PIPA570276

YTHDF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA570276-Each-of-1 In Stock ₹ 44,705.10

PIPA570276 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

YTHDF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

YTHDF1

Gene Alias

2210410K23Rik; 8030473O16; C20orf21; DACA-1; DACA-1 homolog; Dermatomyositis associated with cancer putative autoantigen 1; dermatomyositis associated with cancer putative autoantigen 1 homolog; fb49c02; wu:fb49c02; wu:fi19h06; wu:fj87f09; wu:fp06c11; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1; YTH domain-containing family protein 1; YTH N(6)-methyladenosine RNA binding protein 1; YTH N6-methyladenosine RNA binding protein 1; Ythdf1; zgc:55657

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

296467

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

0

Gene Symbols

YTHDF1

Immunogen

synthetic peptide directed towards the N-terminal region of rat YTHDF1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This target displays homology in the following species: Cow: 86%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451)
  • M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625)
  • Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440)
  • Required to facilitate learning and memory formation in the hippocampus by enhancing protein synthesis upon neuronal stimulation: in response to neuronal stimulation, binds to m6A-containing neuronal mRNAs, promoting their translation, thereby contributing to learning and memory
  • Acts as a regulator of axon guidance by binding to m6A-containing ROBO3 transcripts, thereby promoting their translation
  • Acts as a negative regulator of antigen cross-presentation in myeloid dendritic cells
  • Acts by binding and promoting translation of m6A-containing transcripts encoding proteins involved in lysosomal degradation and phagosome maturation, leading to increased antigen degradation in myeloid dendritic cells
  • In the context of tumorigenesis, negative regulation of antigen cross-presentation limits the anti-tumor response by reducing efficiency of tumor-antigen cross-presentation
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA570276

--


Antigen:
YTHDF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YTHDF1

Gene Alias:
2210410K23Rik; 8030473O16; C20orf21; DACA-1; DACA-1 homolog; Dermatomyositis associated with cancer putative autoantigen 1; dermatomyositis associated with cancer putative autoantigen 1 homolog; fb49c02; wu:fb49c02; wu:fi19h06; wu:fj87f09; wu:fp06c11; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1; YTH domain-containing family protein 1; YTH N(6)-methyladenosine RNA binding protein 1; YTH N6-methyladenosine RNA binding protein 1; Ythdf1; zgc:55657

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
296467

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
YTHDF1

Immunogen:
synthetic peptide directed towards the N-terminal region of rat YTHDF1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA570277

--


Antigen:
PPP2R3C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppp2r3c

Gene Alias:
4930511A21Rik; 5730412A08Rik; C14orf10; chromosome 14 open reading frame 10; G4-1; G5pr; hypothetical protein LOC533147; MNCb-1932; phosphatase subunit gene g4-1; Ppp2r3c; protein phosphatase 2 (formerly 2A), regulatory subunit B''; protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma; protein phosphatase 2 regulatory subunit B'', gamma; protein phosphatase 2 regulatory subunit B''gamma; protein phosphatase 2, regulatory subunit B'', gamma; protein phosphatase subunit G5PR; RGD1309207; rhabdomyosarcoma antigen MU-RMS-40.6A; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C; rhabdomyosarcoma antigen Mu-RMS-40.6C; serine/threonine-protein phosphatase 2A regulatory subunit B'' gamma subunit; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; similar to phosphatase subunit gene g4-1; zgc:55473

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
362739

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q6AXZ3

Gene Symbols:
Ppp2r3c

Immunogen:
synthetic peptide directed towards the middle region of human PPP2R3C

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA570278

--


Antigen:
FBXO34

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fbxo34

Gene Alias:
2900057B08Rik; 5830426G16Rik; CGI-301; F-box only protein 34; F-box protein 34; Fbx34; FBXO34; LOW QUALITY PROTEIN: F-box only protein 34; protein CGI-301

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
305830

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
Fbxo34

Immunogen:
synthetic peptide corresponding to a region of mouse FBXO34

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA570280

--


Antigen:
GPATCH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GPATCH2

Gene Alias:
5830433G22Rik; 5830436K05Rik; AI427714; AI447508; AW107440; AW491060; cancer/testis antigen 110; CT110; G patch domain containing 2; G patch domain-containing protein 2; GPATC2; G-patch domain containing 2; GPATCH2; PPP1R30; protein phosphatase 1, regulatory subunit 30; RP11-361K17.1; si:ch211-57i17.3; si:ch73-21k16.4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
289362

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
GPATCH2

Immunogen:
synthetic peptide directed towards the C-terminal region of rat GPATCH2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG