PIPA570888
DENND3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA570888-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA570888 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
DENND3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DENND3
Gene Alias
AI447457; DENN domain containing 3; DENN domain-containing protein 3; DENN/MADD domain containing 3; Dennd3; E030003N15Rik; KIAA0870
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22898
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.
A2RUS2
Gene Symbols
DENND3
Immunogen
synthetic peptide directed towards the C-terminal region of human DENND3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Guanine nucleotide exchange factor (GEF) activating RAB12
- Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form (PubMed:20937701)
- Regulates autophagy in response to starvation through RAB12 activation
- Starvation leads to ULK1/2-dependent phosphorylation of Ser-472 and Ser-490, which in turn allows recruitment of 14-3-3 adapter proteins and leads to up-regulation of GEF activity towards RAB12
- Also plays a role in protein transport from recycling endosomes to lysosomes, regulating, for instance, the degradation of the transferrin receptor and of the amino acid transporter PAT4 (PubMed:20937701)
- Starvation also induces phosphorylation at Tyr-858, which leads to up-regulated GEF activity and initiates autophagy
- [UniProt]
Compare Similar Items
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Antigen: DENND3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DENND3
Gene Alias: AI447457; DENN domain containing 3; DENN domain-containing protein 3; DENN/MADD domain containing 3; Dennd3; E030003N15Rik; KIAA0870
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22898
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: A2RUS2
Gene Symbols: DENND3
Immunogen: synthetic peptide directed towards the C-terminal region of human DENND3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DENND3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DENND3
Gene Alias:
AI447457; DENN domain containing 3; DENN domain-containing protein 3; DENN/MADD domain containing 3; Dennd3; E030003N15Rik; KIAA0870
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22898
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
A2RUS2
Gene Symbols:
DENND3
Immunogen:
synthetic peptide directed towards the C-terminal region of human DENND3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: EPS15R
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EPS15L1
Gene Alias: 9830147J04Rik; AI593686; epidermal growth factor receptor pathway substrate 15 like 1; epidermal growth factor receptor pathway substrate 15-like 1; epidermal growth factor receptor pathway substrate 15-related sequence; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15l1; EPS15R; eps15-related protein; Eps15-rs
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13859
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q60902
Gene Symbols: EPS15L1
Immunogen: synthetic peptide directed towards the C-terminal region of mouse EPS15R
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
EPS15R
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EPS15L1
Gene Alias:
9830147J04Rik; AI593686; epidermal growth factor receptor pathway substrate 15 like 1; epidermal growth factor receptor pathway substrate 15-like 1; epidermal growth factor receptor pathway substrate 15-related sequence; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15l1; EPS15R; eps15-related protein; Eps15-rs
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13859
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q60902
Gene Symbols:
EPS15L1
Immunogen:
synthetic peptide directed towards the C-terminal region of mouse EPS15R
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: FAM101B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RFLNB
Gene Alias: 1500005K14Rik; cfm; Cfm1; Fam101b; family with sequence similarity 101 member B; family with sequence similarity 101, member B; filamin-interacting protein FAM101B; filamin-interacting protein FAM101B; refilin-B; MGC45871; protein FAM101B; refilin B; RefilinB; refilin-B; regulator of filamin protein B; RFLNB; RGD1359691
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 359845
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q8N5W9
Gene Symbols: RFLNB
Immunogen: synthetic peptide directed towards the N-terminal region of human FAM101B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FAM101B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RFLNB
Gene Alias:
1500005K14Rik; cfm; Cfm1; Fam101b; family with sequence similarity 101 member B; family with sequence similarity 101, member B; filamin-interacting protein FAM101B; filamin-interacting protein FAM101B; refilin-B; MGC45871; protein FAM101B; refilin B; RefilinB; refilin-B; regulator of filamin protein B; RFLNB; RGD1359691
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
359845
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q8N5W9
Gene Symbols:
RFLNB
Immunogen:
synthetic peptide directed towards the N-terminal region of human FAM101B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FAM102A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FAM102A
Gene Alias: bA203J24.7; C230093N12Rik; C9orf132; Early estrogen-induced gene 1 protein; EEIG1; FAM102A; family with sequence similarity 102 member A; family with sequence similarity 102, member A; protein FAM102A; sym-3 homolog A; SYM-3A
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 399665
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q5T9C2
Gene Symbols: FAM102A
Immunogen: synthetic peptide directed towards the Middle region of human FAM102A
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FAM102A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FAM102A
Gene Alias:
bA203J24.7; C230093N12Rik; C9orf132; Early estrogen-induced gene 1 protein; EEIG1; FAM102A; family with sequence similarity 102 member A; family with sequence similarity 102, member A; protein FAM102A; sym-3 homolog A; SYM-3A
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
399665
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q5T9C2
Gene Symbols:
FAM102A
Immunogen:
synthetic peptide directed towards the Middle region of human FAM102A
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG