PIPA570556

MTMR6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA570556-Each-of-1 In Stock ₹ 44,705.10

PIPA570556 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MTMR6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MTMR6

Gene Alias

4022440C11Rik; AI428804; AU041072; MTMR6; myotubularin related protein 6; Myotubularin-like protein 6-like protein; myotubularin-related protein 6; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9107

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q9Y217

Gene Symbols

MTMR6

Immunogen

synthetic peptide directed towards the middle region of human MTMR6

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This target displays homology in the following species: Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Rabbit: 86%; Rat: 79% Phosphatase that acts on lipids with a phosphoinositol headgroup (PubMed:19038970, PubMed:22647598)
  • Dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,5-bisphosphate (PubMed:19038970, PubMed:22647598) (Probable)
  • Binds with high affinity to phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) but also to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 5-phosphate (PtdIns(5)P), phosphatidic acid and phosphatidylserine (PubMed:19038970)
  • Negatively regulates ER-Golgi protein transport
  • Probably in association with MTMR9, plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3-phosphate in membrane ruffles (PubMed:24591580)
  • Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4(+) T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3-phosphate (PubMed:15831468)
  • Negatively regulates proliferation of reactivated CD4(+) T-cells (PubMed:16847315)
  • In complex with MTMR9, negatively regulates DNA damage-induced apoptosis (PubMed:19038970, PubMed:22647598)
  • The formation of the MTMR6-MTMR9 complex stabilizes both MTMR6 and MTMR9 protein levels (PubMed:19038970)
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA570556

--


Antigen:
MTMR6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTMR6

Gene Alias:
4022440C11Rik; AI428804; AU041072; MTMR6; myotubularin related protein 6; Myotubularin-like protein 6-like protein; myotubularin-related protein 6; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9107

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9Y217

Gene Symbols:
MTMR6

Immunogen:
synthetic peptide directed towards the middle region of human MTMR6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA570557

--


Antigen:
P4HA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
P4HA2

Gene Alias:
4-PH alpha 2; 4-PH alpha-2; 4PHalpha2; AA407196; C76437; collagen prolyl 4-hydroxylase alpha(II); C-P4Halpha(II); hypothetical protein LOC507327; P4HA2; P4hl; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2; prolyl 4-hydroxylase A; Prolyl 4-hydroxylase alpha IIa subunit; prolyl 4-hydroxylase subunit alpha 2; prolyl 4-hydroxylase subunit alpha-2; prolyl 4-hydroxylase, alpha polypeptide II; UNQ290/PRO330; zgc:91948

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8974

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
O15460

Gene Symbols:
P4HA2

Immunogen:
synthetic peptide directed towards the middle region of human P4HA2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA570559

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Antigen:
PRSS58

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRSS58

Gene Alias:
1700020H15; LOC506919 protein; LOW QUALITY PROTEIN: serine protease 58; probable inactive serine protease 58; probable inactive trypsin-X3; protease, serine 58; protease, serine, 58; PRSS1; PRSS58; Putative inactive serine protease 58; putative trypsin-X3; serine protease 58; TRY1; trypsin X3; trypsin-X3; Tryx3; UNQ2540; UNQ2540/PRO6090

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
136541

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8IYP2

Gene Symbols:
PRSS58

Immunogen:
synthetic peptide directed towards the middle region of human PRSS58

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA570560

--


Antigen:
PRSS58

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRSS58

Gene Alias:
1700020H15; LOC506919 protein; LOW QUALITY PROTEIN: serine protease 58; probable inactive serine protease 58; probable inactive trypsin-X3; protease, serine 58; protease, serine, 58; PRSS1; PRSS58; Putative inactive serine protease 58; putative trypsin-X3; serine protease 58; TRY1; trypsin X3; trypsin-X3; Tryx3; UNQ2540; UNQ2540/PRO6090

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
136541

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8IYP2

Gene Symbols:
PRSS58

Immunogen:
synthetic peptide directed towards the middle region of human PRSS58

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG