PIPA571645

SDHD Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA571645-Each-of-1 In Stock ₹ 44,619.54

PIPA571645 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

SDHD

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SDHD

Gene Alias

3110001M13Rik; AVLL5809; C78570; CBT1; CII-4; CWS3; CybS; PGL; PGL1; PRO19626; QPs3; SDH4; SDHD; Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; succinate dehydrogenase complex subunit D; succinate dehydrogenase complex subunit D integral membrane protein; succinate dehydrogenase complex, subunit D, integral membrane protein; succinate-ubiquinone oxidoreductase cytochrome b small subunit; Succinate-ubiquinone reductase membrane anchor subunit

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6392

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

O14521

Gene Symbols

SDHD

Immunogen

KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SDHD

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The mitochondrial succinate dehydrogenase complex subunit D (SDHD) is one of four proteins that make up the tricarboxylic cycle enzyme succinate dehydrogenase (SCH)
  • Studies have shown that mutations in SDHD often leads to hereditary paragangliomas, usually benign tumors of the autonomic nervous system, suggesting that SDHD also plays a role as a tumor-suppressor gene
  • In one family with a nonsense mutation (R22X) in the SDHD gene, a loss of heterozygosity was found in the paragangliomas, and within these tumors the enzymatic activity of Complex II in the mitochondrial respiratory chain was completely abolished
  • Furthermore, high levels of angiogenic factors EPAS1 and VEGF was observed, which may stimulate tumor growth.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA571645

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Antigen:
SDHD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SDHD

Gene Alias:
3110001M13Rik; AVLL5809; C78570; CBT1; CII-4; CWS3; CybS; PGL; PGL1; PRO19626; QPs3; SDH4; SDHD; Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; succinate dehydrogenase complex subunit D; succinate dehydrogenase complex subunit D integral membrane protein; succinate dehydrogenase complex, subunit D, integral membrane protein; succinate-ubiquinone oxidoreductase cytochrome b small subunit; Succinate-ubiquinone reductase membrane anchor subunit

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6392

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O14521

Gene Symbols:
SDHD

Immunogen:
KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SDHD

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA571658

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Antigen:
UNQ6493/PRO21345

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UNQ6493/PRO21345

Gene Alias:
UNQ6493/PRO21345

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
0

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q6UXR8

Gene Symbols:
UNQ6493/PRO21345

Immunogen:
KLH conjugated synthetic peptide between 78-107 amino acids from the C-terminal region of human UNQ6493

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA571659

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Antigen:
ASM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smpd1

Gene Alias:
Acid sphingomyelinase; ASM; aSMase; A-SMase; NPD; Smpd1; Sphingomyelin phosphodiesterase; sphingomyelin phosphodiesterase 1; sphingomyelin phosphodiesterase 1, acid lysosomal; Zn-SMase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6609

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P17405

Gene Symbols:
Smpd1

Immunogen:
KLH conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human SMPD1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA571660

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Antigen:
MAFB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAFB

Gene Alias:
b-maf; c-Maf; kr; Kreisler; Kreisler (maf-related) leucine zipper protein; Kreisler maf-related leucine zipper homolog; Kreisler maf-related leucine zipper homolog (b-maf); KRML; Krml1; LOW QUALITY PROTEIN: transcription factor MafB; maf; MAF bZIP transcription factor B; Maf1; MAFB; maf-B; MAFB/Kreisler basic region/leucine zipper transcription factor; MCTO; MGC43127; segmentation protein Kr; si:ch73-337g9.1; transcription factor Maf; Transcription factor Maf-1; transcription factor MafB; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b); v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian); V-maf musculoaponeurotic fibrosarcoma oncogene homolog B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9935

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9Y5Q3

Gene Symbols:
MAFB

Immunogen:
KLH conjugated synthetic peptide between 266-292 amino acids from the C-terminal region of human MAFB

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG