:
synthetic peptide directed towards the middle region of mouse ETV2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Antigen:
GATA5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gata5

Gene Alias:
bB379O24.1; GATA binding factor-5; GATA binding protein 5; GATA5; GATA-binding factor 5; GATA-binding protein 5; GATAS; hypothetical protein LOC504784; transcription factor GATA-5; Transcription factor GATA-5 (GATA binding factor-5)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14464

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P97489

Gene Symbols:
Gata5

Immunogen:
synthetic peptide directed towards the C terminal region of mouse GATA5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG