PIPA571356

Nova-2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA571356-Each-of-1 In Stock ₹ 44,705.10

PIPA571356 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Nova-2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOVA2

Gene Alias

ANOVA; astrocytic NOVA1-like RNA-binding protein; Gm1424; neuro-oncological ventral antigen 2; neuro-oncological ventral antigen 3; NOVA alternative splicing regulator 2; NOVA2; NOVA3; RNA-binding protein Nova-2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4858

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q9UNW9

Gene Symbols

NOVA2

Immunogen

synthetic peptide directed towards the middle region of human Nova-2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Paraneoplastic opsoclonus myoclonus ataxia (POMA) is a neurologic disorder thought to be mediated by an autoimmune attack against onconeural disease antigens that are expressed by gynecologic or lung tumors and by neurons
  • Nova-1 and -2 are both POMA disease antigens
  • The autoimmune attack against Nova-2 in POMA patients results in latent cancer, reduced inhibitory control of movements, and dementia
  • Nova-2 is closely related to Nova-1, and is expressed at high levels in neurons during development and at lower levels in the adult lung
  • In the postnatal mouse brain, Nova-2 is expressed in a pattern that is largely reciprocal with Nova-1, including high levels of Nova-2 expression in the neocortex and hippocampus
  • Both Novas are RNA binding proteins, and Nova-2 binds RNA with high affinity and with sequence specificity that differs from Nova-1
  • They regulate neuronal pre-messenger RNA splicing by directly binding to RNA
  • Nova-2 target genes function either in the synapse or in axon guidance indicating that Nova-2 is a major regulator of synaptic function.

Compare Similar Items

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Thermo Scientific

PIPA571356

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Antigen:
Nova-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOVA2

Gene Alias:
ANOVA; astrocytic NOVA1-like RNA-binding protein; Gm1424; neuro-oncological ventral antigen 2; neuro-oncological ventral antigen 3; NOVA alternative splicing regulator 2; NOVA2; NOVA3; RNA-binding protein Nova-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4858

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9UNW9

Gene Symbols:
NOVA2

Immunogen:
synthetic peptide directed towards the middle region of human Nova-2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA571360

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Antigen:
RHCE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RHCE

Gene Alias:
(C)ces type 1 Rhesus blood group D antigen; blood group Rh(CE) polypeptide; blood group RhCcEe antigen; blood group RhCE polypeptide; CD240CE; RH; Rh blood group antigen Evans; Rh blood group C antigen; Rh blood group CcEe antigens; Rh blood group protein; Rh blood group, CcEe antigens; rh polypeptide 1; Rh polypeptide I; Rh30A; Rh4; RHC; RHCE; RhCE blood group antigens; RHCE blood group variant Crawford antigen Rh43; RHE; rhesus blood group antigen, RhC antigen; Rhesus blood group CE protein; Rhesus blood group E antigen; rhesus blood group little e antigen; Rhesus blood group Rhce antigen; rhesus C/E antigens; Rhesus system C and E polypeptides; RhIVb(J); RHIXB; RhPI; RhVI; RhVIII; silenced Rh blood group CcEe antigen; truncated RhCcEe antigen; truncated RHCE

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6006

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P18577

Gene Symbols:
RHCE

Immunogen:
synthetic peptide directed towards the middle region of human RHCE

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA571363

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Antigen:
SLC35A2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC35A2

Gene Alias:
AI327289; CDG2M; CDGX; Had1; Had-1; mUGT1; Sfc8; SLC35A2; solute carrier family (UDP-N-acetylglucosamine transporter), member 2; solute carrier family 35 (UDP-galactose transporter) member 2; solute carrier family 35 (UDP-galactose transporter), member 2; solute carrier family 35 (UDP-galactose transporter), member A2; solute carrier family 35 member A2; solute carrier family 35, member A2; UDP-galactose translocator; UDP-galactose transporter; UDP-Gal-Tr; UGALT; UGAT; UGT; UGT1; UGT2; UGTL

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22232

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9R0M8

Gene Symbols:
SLC35A2

Immunogen:
synthetic peptide directed towards the C terminal region of mouse SLC35A2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA571367

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Antigen:
NRXN3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NRXN3

Gene Alias:
C14orf60; KIAA0743; neurexin 3; Neurexin 3alpha; neurexin III; Neurexin III-alpha; Neurexin III-beta; Neurexin-3; neurexin-3-alpha; Neurexin-3-beta; Neurexin-3-beta, C-terminal fragment; Neurexin-3-beta, soluble form; Nrxn3; NRXN3-CTF

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9369

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9HDB5, Q9Y4C0

Gene Symbols:
NRXN3

Immunogen:
synthetic peptide directed towards the C terminal region of human NRXN3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG