PIPA571089

FAM21A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA571089-Each-of-1 In Stock ₹ 44,191.74

PIPA571089 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

FAM21A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WASHC2A

Gene Alias

alternative protein FAM21B; bA56A21.1; bA98I6.1; FAM21A; FAM21B; family with sequence similarity 21 member A; family with sequence similarity 21, member A; family with sequence similarity 21, member B; WASH complex subunit 2A; WASH complex subunit FAM21A; WASH complex subunit FAM21B; WASHC2A

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

387680

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q641Q2

Gene Symbols

WASHC2A

Immunogen

synthetic peptide directed towards the C-terminal region of human FAM21A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This target displays homology in the following species: Cow: 77%; Dog: 93%; Horse: 86%; Human: 100%; Pig: 85%; Rabbit: 79%; Rat: 77% Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes inhibits WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization and is involved in the fission of tubules that serve as transport intermediates during endosome sorting
  • Mediates the recruitment of the WASH core complex to endosome membranes via binding to phospholipids and VPS35 of the retromer CSC
  • Mediates the recruitment of the F-actin-capping protein dimer to the WASH core complex probably promoting localized F-actin polymerization needed for vesicle scission
  • Via its C-terminus binds various phospholipids, most strongly phosphatidylinositol 4-phosphate (PtdIns-(4)P), phosphatidylinositol 5-phosphate (PtdIns-(5)P) and phosphatidylinositol 3,5-bisphosphate (PtdIns-(3,5)P2)
  • Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1
  • Required for the association of DNAJC13, ENTR1, ANKRD50 with retromer CSC subunit VPS35
  • Required for the endosomal recruitment of CCC complex subunits COMMD1 and CCDC93 as well as the retriever complex subunit VPS35L
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA571089

--


Antigen:
FAM21A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WASHC2A

Gene Alias:
alternative protein FAM21B; bA56A21.1; bA98I6.1; FAM21A; FAM21B; family with sequence similarity 21 member A; family with sequence similarity 21, member A; family with sequence similarity 21, member B; WASH complex subunit 2A; WASH complex subunit FAM21A; WASH complex subunit FAM21B; WASHC2A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
387680

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q641Q2

Gene Symbols:
WASHC2A

Immunogen:
synthetic peptide directed towards the C-terminal region of human FAM21A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA571090

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Antigen:
NUTM2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUTM2A

Gene Alias:
FAM22A; family with sequence similarity 22, member A; KIAA2020; NUT family member 2A; NUTM2A; protein FAM22A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
728118

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8IVF1

Gene Symbols:
NUTM2A

Immunogen:
synthetic peptide directed towards the C-terminal region of human NUTM2A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA571091

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Antigen:
NUTM2F

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUTM2F

Gene Alias:
FAM22F; family with sequence similarity 22, member F; NUT family member 2F; NUTM2F; NUTMF; protein FAM22F

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54754

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
A1L443

Gene Symbols:
NUTM2F

Immunogen:
synthetic peptide directed towards the C-terminal region of human NUTM2F

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA571092

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Antigen:
FAM24B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FAM24B

Gene Alias:
FAM24B; family with sequence similarity 24 member B; family with sequence similarity 24, member B; protein FAM24B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
196792

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8N5W8

Gene Symbols:
FAM24B

Immunogen:
synthetic peptide directed towards the N-terminal region of human FAM24B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG