PIPA570717

MREG Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA570717-Each-of-1 In Stock ₹ 44,705.10

PIPA570717 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MREG

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MREG

Gene Alias

dilute suppressor protein; Dilute suppressor protein homolog; Dsu; Gm974; HDCGA21P; Melanoregulin; MREG; RGD1562333; WDT2; Whn-dependent transcript 2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55686

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q8N565

Gene Symbols

MREG

Immunogen

synthetic peptide directed towards the C-terminal region of human MREG

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100% Probably functions as cargo-recognition protein that couples cytoplasmic vesicles to the transport machinery
  • Plays a role in hair pigmentation, a process that involves shedding of melanosome-containing vesicles from melanocytes, followed by phagocytosis of the melanosome-containing vesicles by keratinocytes
  • Functions on melanosomes as receptor for RILP and the complex formed by RILP and DCTN1, and thereby contributes to retrograde melanosome transport from the cell periphery to the center
  • Overexpression causes accumulation of late endosomes and/or lysosomes at the microtubule organising center (MTOC) at the center of the cell
  • Probably binds cholesterol and requires the presence of cholesterol in membranes to function in microtubule-mediated retrograde organelle transport
  • Binds phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate and phosphatidylinositol 3,5-bisphosphate, but not phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 4,5-bisphosphate
  • Required for normal phagosome clearing and normal activation of lysosomal enzymes in lysosomes from retinal pigment epithelium cells (PubMed:19240024)
  • Required for normal degradation of the lipofuscin component N-retinylidene-N-retinylethanolamine (A2E) in the eye
  • May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA570717

--


Antigen:
MREG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MREG

Gene Alias:
dilute suppressor protein; Dilute suppressor protein homolog; Dsu; Gm974; HDCGA21P; Melanoregulin; MREG; RGD1562333; WDT2; Whn-dependent transcript 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55686

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8N565

Gene Symbols:
MREG

Immunogen:
synthetic peptide directed towards the C-terminal region of human MREG

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA570718

--


Antigen:
NUDT7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUDT7

Gene Alias:
1300007B24Rik; 2210404C19Rik; coenzyme A diphosphatase; nucleoside diphosphate-linked moiety X motif 7; nudix (nucleoside diphosphate linked moiety X)-type motif 7; nudix hydrolase 7; nudix motif 7; Nudt7; Peroxisomal coenzyme A diphosphatase NUDT7; peroxisomal coenzyme A diphosphatase NUDT7-like

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
283927

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P0C024

Gene Symbols:
NUDT7

Immunogen:
synthetic peptide directed towards the N-terminal region of human NUDT7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA570719

--


Antigen:
RPL36A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPL36A

Gene Alias:
60S ribosomal protein L36a; 60S ribosomal protein L36-A; 60S ribosomal protein L44; Cell growth-inhibiting gene 15 protein; cell migration-inducing gene 6 protein; dJ164F3.3 (ribosomal protein L44); GIG15; L36A; L39; L44L; L44-like ribosomal protein; Large ribosomal subunit protein eL36-A; Large ribosomal subunit protein eL42; MIG6; ribosomal 60S subunit protein L36A; ribosomal protein L36A; ribosomal protein L44; RPL36A; RPL39A; RPL39B; Rpl44; YL39; YM9646.06; YMR194W

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6173

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P83881

Gene Symbols:
RPL36A

Immunogen:
synthetic peptide directed towards the middle region of human RPL36A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA570722

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Antigen:
Rab6b

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rab6b

Gene Alias:
9630015C03; AI844641; C330006L04Rik; D9Bwg0185e; Rab6b; RAB6B, member RAS oncogene family; ras-related protein Rab-6B; small GTPase RAB6B; small GTP-binding protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
270192

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P61294

Gene Symbols:
Rab6b

Immunogen:
synthetic peptide directed towards the C-terminal region of mouse Rab6b

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG