PIPA569443

PLA2G2E Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA569443-Each-of-1 In Stock ₹ 44,705.10

PIPA569443 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PLA2G2E

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLA2G2E

Gene Alias

GIIE sPLA2; Group IIE secretory phospholipase A2; mGIIEsPLA2s; phosphatidylcholine 2-acylhydrolase 2E; phospholipase A2 group IIE; phospholipase A2, group IIE; Pla2g2e; sPLA2-IIE

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

30814

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q9NZK7

Gene Symbols

PLA2G2E

Immunogen

synthetic peptide directed towards the middle region of human PLA2G2E

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This target displays homology in the following species: Cow: 100%; Horse: 93%; Human: 100%; Mouse: 100% Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids (PubMed:10681567, PubMed:11922621, PubMed:28883454)
  • Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), releasing various unsaturated fatty acids including oleoate, linoleoate, arachidonate, docosahexaenoate and lysophosphatidylethanolamines in preference to lysophosphatidylcholines (PubMed:10681567, PubMed:28883454)
  • In response to high-fat diet, hydrolyzes minor lipoprotein phospholipids including phosphatidylserines, phosphatidylinositols and phosphatidylglycerols, altering lipoprotein composition and fat storage in adipose tissue and liver
  • May act in an autocrine and paracrine manner (PubMed:11922621)
  • Contributes to lipid remodeling of cellular membranes and generation of lipid mediators involved in pathogen clearance
  • Cleaves sn-2 fatty acyl chains of phosphatidylglycerols and phosphatidylethanolamines, which are major components of membrane phospholipids in bacteria (PubMed:11922621)
  • Acts as a hair follicle phospholipase A2
  • Selectively releases lysophosphatidylethanolamines (LPE) and various unsaturated fatty acids in skin to regulate hair follicle homeostasis
  • May regulate the inflammatory response by releasing arachidonate, a precursor of prostaglandins and leukotrienes (PubMed:11922621)
  • Upon allergen exposure, may participate in allergic inflammatory response by enhancing leukotriene C4 synthesis and degranulation in mast cells
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA569443

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Antigen:
PLA2G2E

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLA2G2E

Gene Alias:
GIIE sPLA2; Group IIE secretory phospholipase A2; mGIIEsPLA2s; phosphatidylcholine 2-acylhydrolase 2E; phospholipase A2 group IIE; phospholipase A2, group IIE; Pla2g2e; sPLA2-IIE

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
30814

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9NZK7

Gene Symbols:
PLA2G2E

Immunogen:
synthetic peptide directed towards the middle region of human PLA2G2E

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA569444

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Antigen:
KIAA0100

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIAA0100

Gene Alias:
Antigen MLAA-22; BCOX; BCOX1; breast cancer overexpressed gene 1; breast cancer-overexpressed gene 1 protein; cancer/testis antigen 101; CT101; FMP27; K0100; KIAA0100; protein KIAA0100; U937-associated antigen

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9703

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q14667

Gene Symbols:
KIAA0100

Immunogen:
synthetic peptide directed towards the middle region of human KIAA0100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA569451

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Antigen:
DHRS7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DHRS7

Gene Alias:
2310016E22Rik; 5730564L20Rik; AW061210; CGI-86; dehydrogenase/reductase (SDR family) member 7; dehydrogenase/reductase 7; dehydrogenase/reductase SDR family member 7; Dhrs7; DHRS7A; Retdsr4; retinal short-chain dehydrogenase/reductase 4; Retsdr4; RGD1565002; SDR34C1; short chain dehydrogenase/reductase family 34C member 1; short chain dehydrogenase/reductase family 34C, member 1; similar to Dehydrogenase/reductase SDR family member 7 precursor (Retinal short-chain dehydrogenase/reductase 4); similar to Dehydrogenase/reductase SDR family member 7 precursor (Retinal short-chain dehydrogenase/reductase 4) (retSDR4); uncharacterized protein LOC299135; UNQ285/PRO3448

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
66375

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9CXR1

Gene Symbols:
DHRS7

Immunogen:
synthetic peptide corresponding to a region of mouse DHRS7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA569453

--


Antigen:
IER3IP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IER3IP1

Gene Alias:
1110057H19Rik; 796; AI644142; AL022842; AL022863; AV026606; HSPC039; IER3IP1; immediate early response 3 interacting protein 1; immediate early response 3-interacting protein 1; MEDS; PRO2309; uncharacterized protein LOC500270

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
66191

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9CR20

Gene Symbols:
IER3IP1

Immunogen:
synthetic peptide corresponding to a region of mouse IER3IP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG